scholarly journals A characterized saponin-rich fraction of Momordica charantia shows antidiabetic activity in C57BLK/6 mice fed a high fat diet

2021 ◽  
pp. 100134
Author(s):  
Amy C. Keller ◽  
Kan He ◽  
Anne-Marie Brillantes ◽  
Edward J. Kennelly
Keyword(s):  
High Fat Diet ◽  
Momordica Charantia ◽  
Antidiabetic Activity ◽  
High Fat

Effect of Momordica charantia on Glucagon Secretion in High-fat diet(HFD)/Streptozotocin(STZ)-induced Diabetic Rat

2020 ◽  
Vol 29 (8) ◽  
pp. 837-846
Author(s):  
Seong-Eun Kim ◽  
Sang-Back Kim ◽  
Seul Ki Kim ◽  
Hyun-Kyu Kim ◽  
Byoungjun Park ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Glucagon Secretion ◽  
Momordica Charantia ◽  
Diabetic Rat ◽  
High Fat

scholarly journals PROTECTIVE EFFECT OF ETHANOLIC ROOT EXTRACT OF COMMIPHORA CAUDATA AGAINST DIABETIC-INDUCED RATS IN HIGH-FAT DIET-STREPTOZOTOCIN MODEL

2019 ◽  
pp. 563-566
Author(s):  
ANITHA K ◽  
SABAPATHI MOHANA LAKSHMI ◽  
SATYANARAYANA SV
Keyword(s):  
High Fat Diet ◽  
Histopathological Examination ◽  
Screening Method ◽  
Diabetic Rats ◽  
Antidiabetic Activity ◽  
High Density Lipoproteins ◽  
Phytochemical Analysis ◽  
Root Extract ◽  
High Fat ◽  
Standard Drug

Objective: The present study was to explore the phytochemical analysis and antidiabetic potential of the root of Commiphora caudata in high-fat diet (HFD) streptozotocin-induced diabetic rats. Methods: The ethanolic root extract of C. caudata at a dose of 400 mg/kg and 200 mg/kg was administered to diabetic rats. Glibenclamide (5 mg/kg) was used as standard drug. Results: The data were statistically assessed using one-way ANOVA followed by Dennett’s multiple comparison tests. To unfold the mechanism, we studied all the biochemical parameters glucose, total cholesterol, triglycerides (TG), high-density lipoproteins (HDL), low-density lipoproteins (LDL), and very LDL (VLDL) and histopathological examination of the pancreatic tissue section. The ethanolic extracts of root of C. caudata showed significant reduce of the level of cholesterol, TG, LDL, VLDL, and significant increase in the serum level of HDL at 400 mg/kg rather than 200 mg/kg. Conclusion: Further studies should look into the characterization and isolation of the constituents to know the exact mechanism of hypoglycemic activity. Statistical analyses of this screening method confirm that the proposed method is appropriate and it can be expected to improve basic idea to the researcher who is working in area-like antidiabetic activity.

scholarly journals Momordica charantia improves body weight and glucose tolerance in mice fed high fat diet.

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Fatima Pina ◽  
Angela Brown ◽  
Emily Luebcke ◽  
Penny Perkins‐Veazie ◽  
Stephen Clarke ◽  
...  
Keyword(s):  
Body Weight ◽  
Glucose Tolerance ◽  
High Fat Diet ◽  
Momordica Charantia ◽  
High Fat
Sign in / Sign up

Export Citation Format

Share Document