Bradykinin and kallidin levels in the trapezius muscle in patients with work-related trapezius myalgia, in patients with whiplash associated pain, and in healthy controls – A microdialysis study of women

Pain ◽  
2008 ◽  
Vol 139 (3) ◽  
pp. 578-587 ◽  
Author(s):  
Björn Gerdle ◽  
Ulrich Hilgenfeldt ◽  
Britt Larsson ◽  
Jesper Kristiansen ◽  
Karen Søgaard ◽  
...  
Keyword(s):  
Trapezius Muscle ◽  
Healthy Controls ◽  
Work Related ◽  
Trapezius Myalgia ◽  
Microdialysis Study

Biomarkers alterations in trapezius muscle after an acute tissue trauma: A human microdialysis study

2017 ◽  
Vol 16 (1) ◽  
pp. 184
Author(s):  
L.B. Sørensen ◽  
P. Gazerani ◽  
K. Wåhlén ◽  
N. Ghafouri ◽  
B. Gerdle ◽  
...  
Keyword(s):  
Trapezius Muscle ◽  
Healthy Controls ◽  
Tibialis Muscle ◽  
Pressure Pain Thresholds ◽  
Potential Case ◽  
Gender Based ◽  
Microdialysis Study ◽  
Tissue Trauma ◽  
Real Time Information ◽  
Metabolic Biomarkers

AbstractAimsAlteration in muscle milieu has been proposed as one of the main contributors underlying chronic musculoskeletal pain (CMP). Microdialysis (MD) provides real-time information on release of pain and metabolic biomarkers in muscle. However, insertion of MD probe causes a local tissue trauma, which may affect the tissue milieu. Whether an acute tissue trauma alter pain and metabolite biomarkers in trapezius muscle of patients with CMP is not known. Hence, this study investigated changes in muscle metabolites following MD probe insertion in patients with CMP in comparison with healthy controls.MethodsNineteen patients (11 women and 8 men; 41.4 years) with CMP and 20 pain-free volunteers (10 women and 10 men; 36.5 years) were recruited (project approval number: 2013/151- 31). Baseline pressure pain thresholds (PPT) at trapezius muscle were obtained bilaterally with a reference point at the tibialis muscle. Pain questionnaires were used for determining levels of anxiety and depression and catastrophizing impact. Interstitial samples were collected from trapezius muscles by aid of MD (20 kDa cut-off) during a period of 40 min. Collected dialysates at 2 time-points of 20 and 40 min were stored at −70 °C until analysis. Concentrations of glucose, lactate, pyruvate, glycerol, and glutamate were analyzed by ISCUSSflex. P ≤ 0.05 was considered significant.ResultsNo potential case with respect to anxiety, depression or catastrophizing impact was found. Lower PPTs were found in CMP group (P ≤ 0.05). Significantly lower levels of pyruvate were found in CMP group at both 20 min (P = 0.003) and 40 min (P = 0.006). Gender-based analysis indicated higher concentrations of glutamate in female patients with CMP.ConclusionsThis study was first to demonstrate metabolite alterations during trauma phase of MD in trapezius muscles of CPM compared with healthy controls. This model proved beneficial for investigating pain and metabolic biomarkers during acute phase of MD.

391 BRADYKININ AND KALLIDIN LEVELS ARE INCREASED IN TRAPEZIUS MUSCLE OF PATIENTS WITH TRAPEZIUS MYALGIA BUT NOT WAD-PATIENTS OR HEALTHY CONTROLS

2006 ◽  
Vol 10 (S1) ◽  
pp. S104c-S105
Author(s):  
L. Rosendal ◽  
B. Gerdle ◽  
B. Larsson ◽  
J. Kristiansen ◽  
K. Søgaard ◽  
...  
Keyword(s):  
Trapezius Muscle ◽  
Healthy Controls ◽  
Trapezius Myalgia

scholarly journals High-Intensity Strength Training Improves Function of Chronically Painful Muscles: Case-Control and RCT Studies

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Lars L. Andersen ◽  
Christoffer H. Andersen ◽  
Jørgen H. Skotte ◽  
Charlotte Suetta ◽  
Karen Søgaard ◽  
...  
Keyword(s):  
Strength Training ◽  
Muscle Fiber ◽  
High Intensity ◽  
Case Control Study ◽  
Trapezius Muscle ◽  
Case Control ◽  
Healthy Controls ◽  
Trapezius Myalgia ◽  
Strength Capacity ◽  
Control Study

Aim. This study investigates consequences of chronic neck pain on muscle function and the rehabilitating effects of contrasting interventions.Methods. Women with trapezius myalgia (MYA,n=42) and healthy controls (CON,n=20) participated in a case-control study. Subsequently MYA were randomized to 10 weeks of specific strength training (SST,n=18), general fitness training (GFT,n=16), or a reference group without physical training (REF,n=8). Participants performed tests of 100 consecutive cycles of 2 s isometric maximal voluntary contractions (MVC) of shoulder elevation followed by 2 s relaxation at baseline and 10-week follow-up.Results. In the case-control study, peak force, rate of force development, and rate of force relaxation as well as EMG amplitude were lower in MYA than CON throughout all 100 MVC. Muscle fiber capillarization was not significantly different between MYA and CON. In the intervention study, SST improved all force parameters significantly more than the two other groups, to levels comparable to that of CON. This was seen along with muscle fiber hypertrophy and increased capillarization.Conclusion. Women with trapezius myalgia have lower strength capacity during repetitive MVC of the trapezius muscle than healthy controls. High-intensity strength training effectively improves strength capacity during repetitive MVC of the painful trapezius muscle.

