Presynaptic nicotinic potentiation of a frog retinotectal transmission evoked by discharge of a single retina ganglion cell

2011 ◽  
Vol 70 (4) ◽  
pp. 391-400 ◽  
Author(s):  
Armantas Baginskas ◽  
Vilija Kuraite ◽  
Antanas Kuras
Keyword(s):  
Ganglion Cell ◽  
Retina Ganglion Cell ◽  
Retinotectal Transmission

scholarly journals Inhibition of Dendritic L-Type Calcium Current by Memantine in Frog Tectum

Medicina ◽  
2013 ◽  
Vol 49 (9) ◽  
pp. 64
Author(s):  
Armantas Baginskas ◽  
Antanas Kuras ◽  
Artūras Grigaliūnas
Keyword(s):  
Ganglion Cell ◽  
Calcium Current ◽  
Rana Temporaria ◽  
Neuroprotective Effect ◽  
Retinal Ganglion ◽  
Negative Wave ◽  
Current Pulses ◽  
Retina Ganglion Cell ◽  
Retinotectal Transmission

The aim of the study was to explore the effects of memantine on responses elicited in the frog tectum by the bursts of spikes of moderate strength of a single retina ganglion cell and to gain an insight about the effect of memantine on the L-type Ca2+ current. Material and Methods. The experiments were performed in vivo on adult frogs (Rana temporaria). An individual retina ganglion cell (or its retinotectal fiber) was stimulated by current pulses delivered through a multichannel stimulating electrode positioned on the retina. Responses to the discharge of a single retinal ganglion cell were recorded in the tectum by an extracellular carbonfiber microelectrode positioned in the terminal arborization of the retinotectal fiber in the tectum layer F. The solution of memantine (1-amino-3,5-dimethyladamantane) hydrochloride (30 or 45 μM) was applied onto the surface of the tectum by perfusion at a rate of 0.4 mL/min. Results. Memantine (30–45 μM) largely inhibited the L-type Ca2+ channel-mediated slow negative wave and late discharges seen in the tectum responses without any effect on fast synaptic retinotectal transmission. Conclusions. Our results suggest that the neuroprotective effect of memantine could arise not only through the inhibition of the NMDA receptor current but also through the suppression of the L-type Ca2+ current.

Retina ganglion cell/inner plexiform layer and peripapillary nerve fiber layer thickness in patients with acromegaly

2016 ◽  
Vol 37 (3) ◽  
pp. 591-598 ◽  
Author(s):  
Muhammed Şahin ◽  
Alparslan Şahin ◽  
Faruk Kılınç ◽  
Harun Yüksel ◽  
Zeynep Gürsel Özkurt ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Plexiform Layer ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Retina Ganglion Cell

scholarly journals Light Exposue Activates Retina Ganglion Cell Lysophosphatidic Acid Acyl Transferase and Phosphatidic Acid Phosphatase by a c-fos-Dependent Mechanism

2001 ◽  
Vol 73 (3) ◽  
pp. 1228-1235 ◽  
Author(s):  
G. A. de Arriba Zerpa ◽  
M. E. Guido ◽  
D. F. Bussolino ◽  
S. J. Pasquare ◽  
P. I. Castagnet ◽  
...  
Keyword(s):  
Acid Phosphatase ◽  
Phosphatidic Acid ◽  
Ganglion Cell ◽  
Lysophosphatidic Acid ◽  
Acyl Transferase ◽  
Phosphatidic Acid Phosphatase ◽  
Retina Ganglion Cell ◽  
Dependent Mechanism

scholarly journals Electrical coupling in the retina ganglion cell layer increases the dynamic range

2014 ◽  
Vol 15 (S1) ◽  
Author(s):  
Cesar A Celis ◽  
Rodrigo Publio ◽  
Antonio C Roque
Keyword(s):  
Ganglion Cell ◽  
Dynamic Range ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Electrical Coupling ◽  
Retina Ganglion Cell

scholarly journals Secreted Frizzled Related Proteins Modulate Pathfinding and Fasciculation of Mouse Retina Ganglion Cell Axons by Direct and Indirect Mechanisms

2015 ◽  
Vol 35 (11) ◽  
pp. 4729-4740 ◽  
Author(s):  
S. Marcos ◽  
F. Nieto-Lopez ◽  
A. Sandonis ◽  
M. J. Cardozo ◽  
F. Di Marco ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Mouse Retina ◽  
Retina Ganglion Cell ◽  
Related Proteins

scholarly journals Rac1 Selective Activation Improves Retina Ganglion Cell Survival and Regeneration

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e64350 ◽  
Author(s):  
Erika Lorenzetto ◽  
Michele Ettorre ◽  
Valeria Pontelli ◽  
Matteo Bolomini-Vittori ◽  
Silvia Bolognin ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Cell Survival ◽  
Selective Activation ◽  
Retina Ganglion Cell
Sign in / Sign up

Export Citation Format

Share Document