Aerobic exercise improves bimanual coordination in Parkinson's disease: Response to Samuel and colleagues 2021

2021 ◽  
Author(s):  
A. Elizabeth Jansen ◽  
Mandy Miller Koop ◽  
Anson B. Rosenfeldt ◽  
Jay L. Alberts
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Bimanual Coordination ◽  
Disease Response

Subcutaneous apomorphine in parkinson's disease: Response to chronic administration for up to five years

1993 ◽  
Vol 8 (2) ◽  
pp. 165-170 ◽  
Author(s):  
A. J. Hughes ◽  
Susan Bishop ◽  
Birgit Kleedorfer ◽  
Nora Turjanski ◽  
W. Fernandez ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Chronic Administration ◽  
Disease Response ◽  
Subcutaneous Apomorphine

scholarly journals Aerobic Exercise and Healthy Nutrition as Neuroprotective Agents for Brain Health in Patients with Parkinson’s Disease: A Critical Review of the Literature

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 380
Author(s):  
Davide Maria Cammisuli ◽  
Ubaldo Bonuccelli ◽  
Simona Daniele ◽  
Claudia Martini ◽  
Jonathan Fusi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Cognitive Outcomes ◽  
Neuroprotective Agents ◽  
Brain Health ◽  
Beneficial Effects ◽  
Healthy Nutrition ◽  
Different Levels

Parkinson’s disease (PD) is characterized by motor and nonmotor features that have an influence on patients’ quality of life at different levels. To date, some evidences have arisen on the effectiveness of physical trainings and nutrients intake in ameliorating functional and cognitive outcomes in PD patients. Physical activity is effective in improving both motor and nonmotor features and recent epidemiological investigations have revealed the pivotal role that dietary patterns may play in reducing the risk of PD highlighting the pathogenesis of the neurodegeneration. Specifically, aerobic exercise shows beneficial effects in improving motor functions and executive control in PD patients, as well as proper nutrition may help in improving neuroprotective agents counteracting neurodegeneration and allows patients to better interact with the medication. Our narrative review critically focused on aerobic exercise and nutrition in PD in order to point out the best prescriptions for brain health of affected patients. Implications for a therapeutic plan and rehabilitation for these patients are also discussed.

Aerobic exercise intervention improves aerobic capacity and movement initiation in Parkinson's disease patients

2002 ◽  
Vol 17 (2) ◽  
pp. 161-168 ◽  
Author(s):  
John L. Bergen ◽  
Tonya Toole ◽  
Robert G. Elliott III ◽  
Brian Wallace ◽  
Keith Robinson ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Aerobic Capacity ◽  
Exercise Intervention ◽  
Movement Initiation

scholarly journals The Universal Prescription for Parkinson’s Disease: Exercise

2020 ◽  
Vol 10 (s1) ◽  
pp. S21-S27
Author(s):  
Jay L. Alberts ◽  
Anson B. Rosenfeldt
Keyword(s):  
Parkinson’S Disease ◽  
Heart Rate ◽  
Parkinson's Disease ◽  
Clinical Trials ◽  
Aerobic Exercise ◽  
Animal Studies ◽  
Clinical Findings ◽  
Patient Specific ◽  
Functional Changes ◽  
Beneficial Effects

Over the past two decades, aerobic exercise has emerged as a mainstream recommendation to aid in treating Parkinson’s disease (PD). Despite the acknowledgement of the benefits of exercise for people with PD (PwPD), frequently, exercise recommendations lack specificity in terms of frequency, intensity and duration. Additionally, conflating physical activity with exercise has contributed to providing vague exercise recommendations to PwPD. Therefore, the beneficial effects of exercise may not be fully realized in PwPD. Data provided by animal studies and select human trials indicate aerobic exercise may facilitate structural and functional changes in the brain. Recently, several large human clinical trials have been completed and collectively support the use of aerobic exercise, specifically high-intensity aerobic exercise, in improving PD motor symptoms. Data from these and other studies provide the basis to include aerobic exercise as an integral component in treating PD. Based on positive clinical findings and trials, it is advised that PwPD perform aerobic exercise in the following dose: 3x/week, 30–40-minute main exercise set, 60–80% of heart rate reserve or 70–85% of heart rate max. In lieu of heart rate, individuals can achieve an intensity of 14–17 on a 20-point RPE scale. Ongoing clinical trials, SPARX3 and CYCLE-II, have potential to further develop patient-specific exercise recommendations through prognostic modeling.

scholarly journals Rationale and Design of the PAIRED Trial: Partnered Dance Aerobic Exercise as a Neuroprotective, Motor, and Cognitive Intervention in Parkinson's Disease

2020 ◽  
Vol 11 ◽  
Author(s):  
Madeleine E. Hackney ◽  
Allison A. Bay ◽  
Jordan M. Jackson ◽  
Joe R. Nocera ◽  
Venkatagiri Krishnamurthy ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Cognitive Intervention ◽  
Paired Trial

scholarly journals Effect of Exercise on Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Kui Chen ◽  
Yan Tan ◽  
You Lu ◽  
Jiayan Wu ◽  
Xueyuan Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Subgroup Analysis ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Exercise Interventions

Background. Exercise has an integral impact on the physical and mental wellbeing of patients with Parkinson’s disease (PD), yet no comprehensive and quantitative analysis has been conducted on the effect of exercise on quality of life (QoL) in these patients. This study aimed to evaluate the effect of exercise on overall QoL and different domains of QoL in people with PD, as well as investigating the influence of factors such as the exercise type and intervention period. Methods. Databases, such as PubMed, Embase, and Cochrane Central Register of Controlled Trials, were searched since inception to August 14, 2018 to identify randomized controlled trials that compare the effect of exercise versus no intervention on QoL in PD patients. Following the subgroup analysis, heterogeneity was further explored. The quality of eligible studies was assessed according to PRISMA guidelines. Results. 20 studies were included with 1,143 participants in total. A meta-analysis showed a significant improvement in QoL after exercise intervention in PD patients (SMD = −0.24, 95% CI = −0.36 to −0.12, P<0.001). A subgroup analysis of exercise types revealed significant QoL improvement with aerobic exercise, martial arts, and dance, but not anaerobic exercise and combined exercise. Interventions lasting 12 weeks or longer improved QoL significantly. Conclusions. Exercise interventions, especially aerobic exercise, dance, and Tai Chi, significantly improve QoL in PD patients. At least 12 weeks of exercise is needed to bring about significant benefits.

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