The use of zebrafish (Danio rerio) as a model system in neurobehavioral toxicology

2004 ◽  
Vol 26 (6) ◽  
pp. 707-708 ◽  
Author(s):  
Frank M. Scalzo ◽  
Edward D. Levin
Keyword(s):  
Danio Rerio ◽  
Model System

scholarly journals Dietary Strontium Increases Bone Mineral Density in Intact Zebrafish (Danio rerio): A Potential Model System for Bone Research

Zebrafish ◽  
2010 ◽  
Vol 7 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Anthony J. Siccardi ◽  
Steve Padgett-Vasquez ◽  
Heath W. Garris ◽  
Tim R. Nagy ◽  
Louis R. D'Abramo ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Danio Rerio ◽  
Potential Model ◽  
Model System ◽  
Mineral Density ◽  
Bone Research

scholarly journals The fish watch: Zebrafish: a clock in every cell

2005 ◽  
Vol 27 (6) ◽  
pp. 23-26
Author(s):  
Amanda-Jayne F. Carr ◽  
David Whitmore
Keyword(s):  
Circadian Rhythms ◽  
Danio Rerio ◽  
Biological Process ◽  
Genetic Model ◽  
Model System ◽  
Biological Processes ◽  
Powerful Method ◽  
Dark Cycle ◽  
Environmental Light ◽  
The One

The environmental light–dark cycle is one of the most reliable rhythmic signals, and many organisms have evolved a circadian (circa diem, ‘about a day’) system to co-ordinate biological processes with this predictable environmental change. These rhythms are endogenous and persist even in constant conditions, the light–dark cycle serving to synchronize these rhythms precisely to 24 hours. Genetic approaches have proved invaluable in increasing our understanding of the circadian clock. The ability to isolate a mutant with a defect in a rhythmic process is a very powerful method, which depends on no prior assumptions about the biological process under investigation. Consequently, Drosophila and the mouse have become the most powerful genetic models to study circadian rhythms in animals. The one alternative vertebrate genetic model system to the mouse is the zebrafish (Danio rerio).

Developmental toxicity of trichloroethylene in zebrafish (Danio rerio)

2020 ◽  
Vol 22 (3) ◽  
pp. 728-739 ◽  
Author(s):  
Katharine A. Horzmann ◽  
Ana M. Portales ◽  
Kathryn G. Batcho ◽  
Jennifer L. Freeman
Keyword(s):  
Heart Rate ◽  
Danio Rerio ◽  
Developmental Toxicity ◽  
Model System ◽  
Embryonic Exposure ◽  
System P ◽  
And Behavior

Embryonic exposure to ecologically relevant concentrations of TCE disrupts development, morphology, heart rate, and behavior in the zebrafish (Danio rerio) model system.

Behavioral toxicity of tannery effluent in zebrafish (Danio rerio) used as model system

2019 ◽  
Vol 685 ◽  
pp. 923-933 ◽  
Author(s):  
Thales Quintão Chagas ◽  
Tenilce Gabriela da Silva Alvarez ◽  
Mateus Flores Montalvão ◽  
Carlos Mesak ◽  
Thiago Lopes Rocha ◽  
...  
Keyword(s):  
Danio Rerio ◽  
Model System ◽  
Tannery Effluent ◽  
Behavioral Toxicity

scholarly journals Homology-Modeled Ligand-Binding Domains of Zebrafish Estrogen Receptors α, β1, and β2: From in Silico to in Vivo Studies of Estrogen Interactions in Danio rerio as a Model System

2005 ◽  
Vol 19 (12) ◽  
pp. 2979-2990 ◽  
Author(s):  
Aurora D. Costache ◽  
Phani Kumar Pullela ◽  
Purnachandar Kasha ◽  
Henry Tomasiewicz ◽  
Daniel S. Sem
Keyword(s):  
Ligand Binding ◽  
Estrogen Receptors ◽  
Danio Rerio ◽  
In Silico ◽  
Model System ◽  
In Vivo Studies ◽  
Binding Domains

The Zebrafish (Danio rerio): A Model System for Cranial Suture Patterning

2005 ◽  
Vol 181 (2) ◽  
pp. 109-118 ◽  
Author(s):  
Natalina Quarto ◽  
Michael T. Longaker
Keyword(s):  
Danio Rerio ◽  
Model System ◽  
Cranial Suture

Dissecting metabolism using zebrafish models of disease

2019 ◽  
Vol 47 (1) ◽  
pp. 305-315 ◽  
Author(s):  
Talhah M. Salmi ◽  
Vicky W. T. Tan ◽  
Andrew G. Cox
Keyword(s):  
Liver Disease ◽  
Danio Rerio ◽  
Fatty Liver Disease ◽  
Model Organism ◽  
Model System ◽  
Genetic Screens ◽  
Zebrafish Model ◽  
High Fecundity ◽  
Models Of Disease

Abstract Zebrafish (Danio rerio) are becoming an increasingly powerful model organism to study the role of metabolism in disease. Since its inception, the zebrafish model has relied on unique attributes such as the transparency of embryos, high fecundity and conservation with higher vertebrates, to perform phenotype-driven chemical and genetic screens. In this review, we describe how zebrafish have been used to reveal novel mechanisms by which metabolism regulates embryonic development, obesity, fatty liver disease and cancer. In addition, we will highlight how new approaches in advanced microscopy, transcriptomics and metabolomics using zebrafish as a model system have yielded fundamental insights into the mechanistic underpinnings of disease.

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