scholarly journals Candida species from oral cavity of HIV-infected children exhibit reduced virulence factors in the HAART era

2017 ◽  
Vol 102 ◽  
pp. 74-81 ◽  
Author(s):  
Maristela Barbosa Portela ◽  
Elaine Lima de Amorim ◽  
Adrielle Mangabeira Santos ◽  
José Alexandre da Rocha Curvelo ◽  
Karol de Oliveira Martins ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Virulence Factors ◽  
Candida Species

scholarly journals Comparison of Virulence Factors of Different Candida Species Isolated from the Oral Cavity of Cancer Patients and Normal Individuals

2019 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mehrnoush Maheronnaghsh ◽  
Mahnaz Fatahinia ◽  
Parvin Dehghan ◽  
Ali Zarei Mahmoudabadi ◽  
Mahnaz Kheirkhah
Keyword(s):  
Oral Cavity ◽  
Cancer Patients ◽  
Virulence Factors ◽  
Candida Species ◽  
Normal Individuals

scholarly journals Candida species distribution, genotyping and virulence factors of Candida albicans isolated from the oral cavity of kidney transplant recipients of two geographic regions of Brazil

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Walicyranison Plinio da Silva-Rocha ◽  
Vitor Luiz de Brito Lemos ◽  
Terezinha Inês Estivalet Svidizisnki ◽  
Eveline Pipolo Milan ◽  
Guilherme Maranhão Chaves
Keyword(s):  
Candida Albicans ◽  
Oral Cavity ◽  
Kidney Transplant ◽  
Virulence Factors ◽  
Species Distribution ◽  
Candida Species ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Geographic Regions

scholarly journals Candida spp. occurrence in oral cavities of breastfeeding infants and in their mothers' mouths and breasts

2003 ◽  
Vol 17 (2) ◽  
pp. 151-155 ◽  
Author(s):  
Maria Stella Amorim da Costa Zöllner ◽  
Antonio Olavo Cardoso Jorge
Keyword(s):  
Oral Cavity ◽  
Candida Species ◽  
Statistical Difference ◽  
Control Group ◽  
Biochemical Tests ◽  
Candida Spp ◽  
Lactating Women ◽  
Sabouraud Agar ◽  
Breastfed Infants ◽  
Yeast Strains

This study aimed to determine the occurrence of Candida spp. in the oral cavity of predominantly breastfed infants and in their mothers' mouths and breasts, as well as in the oral cavity of bottlefed infants and in non-lactating women. One hundred and sixty nine women and eighty-five milk-fed infants took part in this study and were divided into four groups: 1) infants predominantly on breastfeeding (n = 55) and their mothers (n = 55); 2) infants on bottlefeeding (n = 30); 3) non-lactating women on whom oral collections were performed (n = 80) and, 4) non-lactating women on whom breast collections were performed (n = 34). Oral and mammary swabs were cultured on Sabouraud agar dextrose with chloramphenicol. The Candida yeast strains found were isolated and identified through morphological and biochemical tests. Candida species were much less frequent in infants who were predominantly breastfed than in those who were bottlefed. Yeasts were much more frequent on the breasts of lactating women, with statistical difference in relation to the control group.

scholarly journals Molecular characterization of Candida dubliniensis and Candida albicans in the oral cavity of drug abusers using duplex polymerase chain reaction

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Parastoo Hassani Abharian ◽  
Parvin Dehghan ◽  
Peyman Hassani Abharian ◽  
Sepideh Tolouei
Keyword(s):  
Polymerase Chain Reaction ◽  
Candida Albicans ◽  
Oral Cavity ◽  
Candida Species ◽  
Species Complex ◽  
Candida Dubliniensis ◽  
Drug Abusers ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Duplex Polymerase Chain Reaction

  Background and Purpose: Candida dubliniensis is closely related to the most pathogenic and prevalent yeast, namely C. albicans. Candida species can opportunistically overgrow in vulnerable individuals and cause a variety of diseases. The current study aimed to identify and isolate C. dubliniensis species present in the Candida albicans species complex identified in the oral cavity of drug abusers. Materials and Methods: This study was conducted on 53 strains of C. albicans species complex, isolated from the oral mucosa of drug abusers in Isfahan, Iran. DNA extraction was accomplished through boiling procedure. Duplex polymerase chain reaction (PCR) was performed to amplify ITS1-5.8S-ITS2 region using four specific primers. Fungal species were identified based on the difference in the size of the bands created in the Agarose gel. Results: Out of the 53 isolates under study, 30 (56.6%) and 14 (26.4%) samples were identified as C. albicans and C. dubliniensis, respectively. In the remaining 9 samples (17%), both types of Candida species were confirmed. Conclusion: The findings of the present study revealed the presence of a noticeable amount of C. dubliniensis in the oral cavity of drug abusers. Therefore, the probable presence of this fungus should be considered during the examination of oral infection among this group. To date, no research has directly investigated this issue in Iran.

