An fMRI-study on single-sided deafness: Spectral-temporal properties and side of stimulation modulates hemispheric dominance

Summary Objectives : In our previous functional magnetic resonance imaging (fMRI) study, we determined that there was distinct left hemispheric dominance for lexical- semantic processing without the influence of human voice perception in right-handed healthy subjects. However, the degree of right-handedness in the right-handed subjects ranged from 52 to 100 according to the Edinburgh Handedness Inventory (EHI) score. In the present study, we aimed to clarify the correlation between the degree of right-handedness and language dominance in the fronto-temporo-parietal cortices by examining cerebral activation for lexical-semantic processing. Methods : Twenty-seven normal right-handed healthy subjects were scanned by fMRI while listening to sentences (SEN), reverse sentences (rSEN), and identifiable non-vocal sounds (SND). Fronto-temporo-parietal activation was observed in the left hemisphere under the SEN - rSEN contrast, which included lexical- semantic processing without the influence of human voice perception. Laterality Indexwas calculated as LI = (L - R)/(L + R) X 100, L: left, R: right. Results : Laterality Index in the fronto-temporo-parietal cortices did not correlate with the degree of right-handedness in EHI score. Conclusions : The present study indicated that the degree of right-handedness from 52 to 100 in EHI score had no effect on the degree of left hemispheric dominance for lexical-semantic processing in right-handed healthy subjects.

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Left hemispheric dominance for „motor permanence“: An fMRI study

NeuroImage ◽

10.1016/s1053-8119(18)30954-6 ◽

1998 ◽

Vol 7 (4) ◽

pp. S121

Author(s):

G. Buccino ◽

F. Binkofski ◽

S. Posse ◽

K.M. Stephan ◽

H.-J. Freund ◽

...

Keyword(s):

Hemispheric Dominance ◽

Fmri Study

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Temporal properties of pain matrix: A event-related fMRI study

NeuroImage ◽

10.1016/s1053-8119(00)91685-9 ◽

2000 ◽

Vol 11 (5) ◽

pp. S755

Author(s):

Chiau-Fang Chen ◽

Jen-Chuen Hsieh

Keyword(s):

Pain Matrix ◽

Temporal Properties ◽

Fmri Study

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Horizontal or vertical optokinetic stimulation activates visual motion- sensitive, ocular motor and vestibular cortex areas with right hemispheric dominance. An fMRI study

Brain ◽

10.1093/brain/121.8.1479 ◽

1998 ◽

Vol 121 (8) ◽

pp. 1479-1495 ◽

Cited By ~ 113

Author(s):

M Dieterich

Keyword(s):

Visual Motion ◽

Hemispheric Dominance ◽

Optokinetic Stimulation ◽

Ocular Motor ◽

Vestibular Cortex ◽

Fmri Study

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Overt speech critically changes lateralization index and did not allow determination of hemispheric dominance for language: an fMRI study

BMC Neuroscience ◽

10.1186/s12868-021-00671-y ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

David Hassanein Berro ◽

Jean-Michel Lemée ◽

Louis-Marie Leiber ◽

Evelyne Emery ◽

Philippe Menei ◽

...

Keyword(s):

Resting State ◽

Cognitive Networks ◽

Hemispheric Dominance ◽

Dominant Hemisphere ◽

Rightward Shift ◽

Fmri Study ◽

Intrinsic Connectivity Networks ◽

Overt Speech ◽

Lateralization Index

Abstract Background Pre-surgical mapping of language using functional MRI aimed principally to determine the dominant hemisphere. This mapping is currently performed using covert linguistic task in way to avoid motion artefacts potentially biasing the results. However, overt task is closer to natural speaking, allows a control on the performance of the task, and may be easier to perform for stressed patients and children. However, overt task, by activating phonological areas on both hemispheres and areas involved in pitch prosody control in the non-dominant hemisphere, is expected to modify the determination of the dominant hemisphere by the calculation of the lateralization index (LI). Objective Here, we analyzed the modifications in the LI and the interactions between cognitive networks during covert and overt speech task. Methods Thirty-three volunteers participated in this study, all but four were right-handed. They performed three functional sessions consisting of (1) covert and (2) overt generation of a short sentence semantically linked with an audibly presented word, from which we estimated the “Covert” and “Overt” contrasts, and a (3) resting-state session. The resting-state session was submitted to spatial independent component analysis to identify language network at rest (LANG), cingulo-opercular network (CO), and ventral attention network (VAN). The LI was calculated using the bootstrapping method. Results The LI of the LANG was the most left-lateralized (0.66 ± 0.38). The LI shifted from a moderate leftward lateralization for the Covert contrast (0.32 ± 0.38) to a right lateralization for the Overt contrast (− 0.13 ± 0.30). The LI significantly differed from each other. This rightward shift was due to the recruitment of right hemispheric temporal areas together with the nodes of the CO. Conclusion Analyzing the overt speech by fMRI allowed improvement in the physiological knowledge regarding the coordinated activity of the intrinsic connectivity networks. However, the rightward shift of the LI in this condition did not provide the basic information on the hemispheric language dominance. Overt linguistic task cannot be recommended for clinical purpose when determining hemispheric dominance for language.

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The Neural Bases of Egocentric Spatial Representation for Extracorporeal and Corporeal Tasks: An fMRI Study

Brain Sciences ◽

10.3390/brainsci11080963 ◽

2021 ◽

Vol 11 (8) ◽

pp. 963

Author(s):

Stephanie Leplaideur ◽

Annelise Moulinet-Raillon ◽

Quentin Duché ◽

Lucie Chochina ◽

Karim Jamal ◽

...

