The role of the brain renin-angiotensin system (RAS) in mild traumatic brain injury (TBI)

2020 ◽  
pp. 107684
Author(s):  
Jason D. Vadhan ◽  
Robert C. Speth
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
The Brain

The potential role of renin-angiotensin system in mild traumatic brain injury

2022 ◽  
Author(s):  
João Luís Vieira Monteiro de Barros ◽  
Maíra Glória Cardoso ◽  
Caroline Amaral Machado ◽  
Érica Leandro Marciano Vieira ◽  
Rodrigo Moreira Faleiro ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Potential Role ◽  
Renin Angiotensin System ◽  
Angiotensin System ◽  
Renin Angiotensin

Renin–angiotensin system as a potential therapeutic target in stroke and retinopathy: experimental and clinical evidence

2016 ◽  
Vol 130 (4) ◽  
pp. 221-238 ◽  
Author(s):  
Abdelrahman Y. Fouda ◽  
Sandeep Artham ◽  
Azza B. El-Remessy ◽  
Susan C. Fagan
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Clinical Studies ◽  
Clinical Evidence ◽  
Renin Angiotensin System ◽  
Potential Therapeutic Target ◽  
Angiotensin System ◽  
Renin Angiotensin

This review examines the published literature on the role of the renin-angiotensin system in neurovascular disorders including stroke, retinopathy, traumatic brain injury and cognitive impairment. The review presents both experimental and clinical studies conducted in the field, and sheds light on the translational gap and clinical underutilization of renin-angiotensin system modulators in neurovascular disorders.

Role of the Brain Renin-angiotensin System in Blood Pressure Regulation

2007 ◽  
Vol 31 (S1) ◽  
pp. 343-346
Author(s):  
M. V. Varoni ◽  
D. Palomba ◽  
M. P. Demontis ◽  
S. Gianorso ◽  
G. L. Pais ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renin Angiotensin System ◽  
Blood Pressure Regulation ◽  
Pressure Regulation ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
The Brain

scholarly journals The Prorenin and (Pro)renin Receptor: New Players in the Brain Renin-Angiotensin System?

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Wencheng Li ◽  
Hua Peng ◽  
Dale M. Seth ◽  
Yumei Feng
Keyword(s):  
Renin Angiotensin System ◽  
Ang Ii ◽  
Future Perspectives ◽  
Vasopressin Release ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Treatment Of Hypertension ◽  
High Level ◽  
The Brain

It is well known that the brain renin-angiotensin (RAS) system plays an essential role in the development of hypertension, mainly through the modulation of autonomic activities and vasopressin release. However, how the brain synthesizes angiotensin (Ang) II has been a debate for decades, largely due to the low renin activity. This paper first describes the expression of the vasoconstrictive arm of RAS components in the brain as well as their physiological and pathophysiological significance. It then focus on the (pro)renin receptor (PRR), a newly discovered component of the RAS which has a high level in the brain. We review the role of prorenin and PRR in peripheral organs and emphasize the involvement of brain PRR in the pathogenesis of hypertension. Some future perspectives in PRR research are heighted with respect to novel therapeutic target for the treatment of hypertension and other cardiovascular diseases.

The Renin Angiotensin System as a potential treatment target for Traumatic Brain Injury

2022 ◽  
Author(s):  
Daniel Hendrik Baron ◽  
Olivia A Skrobot ◽  
Jennifer C Palmer ◽  
Kanchan Sharma ◽  
Patrick Kehoe
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Renin Angiotensin System ◽  
Potential Treatment ◽  
Treatment Target ◽  
Angiotensin System ◽  
Renin Angiotensin
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