Generalized Neck-Shoulder Hyperalgesia in Chronic Tension-Type Headache and Unilateral Migraine Assessed by Pressure Pain Sensitivity Topographical Maps of the Trapezius Muscle

Cephalalgia ◽  
2009 ◽  
Vol 30 (1) ◽  
pp. 77-86 ◽  
Author(s):  
C Fernández-de-las-Peñas ◽  
P Madeleine ◽  
AB Caminero ◽  
ML Cuadrado ◽  
L Arendt-Nielsen ◽  
...  
Keyword(s):  
Pain Sensitivity ◽  
Trapezius Muscle ◽  
Tension Type Headache ◽  
Healthy Controls ◽  
Pressure Pain ◽  
Chronic Tension Type Headache ◽  
Pressure Pain Thresholds ◽  
Pressure Algometer ◽  
Type Headache ◽  
Topographical Maps

Spatial changes in pressure pain hypersensitivity are present throughout the cephalic region (temporalis muscle) in both chronic tension-type headache (CTTH) and unilateral migraine. The aim of this study was to assess pressure pain sensitivity topographical maps on the trapezius muscle in 20 patients with CTTH and 20 with unilateral migraine in comparison with 20 healthy controls in a blind design. For this purpose, a pressure algometer was used to assess pressure pain thresholds (PPT) over 11 points of the trapezius muscle: four points in the upper part of the muscle, two over the levator scapulae muscle, two in the middle part, and the remaining three points in the lower part of the muscle. Pressure pain sensitivity maps of both sides (dominant/non-dominant; symptomatic/non-symptomatic) were depicted for patients and controls. CTTH patients showed generalized lower PPT levels compared with both migraine patients ( P = 0.03) and controls ( P < 0.001). The migraine group had also lower PPT than healthy controls ( P < 0.001). The most sensitive location for the assessment of PPT was the neck portion of the upper trapezius muscle in both patient groups and healthy controls ( P < 0.001). PPT was negatively related to some clinical pain features in both CTTH and unilateral migraine patients (all P < 0.05). Side-to-side differences were found in strictly unilateral migraine, but not in those subjects with bilateral pain, i.e. CTTH. These data support the influence of muscle hyperalgesia in both CTTH and unilateral migraine patients and point towards a general pressure pain hyperalgesia of neck-shoulder muscles in headache patients, particularly in CTTH.

Changes in Trapezius Muscle Structure in Fibromyalgia and Chronic Trapezius Myalgia

1993 ◽  
Vol 1 (3-4) ◽  
pp. 171-176 ◽  
Author(s):  
Rolf Lindman ◽  
Mats Hagberg ◽  
Ann Bengtsson ◽  
K. G. Henricksson ◽  
Lars-Eric Thornell
Keyword(s):  
Trapezius Muscle ◽  
Muscle Structure ◽  
Trapezius Myalgia

scholarly journals Muscle Activation During Selected Strength Exercises in Women With Chronic Neck Muscle Pain

2008 ◽  
Vol 88 (6) ◽  
pp. 703-711 ◽  
Author(s):  
Lars L Andersen ◽  
Michael Kjær ◽  
Christoffer H Andersen ◽  
Peter B Hansen ◽  
Mette K Zebis ◽  
...  
Keyword(s):  
Clinical Diagnosis ◽  
Muscle Pain ◽  
Muscle Activation ◽  
Trapezius Muscle ◽  
Emg Activity ◽  
Neck Muscle ◽  
Electromyographic Activity ◽  
Trapezius Myalgia ◽  
Shoulder Muscles ◽  
Strength Exercises

Background and PurposeMuscle-specific strength training has previously been shown to be effective in the rehabilitation of chronic neck muscle pain in women. The aim of this study was to determine the level of activation of the neck and shoulder muscles using surface electromyography (EMG) during selected strengthening exercises in women undergoing rehabilitation for chronic neck muscle pain (defined as a clinical diagnosis of trapezius myalgia).SubjectsThe subjects were 12 female workers (age=30–60 years) with a clinical diagnosis of trapezius myalgia and a mean baseline pain intensity of 5.6 (range=3–8) on a scale of 0 to 9.MethodElectromyographic activity in the trapezius and deltoid muscles was measured during the exercises (lateral raises, upright rows, shrugs, one-arm rows, and reverse flys) and normalized to EMG activity recorded during a maximal voluntary static contraction (MVC).ResultsFor most exercises, the level of muscle activation was relatively high (&gt;60% of MVC), highlighting the effectiveness and specificity of the respective exercises. For the trapezius muscle, the highest level of muscle activation was found during the shrug (102±11% of MVC), lateral raise (97±6% of MVC), and upright row (85±5% of MVC) exercises, but the latter 2 exercises required smaller training loads (3–10 kg) compared with the shrug exercise (20–30 kg).Discussion and ConclusionThe lateral raise and upright row may be suitable alternatives to shrugs during rehabilitation of chronic neck muscle pain. Several of the strength exercises had high activation of neck and shoulder muscles in women with chronic neck pain. These exercises can be used equally in the attempt to achieve a beneficial treatment effect on chronic neck muscle pain.

Sign in / Sign up

Export Citation Format

Share Document