In vitro and in vivo effects of some pesticides on carbonic anhydrase enzyme from rainbow trout (Oncorhynchus mykiss) gills

2010 ◽  
Vol 97 (3) ◽  
pp. 177-181 ◽  
Author(s):  
Saltuk Buğrahan Ceyhun ◽  
Murat Şentürk ◽  
Orhan Erdoğan ◽  
Ömer İrfan Küfrevioğlu
2004 ◽  
Vol 52 (4) ◽  
pp. 413-422 ◽  
Author(s):  
Ş. Aras-Hisar ◽  
O. Hisar ◽  
Ş. Beydemir ◽  
I. Gülçin ◽  
T. Yanik

Considering that the excessive usage of vitamin E causes hypervitaminosis and thus reduces blood erythrocyte concentrations, therefore it is worth studying how its pharmacological dosage affects the activity of carbonic anhydrase (CA) enzyme found in erythrocytes of rainbow trout (Oncorhynchus mykiss) in vitro and in vivo. Vitamin E inhibited CA enzyme and the IC50 value of the vitamin was 0.039 mM in vitro. Similarly, it was seen that vitamin E inhibited CA enzyme activity after the first hour following vitamin E injections in vivo. The activities of CA in groups of trout given vitamin E injection were measured at 1, 3 and 5 h and the corresponding activities were found to be 772.7 ± 290.5 (P < 0.05), 1286.4 ± 378.2 and 1005.7 ± 436.1 enzyme units (EU) g Hb-1. The difference over the control was significant (P < 0.05) in the first hour and insignificant at 3 and 5 h (P ? 0.05). The activity of CA in the control, which did not contain vitamin E, was determined as 1597.7 ± 429.0 EU g Hb-1.


2017 ◽  
Vol 98 (2) ◽  
pp. 559-565 ◽  
Author(s):  
Ali Ehsani ◽  
Mohammad Sedigh Jasour ◽  
Naser Agh ◽  
Mohammad Hashemi ◽  
Mahdi Khodadadi

2011 ◽  
Vol 27 (10) ◽  
pp. 573-582 ◽  
Author(s):  
Abigail E. Bartram ◽  
Matthew J. Winter ◽  
Duane B. Huggett ◽  
Paul McCormack ◽  
Lisa A. Constantine ◽  
...  

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