scholarly journals Isolation of Candida species in children and their biofilm-forming ability on nano-composite surfaces

2020 ◽  
Vol 1 (1) ◽  
pp. 40-52
Author(s):  
Harina Akila Che Hussin ◽  
Nadiah Arshad ◽  
Siti Nor Humaira Nor Azemi ◽  
Raja Izzatun Nisa Raja Sahrul Hishan ◽  
Wan Nur Fatihah Wan Mohd Kamaluddin ◽  
...  
Keyword(s):  
Dental Caries ◽  
Oral Cavity ◽  
Buccal Mucosa ◽  
Candida Species ◽  
Soft Tissues ◽  
Tooth Surface ◽  
Nano Composites ◽  
Candida Spp ◽  
Nano Composite ◽  
Tooth Surfaces

Candida species including Candida albicans, Candida krusei and Candida glabrata are opportunistic microorganisms that inhabit oral cavity. The objective of this study is to determine the effect of dental caries on Candida spp. biofilm-forming ability on nano- composite with the hypothesis that dental caries enhances the colonization of Candida spp. To assess Candida spp. colonisation in the oral cavity of the paediatric patient, samples were obtained from 30 subjects aged five to six years old from Kuantan, Pahang, Malaysia. The samples were collected from buccal mucosa, palate and tooth surfaces using sterile swabs. 10 mL of patient’s saliva suspension was also collected. Following that, the samples were inoculated on CHROMagar and incubated for 24 h at 37 ºC. Candida biofilm of caries isolate C. albicans (HNFC2), and C. albicans ATCC 32354 were developed on three different types of nano-composites. The study showed that no C. albicans was isolated from the caries-free oral cavity while 76% of children with caries possessed Candida spp. 65% of the yeasts were isolated from the tooth surface. Only 35% of the total isolates were obtained from soft tissues, including palatal and buccal mucosa. C. albicans is the most isolated Candida spp. with 82% and 67% of the yeast were obtained from the tooth surface and buccal mucosa, respectively. Besides, HNFC2 significantly colonised the nano- composites more than the ATCC (P < 0.05). In the comparison of the three types of nano- composites, nano-hybrid-based containing pre-polymerised filler (cB) exhibited the least C. albicans HNFC2 cells colonisation with 7.7 x 10³ cells mL-1. In contrast, the nano-composite that contained bulk-filled nanohybrid (cC) was the most colonised with 14.3 x 10³ cells mL-1. In conclusion, dental caries enhances the colonization of Candida spp. in children's oral cavity, and that caries isolate form more biofilm on nano-composites compared to the lab strain C. albicans.

scholarly journals Aggregatibacter actinomycetemcomitans: The virulence factors and relation to persistence biofilm formation

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 429-435
Author(s):  
Syakir Syahiran ◽  
Wan Rohani Wan Taib ◽  
Norzawani Jaffar
Keyword(s):  
Oral Cavity ◽  
Virulence Factors ◽  
Tooth Loss ◽  
Periodontal Diseases ◽  
Aggregatibacter Actinomycetemcomitans ◽  
Aggressive Periodontitis ◽  
Essential Factor ◽  
Abiotic Surfaces ◽  
Functional Biology ◽  
Systemic Infections

Periodontitis is an infectious and inflammatory condition that is associated with subgingival biofilms in tooth-supporting tissues. Among the several hundred isolated organisms in the oral cavity, one of the most isolated bacteria from infected periodontal pockets are Aggregatibacter actinomycetemcomitans. It is a Gram-negative, facultative anaerobic bacillus that causes juvenile (localized aggressive periodontitis) and adolescent periodontal diseases. The development of biofilms is an essential factor in pathogenesis for A. actinomycetemcomitans. The early attachment of A. actinomycetemcomitans to abiotic surfaces relies on its protein-like fimbriae. This organism's ability to form tenacious biofilms can determine its survival and progression. A. actinomycetemcomitans, a pathogen not solely in periodontal but also involve in some systemic infections. This species has several virulence factors and genes that contribute to its oral cavity survival and, worst of all, cause bone resorption and tooth loss. Genetic diversity between the different A. actinomycetemcomitans isolates are great, and their ability to express and release virulence factors varies. In this review article, we discuss about the potential virulence factors and candidates genes for A. actinomycetemcomitans and their roles within periodontal disease by revealing their functional biology in facilitating attachment to oral surfaces, hindering protection of the host and causing inflammation and degradation of tissue.

Sign in / Sign up

Export Citation Format

Share Document