scholarly journals Near-infrared light-triggered synergistic antitumor therapy based on hollow ZIF-67-derived Co3S4-indocyanine green nanocomplex as a superior reactive oxygen species generator

Author(s):  
Ying Jiang ◽  
Yi Lu ◽  
Lingli Lei ◽  
Shengyu Zhou ◽  
Lu Yang ◽  
...  
ACS Nano ◽  
2014 ◽  
Vol 8 (7) ◽  
pp. 7260-7271 ◽  
Author(s):  
Liang Gao ◽  
Ru Liu ◽  
Fuping Gao ◽  
Yaling Wang ◽  
Xinglu Jiang ◽  
...  

2018 ◽  
Vol 6 (15) ◽  
pp. 2347-2357 ◽  
Author(s):  
Xuefei Zhang ◽  
Binyao Huang ◽  
Yifeng Shen ◽  
Chanzhen Yang ◽  
Zeqian Huang ◽  
...  

Nanoparticles with ROS-responsive properties could realize spatial and temporal drug release under NIR irradiation and the excess ROS could be used for PDT.


RSC Advances ◽  
2019 ◽  
Vol 9 (30) ◽  
pp. 17273-17280 ◽  
Author(s):  
Fan Yang ◽  
Jun Liu ◽  
Xue Jiang ◽  
Weiwei Wu ◽  
Zhenni Wang ◽  
...  

Photodynamic therapy (PDT) is a promising and effective method for tumor therapy that relies on the reactive oxygen species (ROS) produced by photosensitizers at specific wavelengths to inhibit tumor cells.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Shoupeng Cao ◽  
Jingxin Shao ◽  
Hanglong Wu ◽  
Shidong Song ◽  
Maria Teresa De Martino ◽  
...  

AbstractAggregation-induced emission (AIE) has, since its discovery, become a valuable tool in the field of nanoscience. AIEgenic molecules, which display highly stable fluorescence in an assembled state, have applications in various biomedical fields—including photodynamic therapy. Engineering structure-inherent, AIEgenic nanomaterials with motile properties is, however, still an unexplored frontier in the evolution of this potent technology. Here, we present phototactic/phototherapeutic nanomotors where biodegradable block copolymers decorated with AIE motifs can transduce radiant energy into motion and enhance thermophoretic motility driven by an asymmetric Au nanoshell. The hybrid nanomotors can harness two photon near-infrared radiation, triggering autonomous propulsion and simultaneous phototherapeutic generation of reactive oxygen species. The potential of these nanomotors to be applied in photodynamic therapy is demonstrated in vitro, where near-infrared light directed motion and reactive oxygen species induction synergistically enhance efficacy with a high level of spatial control.


2012 ◽  
Vol 48 (25) ◽  
pp. 3091 ◽  
Author(s):  
Yuichiro Koide ◽  
Mitsuyasu Kawaguchi ◽  
Yasuteru Urano ◽  
Kenjiro Hanaoka ◽  
Toru Komatsu ◽  
...  

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