P.256Steroid treatment may change natural history in young children with LMNA mutations and dropped head syndrome

2019 ◽  
Vol 29 ◽  
pp. S141
Author(s):  
M. Gomez Garcia de la Banda ◽  
D. Natera-De Benito ◽  
I. Dabaj ◽  
R. Ben Yaou ◽  
C. Ortez ◽  
...  
Hematology ◽  
2018 ◽  
Vol 2018 (1) ◽  
pp. 405-411 ◽  
Author(s):  
Jenny M. Despotovic ◽  
Amanda B. Grimes

Abstract Immune thrombocytopenia (ITP) has historically been thought to occur in 2 distinct forms: childhood ITP and adult ITP. This division is based largely on the presumption that childhood ITP is often benign and self-limited, whereas ITP in adults tends to be more chronic and difficult to treat. Although data exist to justify a different approach to the diagnosis and treatment in young children and the elderly, ITP in older children, adolescents, and younger adults is likely to share more similar pathology. This article will highlight the most recent data describing the natural history, diagnostic approach, management strategies, and disease-related outcomes in children and adults with ITP. These data reveal many unexpected similarities between the 2 groups, while confirming some of the more well-described differences. Discussion of these findings aims to highlight similarities and differences between ITP in children and adults, which will underscore important areas of future research and/or changes in management guidelines.


2000 ◽  
Vol 137 (6) ◽  
pp. 749-755 ◽  
Author(s):  
Timothy K. Vander Leek ◽  
Andrew H. Liu ◽  
Kay Stefanski ◽  
Betty Blacker ◽  
S.Allan Bock

1996 ◽  
Vol 39 ◽  
pp. 132-132 ◽  
Author(s):  
Howard Faden ◽  
Linda Duffy ◽  
Ray Wasielewski ◽  
Ying Tung

2018 ◽  
Vol 16 (3) ◽  
pp. 369-382 ◽  
Author(s):  
Elaine Bates

Recent studies indicate that contact with nature is important for children’s development, and supports creativity, wellbeing, problem solving and empathy with nature as adults. Researchers raise concerns that this experience is being eroded by a decline in green spaces (especially in cities) and an increasingly risk averse society (Bragg et al.2013; Louv 2005; Moss 2012; Pretty et al. 2009).Whilst direct experiences of nature may be increasingly rare for young children, Kellert’s work on biophilia and child development (2005) suggests that indirect experiences with nature, such as those occurring during a museum visit, may be able to compensate for this. Within this context, Manchester Museum developed Nature Discovery (opened in December 2014), a gallery aimed at engaging under-5s and their parents with nature. As well as drawing from existing studies of young children in museums, the gallery responded to research carried out with local parents, young children and teachers. This research focused on documenting parent and child interactions during a series of child-led, family visits to the existing natural history galleries and further visits by different families to evaluate the new gallery (2015).Using existing nature connection measures (Cheng and Munro 2012; Ernst and Theimer 2011), the results suggest that natural history objects can support a connection to nature, which may result in environmentally friendly behaviours in adulthood. Parent and child interaction is identified as a key characteristic of supporting a connection to nature and in supporting children’s learning.


2014 ◽  
Vol 77 (1) ◽  
pp. 166-169 ◽  
Author(s):  
Saif F. Hassan ◽  
Stephen M. Cohn ◽  
John Admire ◽  
Olliver Nunez-Cantu ◽  
Yousef Arar ◽  
...  

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