Measurement of brown adipose tissue mass using a novel dual-echo magnetic resonance imaging approach: A validation study

Metabolism ◽  
2013 ◽  
Vol 62 (8) ◽  
pp. 1189-1198 ◽  
Author(s):  
Milja Holstila ◽  
Kirsi A. Virtanen ◽  
Tove J. Grönroos ◽  
Jukka Laine ◽  
Virva Lepomäki ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Adipose Tissue ◽  
Magnetic Resonance ◽  
Validation Study ◽  
Resonance Imaging ◽  
Tissue Mass ◽  
Brown Adipose ◽  
Adipose Tissue Mass ◽  
Imaging Approach ◽  
Dual Echo

High-resolution magnetic resonance imaging tracks changes in organ and tissue mass in obese and aging rats

2002 ◽  
Vol 282 (3) ◽  
pp. R890-R899 ◽  
Author(s):  
Haiying Tang ◽  
Joseph R. Vasselli ◽  
Ed X. Wu ◽  
Carol N. Boozer ◽  
Dympna Gallagher
Keyword(s):  
Magnetic Resonance Imaging ◽  
Adipose Tissue ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Soft Tissues ◽  
Whole Body ◽  
Resonance Imaging ◽  
Sprague Dawley ◽  
Tissue Mass

Magnetic resonance imaging (MRI) has the ability to discriminate between various soft tissues in vivo. Whole body, specific organ, total adipose tissue (TAT), intra-abdominal adipose tissue (IAAT), and skeletal muscle (SM) weights determined by MRI were compared with weights determined by dissection and chemical analysis in two studies with male Sprague-Dawley rats. A 4.2-T MRI machine acquired high-resolution, in vivo, longitudinal whole body images of rats as they developed obesity or aged. Weights of the whole body and specific tissues were determined using computer image analysis software, including semiautomatic segmentation algorithms for volume calculations. High correlations were found for body weight ( r = 0.98), TAT ( r = 0.99), and IAAT ( r = 0.98) between MRI and dissection and chemical analyses. MRI estimated the weight of the brain, kidneys, and spleen with high accuracy ( r > 0.9), but overestimated IAAT, SM, and liver volumes. No differences were detected in organ weights using MRI and dissection measurements. Longitudinal MRI measurements made during the development of obesity and aging accurately represented changes in organ and tissue mass.

scholarly journals Anatomical and Functional Assessment of Brown Adipose Tissue by Magnetic Resonance Imaging

Obesity ◽  
2012 ◽  
Vol 20 (7) ◽  
pp. 1519-1526 ◽  
Author(s):  
Y. Iris Chen ◽  
Aaron M. Cypess ◽  
Christina A. Sass ◽  
Anna-Liisa Brownell ◽  
Kimmo T. Jokivarsi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Adipose Tissue ◽  
Magnetic Resonance ◽  
Brown Adipose Tissue ◽  
Functional Assessment ◽  
Resonance Imaging ◽  
Brown Adipose

scholarly journals Exploring the Effects of Exercise on Brown Adipose Tissue Volumes and T2 Values Using Magnetic Resonance Imaging at 7 Tesla

2021 ◽  
Author(s):  
Yan Zeng ◽  
Lei Gao ◽  
Shuying Shao ◽  
Xiaoshuai Chen ◽  
Ping Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Adipose Tissue ◽  
Magnetic Resonance ◽  
Brown Adipose Tissue ◽  
7 Tesla ◽  
Control Group ◽  
Resonance Imaging ◽  
Control Groups ◽  
Brown Adipose ◽  
And Control

Abstract Rationale and Objectives: We aimed to evaluate the effect of exercise on brown adipose tissue (BAT) volumes and T2 values in mice. Materials and Methods Twenty-five female Kunming mice were divided into two groups, a running group (n = 5) and a control group (n = 20). After 4 months, all magnetic resonance imaging (MRI) scans of mice were performed on a 7 Tesla (7T) MR scanner with T2-weighted imaging (T2WI) and a T2 mapping sequence. Interscapular brown adipose tissue (BAT) volumes and T2 values were measured. To reduce the impact of weight on the results, we compared the ratio of BAT volumes to body weights (V/W). The data are expressed as mean ± SD, the BAT V/W and T2 values were compared between the control and running groups using the Wilcoxon rank-sum test, P < 0.05 were considered statistically significant. Results Interscapular BAT volumes of the running group (n = 5) and control group (n = 20) were (180.09ml ± 59.80 ml) and (99.98ml ± 35.05ml), respectively. The V/W ratios of the running and control groups were (3.83ml/g ± 0.78ml/g) and (2.17ml/g ± 0.56ml/g), respectively. Interscapular BAT T2 values of the running and control groups were (76.07ms ± 10.82ms) and (61.22ms ± 15.98ms), respectively. Significant differences were found in the BAT V/W ratios (P = 0.0003, P < 0.001) and T2 values between the two groups (P = 0.0096, P < 0.05). BAT volume correlated positively with BAT T2 value (r = 0.75, p = 0.00002). Conclusions MRI is a non-invasive and quantitative method for identifying BAT, especially at ultra-high field like 7T. Long-term running increases BAT volume and T2 value, what's more, BAT volume correlates positively with BAT T2 value.

Characterization of brown adipose tissue by water-fat separated magnetic resonance imaging

2015 ◽  
Vol 42 (6) ◽  
pp. 1639-1645 ◽  
Author(s):  
Thobias Romu ◽  
Louise Elander ◽  
Olof Dahlqvist Leinhard ◽  
Martin E Lidell ◽  
Matthias J Betz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Adipose Tissue ◽  
Magnetic Resonance ◽  
Brown Adipose Tissue ◽  
Resonance Imaging ◽  
Brown Adipose
Sign in / Sign up

Export Citation Format

Share Document