scholarly journals Development and validation of a low-cost, portable and wireless gait assessment tool

2014 ◽  
Vol 36 (4) ◽  
pp. 541-546 ◽  
Author(s):  
Catherine A. Macleod ◽  
Bernard A. Conway ◽  
David B. Allan ◽  
Sujay S. Galen
2020 ◽  
Vol 16 (4) ◽  
pp. 456-464
Author(s):  
Danilo F. Rodrigues ◽  
Hérida R.N. Salgado

Background: A simple, eco-friendly and low-cost Infrared (IR) method was developed and validated for the analysis of Cefepime Hydrochloride (CEF) in injectable formulation. Different from some other methods, which employ organic solvents in the analyses, this technique does not use these types of solvents, removing large impacts on the environment and risks to operators. Objective: This study aimed at developing and validating a green analytical method using IR spectroscopy for the determination of CEF in pharmaceutical preparations. Methods: The method was validated according to ICH guidelines and the quantification of CEF was performed in the spectral region absorbed at 1815-1745 cm-1 (stretching of the carbonyl group of β- lactam ring). Results: The validated method showed to be linear (r = 0.9999) in the range of 0.2 to 0.6 mg/pellet of potassium bromide, as well as for the parameters of selectivity, precision, accuracy, robustness and Limits of Detection (LOD) and Quantification (LOQ), being able to quantify the CEF in pharmaceutical preparations. The CEF content obtained by the IR method was 103.86%. Conclusion: Thus, the method developed may be an alternative in the quality control of CEF sample in lyophilized powder for injectable solution, as it presented important characteristics in the determination of the pharmaceutical products, with low analysis time and a decrease in the generation of toxic wastes to the environment.


Toxicon X ◽  
2020 ◽  
Vol 8 ◽  
pp. 100064
Author(s):  
Auwal A. Bala ◽  
Abubakar I. Jatau ◽  
Ismaeel Yunusa ◽  
Mustapha Mohammed ◽  
Al-Kassim H. Mohammed ◽  
...  

2020 ◽  
Vol 196 ◽  
pp. 105705 ◽  
Author(s):  
S. Summa ◽  
G. Tartarisco ◽  
M. Favetta ◽  
A. Buzachis ◽  
A. Romano ◽  
...  
Keyword(s):  
Low Cost ◽  

2016 ◽  
Vol 31 (4) ◽  
pp. 310-317 ◽  
Author(s):  
Wai Kin Yip ◽  
Siti Zubaidah Mordiffi ◽  
Hung Chew Wong ◽  
Emily Neo Kim Ang

Author(s):  
Hyeona So ◽  
Dahyun Park ◽  
Mi-Kyung Choi ◽  
Young-Sun Kim ◽  
Min-Jeong Shin ◽  
...  

Food literacy refers to the knowledge, skills, and attitudes required for individuals to choose foods that promote health. As the rate of diet-related diseases increases, food literacy is becoming more important. However, there are no tools available to evaluate food literacy among the Korean elderly. We derived 547 questions from a literature review and, after three rounds of Delphi surveys, selected 33 preliminary questions. We calculated the content validity ratio of the questions and applied a face validity procedure. We then selected 32 questions, assessed their validity, and distributed them as a questionnaire to 205 elderly people. We then conducted exploratory factor analysis (EFA) to determine the validity of the questionnaire and used an internal consistency index (Cronbach’s α coefficient) to determine reliability. Based on the factor analysis, 13 questions were selected, distributed among three factors, and evaluated using the Kaiser–Meyer–Olkin (KMO) and Bartlett sphericity tests. The factor analysis showed that KMO was 0.872, which is a highly acceptable score, and the Bartlett sphericity test was χ2 = 1,374.69 at p = 0.00. The food literacy questionnaire developed in this study will likely be helpful for improving the healthcare of elderly people.


2014 ◽  
Vol 98 ◽  
pp. 198
Author(s):  
LaPointe D. Rudow ◽  
B. Iacoviello ◽  
J. Braoude ◽  
T. Jennings ◽  
S. Vaidya ◽  
...  

2019 ◽  
Vol 65 (2) ◽  
pp. 49-54
Author(s):  
Amalia Miklos ◽  
Amelia Tero-Vescan ◽  
Lénárd Farczádi ◽  
Daniela-Lucia Muntean

AbstractObjective: The purpose of this study was to develop a low-cost, yet sensitive and precise UHPLC method for the quantitative determination of ostarine from dietary supplements (DS) for athletes. The analytical performance of the method was verified on a DS legally acquired from a specialized website for athletes. The uniformity of mass and content of the ostarine DS was also verified.Methods: For the quantitative determination of ostarine a UHPLC method was developed and validated. The separation was performed using a reversed-phase C18 column, using a mixture of 75% methanol: 25% formic acid 0.1% in isocratic elution, at a flow rate of 0.5 ml/min. The uniformity of mass and content of DS was performed following the methodology described in the European Pharmacopoeia 7th Edition.Results: The validated method was specific and linear on the concentration range of 1-25 µg/ml and was precise and accurate at all concentration levels, according to the official guidelines for validating analytical methods. An average mass of 510 mg content was obtained for the ostarine capsules, with an RSD of 2.41%. Regarding the uniformity of the content, an average of 4.65 mg ostarine/capsule was obtained with an RSD of 1.05%.Conclusions: The developed UHPLC method was suitable, rapid, sensitive and allowed quantitative determination of active substance content in a DS with ostarine (92.91% ostarine/capsule from 5 mg ostarine/capsule declared by the manufacturer).


2020 ◽  
Author(s):  
Young Ho Yun ◽  
Sinae Oh ◽  
Jin Ah Sim ◽  
Sujee Lee ◽  
Eun-Jung Sohn

Abstract Objectives We developed the Health-Friendly Activity Index (HFAI) to measure the health-friendly activity of corporations or organizations comprehensively. We validated the developed tool and reported on its use as an assessment tool to improve consumers’ health-related outcomes.Study Design This is a cross-sectional studyPUBH-D-20-02610 Development of the HFAI questionnaire followed a three-phase process: item generation, item construction, and validation with field testing. Using relevance and feasibility criteria, we developed a 105-item questionnaire with six domains (Governance and Infrastructure, Needs Assessment, Planning, Implementation, Monitoring and Feedback, and Outcomes). To assess the sensitivity and validity of the questionnaire, we recruited two different groups. We assessed Group One (31 companies) based on their recent sustainability reports and compared their HFAI scores with the Contribution Assessment Tool for Consumer’s Health (CATCH) scores from 400 people from the general Korean population. For Group Two, we recruited 19 worksites and asked them to complete the HFAI and CATCH.Results Each domain of HFAI exhibited a Cronbach’s α coefficient between 0.382 and 1.000 for Group One and a Cronbach’s α coefficient between 0.676 and 0.938 for Group Two.


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