Luteolin attenuates Fipronil-induced neurotoxicity through reduction of the ROS-mediated oxidative stress in rat brain mitochondria

2021 ◽  
pp. 104785
Author(s):  
Enayatollah Seydi ◽  
Leila Mehrpouya ◽  
Hadiseh Sadeghi ◽  
Shabnam Rahimi ◽  
Jalal Pourahmad
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Rat Brain Mitochondria

Protection against malathion-induced oxidative stress in rat brain mitochondria by phosphodiesterase (PDE) type 4 selective inhibitor

2009 ◽  
Vol 189 ◽  
pp. S215
Author(s):  
Mohammad-Ali Rezvanfar ◽  
Mohammad Amin Rezvanfar ◽  
Akram Ranjbar ◽  
Mohammad Abdollahi
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Brain Mitochondria ◽  
Selective Inhibitor ◽  
Rat Brain Mitochondria

Depleted uranium induces disruption of energy homeostasis and oxidative stress in isolated rat brain mitochondria

Metallomics ◽  
2013 ◽  
Vol 5 (6) ◽  
pp. 736 ◽  
Author(s):  
Fatemeh Shaki ◽  
Mir-Jamal Hosseini ◽  
Mahmoud Ghazi-Khansari ◽  
Jalal Pourahmad
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Energy Homeostasis ◽  
Brain Mitochondria ◽  
Depleted Uranium ◽  
Rat Brain Mitochondria ◽  
And Oxidative Stress ◽  
Isolated Rat

Single-walled and multiwalled carbon nanotubes induce oxidative stress in isolated rat brain mitochondria

2019 ◽  
Vol 35 (7) ◽  
pp. 497-506 ◽  
Author(s):  
Saleh Rasras ◽  
Heibatullah Kalantari ◽  
Mohsen Rezaei ◽  
Mohammad Amin Dehghani ◽  
Leila Zeidooni ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Carbon Nanotubes ◽  
Rat Brain ◽  
Multiwalled Carbon Nanotubes ◽  
Mtt Assay ◽  
Brain Mitochondria ◽  
Dependent Manner ◽  
Multiwalled Carbon ◽  
Rat Brain Mitochondria ◽  
Swcnts And Mwcnts

Single-walled carbon nanotubes (SWCNTs) and multiwalled carbon nanotubes (MWCNTs) are broadly applicable across a variety of industrial fields. Despite their usefulness in many different applications, oxidative stress-induced toxicity of SWCNTs and MWCNTs has not been widely investigated. The present study examined the effects of SWCNTs and MWCNTs on rat brain mitochondria using the 3,4 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay and indices of reactive oxygen species (ROS), based on measurements of malondialdehyde (MDA), glutathione (GSH), and mitochondrial membrane potential. Based on the MTT assay, exposure to SWCNTs and MWCNTs decreased mitochondrial survival and viability in a dose-dependent manner. Findings also indicated that MWCNTs and SWCNTs could damage mitochondrial membranes and induce the formation of ROS, as indicated by increased levels of MDA and decreased GSH content. The results of this study suggest that SWCNTs and MWCNTs likely damage brain tissue mitochondria by increasing oxidative stress and possibly activating the apoptosis pathway as well as other pathways of cytotoxicity.

Acyl-CoA: sn-Glycerol-3-Phosphate O-Acyltransferase in Rat Brain Mitochondria and Microsomes

1982 ◽  
Vol 39 (1) ◽  
pp. 286-289 ◽  
Author(s):  
Susan M. Fitzpatrick ◽  
Giovanna Sorresso ◽  
Dipak Haldar
Keyword(s):  
Rat Brain ◽  
Brain Mitochondria ◽  
Rat Brain Mitochondria
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