Keyword(s):

Reference Frames ◽

Occipital Cortex ◽

Body Representation ◽

Hemispheric Dominance ◽

Midsagittal Plane ◽

Fmri Study ◽

Neural Bases ◽

Straight Ahead ◽

Healthy Participants ◽

Lateral Occipital Cortex

(1) Background: Humans use reference frames to elaborate the spatial representations needed for all space-oriented behaviors such as postural control, walking, or grasping. We investigated the neural bases of two egocentric tasks: the extracorporeal subjective straight-ahead task (SSA) and the corporeal subjective longitudinal body plane task (SLB) in healthy participants using functional magnetic resonance imaging (fMRI). This work was an ancillary part of a study involving stroke patients. (2) Methods: Seventeen healthy participants underwent a 3T fMRI examination. During the SSA, participants had to divide the extracorporeal space into two equal parts. During the SLB, they had to divide their body along the midsagittal plane. (3) Results: Both tasks elicited a parieto-occipital network encompassing the superior and inferior parietal lobules and lateral occipital cortex, with a right hemispheric dominance. Additionally, the SLB > SSA contrast revealed activations of the left angular and premotor cortices. These areas, involved in attention and motor imagery suggest a greater complexity of corporeal processes engaging body representation. (4) Conclusions: This was the first fMRI study to explore the SLB-related activity and its complementarity with the SSA. Our results pave the way for the exploration of spatial cognitive impairment in patients.

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The Effect of Nonlinear Amplitude Growth on the Speech Perception Benefits Provided by a Single-Sided Vocoder

Journal of Speech Language and Hearing Research ◽

10.1044/2018_jslhr-h-18-0001 ◽

2019 ◽

Vol 62 (3) ◽

pp. 745-757 ◽

Cited By ~ 2

Author(s):

Jessica M. Wess ◽

Joshua G. W. Bernstein

Keyword(s):

Transfer Functions ◽

Spatial Configuration ◽

Free Field ◽

Spatial Separation ◽

Compression And Expansion ◽

Interaural Difference ◽

Interaural Differences ◽

Single Sided Deafness ◽

Perceptual Separation ◽

Loudness Growth

PurposeFor listeners with single-sided deafness, a cochlear implant (CI) can improve speech understanding by giving the listener access to the ear with the better target-to-masker ratio (TMR; head shadow) or by providing interaural difference cues to facilitate the perceptual separation of concurrent talkers (squelch). CI simulations presented to listeners with normal hearing examined how these benefits could be affected by interaural differences in loudness growth in a speech-on-speech masking task.MethodExperiment 1 examined a target–masker spatial configuration where the vocoded ear had a poorer TMR than the nonvocoded ear. Experiment 2 examined the reverse configuration. Generic head-related transfer functions simulated free-field listening. Compression or expansion was applied independently to each vocoder channel (power-law exponents: 0.25, 0.5, 1, 1.5, or 2).ResultsCompression reduced the benefit provided by the vocoder ear in both experiments. There was some evidence that expansion increased squelch in Experiment 1 but reduced the benefit in Experiment 2 where the vocoder ear provided a combination of head-shadow and squelch benefits.ConclusionsThe effects of compression and expansion are interpreted in terms of envelope distortion and changes in the vocoded-ear TMR (for head shadow) or changes in perceived target–masker spatial separation (for squelch). The compression parameter is a candidate for clinical optimization to improve single-sided deafness CI outcomes.

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Auditory Training to Improve Speech Perception and Self-Efficacy in Aging Adults

Journal of Speech Language and Hearing Research ◽

10.1044/2019_jslhr-19-00355 ◽

2020 ◽

Vol 63 (4) ◽

pp. 1270-1281

Author(s):

Leah Fostick ◽

Riki Taitelbaum-Swead ◽

Shulamith Kreitler ◽

Shelly Zokraut ◽

Miriam Billig

Keyword(s):

Speech Perception ◽

Self Efficacy ◽

Temporal Order Judgment ◽

Auditory Training ◽

Intensity Discrimination ◽

Training Design ◽

Auditory Temporal Processing ◽

Temporal Properties ◽

Computer Based ◽

Aging Adults

Purpose Difficulty in understanding spoken speech is a common complaint among aging adults, even when hearing impairment is absent. Correlational studies point to a relationship between age, auditory temporal processing (ATP), and speech perception but cannot demonstrate causality unlike training studies. In the current study, we test (a) the causal relationship between a spatial–temporal ATP task (temporal order judgment [TOJ]) and speech perception among aging adults using a training design and (b) whether improvement in aging adult speech perception is accompanied by improved self-efficacy. Method Eighty-two participants aged 60–83 years were randomly assigned to a group receiving (a) ATP training (TOJ) over 14 days, (b) non-ATP training (intensity discrimination) over 14 days, or (c) no training. Results The data showed that TOJ training elicited improvement in all speech perception tests, which was accompanied by increased self-efficacy. Neither improvement in speech perception nor self-efficacy was evident following non-ATP training or no training. Conclusions There was no generalization of the improvement resulting from TOJ training to intensity discrimination or generalization of improvement resulting from intensity discrimination training to speech perception. These findings imply that the effect of TOJ training on speech perception is specific and such improvement is not simply the product of generally improved auditory perception. It provides support for the idea that temporal properties of speech are indeed crucial for speech perception. Clinically, the findings suggest that aging adults can be trained to improve their speech perception, specifically through computer-based auditory training, and this may improve perceived self-efficacy.

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