A MATHEMATICAL MODEL OF A RETINA GANGLION CELL’ RESPONSE TO CONTRAST EDGES

2011 ◽  
Keyword(s):  
Mathematical Model ◽  
Ganglion Cell ◽  
Cell Response ◽  
Retina Ganglion Cell

scholarly journals 3D-Printed pHEMA Materials for Topographical and Biochemical Modulation of Dorsal Root Ganglion Cell Response

2017 ◽  
Vol 9 (36) ◽  
pp. 30318-30328 ◽  
Author(s):  
Adina Badea ◽  
Joselle M. McCracken ◽  
Emily G. Tillmaand ◽  
Mikhail E. Kandel ◽  
Aaron W. Oraham ◽  
...  
Keyword(s):  
Dorsal Root Ganglion ◽  
Ganglion Cell ◽  
Cell Response ◽  
Dorsal Root ◽  
Biochemical Modulation ◽  
Dorsal Root Ganglion Cell ◽  
3D Printed

Cat retinal ganglion cell receptive-field alterations after 6-hydroxydopamine induced dopaminergic amacrine cell lesions

1985 ◽  
Vol 53 (6) ◽  
pp. 1431-1443 ◽  
Author(s):  
G. W. Maguire ◽  
E. L. Smith
Keyword(s):  
Receptive Field ◽  
Ganglion Cell ◽  
Cell Response ◽  
Amacrine Cell ◽  
Ganglion Cells ◽  
Response Functions ◽  
Endogenous Dopamine ◽  
Dopamine Content ◽  
Intensity Response ◽  
6 Hydroxydopamine

Optic tract single-unit recordings were used to study ganglion cell response functions of the intact cat eye after 6-hydroxydopamine (6-OHDA) lesioning of the dopaminergic amacrine cell (AC) population of the inner retina. The impairment of the dopaminergic AC was verified by high pressure-liquid chromatography (HPLC) with electrochemical detection of endogenous dopamine content and by [3H]dopamine high-affinity uptake; the dopaminergic ACs of the treated eyes demonstrated reduced endogenous dopamine content and reduced [3H]dopamine uptake compared with that of their matched controls. Normal appearing [3H]GABA and [3H]-glycine uptake in the treated retinas suggests the absence of any nonspecific action of the 6-OHDA on the neural retina. The impairment of the dopaminergic AC population was found to alter a number of response properties in off-center ganglion cells, but this impairment had only a modest effect on the on-center cells. An abnormally high proportion of the off-center ganglion cells in the 6-OHDA treated eyes possessed nonlinear, Y-type receptive fields. These cells also possessed shift-responses of greater than normal amplitude, altered intensity-response functions, reduced maintained activities, and more transient center responses. Of the on-center type cells, only the Y-type on-center cells were affected by 6-OHDA, possessing higher than normal maintained activities and altered intensity-response functions. The on-center X-cells were unaffected by 6-OHDA treatment. The dopaminergic AC of the photopically adapted cat retina therefore modulates a number of ganglion cell response properties and within the limits of this study is most prominent in off-center ganglion cell circuitry. When functioning normally, the dopaminergic AC of the cat's retina appears to make the receptive field of the off-center cell more sustained and may make its spatial summation characteristics more linear while adjusting the intensitive properties of neurons in both the on- and off-center pathways.

Retina ganglion cell/inner plexiform layer and peripapillary nerve fiber layer thickness in patients with acromegaly

2016 ◽  
Vol 37 (3) ◽  
pp. 591-598 ◽  
Author(s):  
Muhammed Şahin ◽  
Alparslan Şahin ◽  
Faruk Kılınç ◽  
Harun Yüksel ◽  
Zeynep Gürsel Özkurt ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Plexiform Layer ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Retina Ganglion Cell

scholarly journals A mathematical model of mast cell response to acupuncture needling

2013 ◽  
Vol 351 (3-4) ◽  
pp. 101-105 ◽  
Author(s):  
Yannick Deleuze
Keyword(s):  
Mathematical Model ◽  
Mast Cell ◽  
Cell Response
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