Intercountry differences in dyskinesia in advanced- vs non-advanced Parkinson's disease: a post hoc analysis of the OBSERVE-PD observational study

2020 ◽  
Vol 79 ◽  
pp. e39
Author(s):  
A. Fasano ◽  
L. Bergmann ◽  
V.S. Fung ◽  
K. Onuk ◽  
K. Seppi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Observational Study ◽  
Advanced Parkinson’S Disease ◽  
Post Hoc Analysis ◽  
Post Hoc

scholarly journals The “Gender Factor” in Wearing-Off among Patients with Parkinson’s Disease: A Post Hoc Analysis of DEEP Study

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Delia Colombo ◽  
Giovanni Abbruzzese ◽  
Angelo Antonini ◽  
Paolo Barone ◽  
Gilberto Bellia ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cross Sectional Study ◽  
Motor Symptom ◽  
Cross Sectional ◽  
Post Hoc Analysis ◽  
Increased Risk ◽  
Wearing Off ◽  
Gender Factor ◽  
Post Hoc

Background. The early detection of wearing-off in Parkinson disease (DEEP) observational study demonstrated that women with Parkinson’s disease (PD) carry an increased risk (80.1%) for wearing-off (WO). This post hoc analysis of DEEP study evaluates gender differences on WO and associated phenomena.Methods. Patients on dopaminergic treatment for ≥1 year were included in this multicenter observational cross-sectional study. In a single visit, WO was diagnosed based on neurologist assessment as well as the use of the 19-item wearing-off questionnaire (WOQ-19); WO was defined for scores ≥2. Post hoc analyses were conducted to investigate gender difference for demographic and clinical features with respect to WO.Results. Of 617 patients enrolled, 236 were women and 381 were men. Prevalence of WO was higher among women, according to both neurologists’ judgment (61.9% versus 53.8%,P=0.045) and the WOQ-19 analysis (72.5% versus 64.0%,P=0.034). In patients with WO (WOQ-19), women experienced ≥1 motor symptom in 72.5% versus 64.0% in men and ≥1 nonmotor symptom in 44.5% versus 36.7%, in men.Conclusions. Our results suggest WO as more common among women, for both motor and nonmotor symptoms. Prospective studies are warranted to investigate this potential gender-effect.

Rotigotine Transdermal System Improves Pain in Patients with Parkinson's Disease: A Post-Hoc Analysis of Patients Reporting Pain in the RECOVER Study (P06.085)

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. P06.085-P06.085
Author(s):  
T. Zesiewicz ◽  
O. Rascol ◽  
J. Friedman ◽  
E. Surmann ◽  
B. Boroojerdi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Post Hoc Analysis ◽  
Rotigotine Transdermal System ◽  
Post Hoc

Associations between Severity of Motor Function and Nonmotor Symptoms in Parkinson's Disease: A Post Hoc Analysis of the RECOVER Study

2014 ◽  
Vol 71 (3-4) ◽  
pp. 140-147 ◽  
Author(s):  
Todd J. Swick ◽  
Joseph H. Friedman ◽  
K. Ray Chaudhuri ◽  
Erwin Surmann ◽  
Babak Boroojerdi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor Function ◽  
Nonmotor Symptoms ◽  
Post Hoc Analysis ◽  
Post Hoc
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