Relationship of bode index to daily living activities (ADL) limitation and UL grip-strength in chronic obstructive pulmonary disease

We present an assessment of the effectiveness of rehabilitation programs in patients with chronic obstructive pulmonary disease by means of a modified BODE index taking into account the results of four clinical observations using findings of bioimpedanсе analysis.

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Fatigue and multidimensional disease severity in chronic obstructive pulmonary disease

Multidisciplinary Respiratory Medicine ◽

10.4081/mrm.2010.523 ◽

2010 ◽

Vol 5 ◽

Author(s):

Deniz Inal-Ince ◽

Sema Savci ◽

Melda Saglam ◽

Ebru Calik ◽

Hulya Arikan ◽

...

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Pulmonary Disease ◽

Disease Severity ◽

Airflow Obstruction ◽

Muscle Endurance ◽

Chronic Obstructive ◽

Obstructive Pulmonary Disease ◽

Bode Index ◽

Peripheral Muscle ◽

St George's Respiratory Questionnaire

Background and aims: Fatigue is associated with longitudinal ratings of health in patients with chronic obstructive pulmonary disease (COPD). Although the degree of airflow obstruction is often used to grade disease severity in patients with COPD, multidimensional grading systems have recently been developed. The aim of this study was to investigate the relationship between perceived and actual fatigue level and multidimensional disease severity in patients with COPD. Materials and methods: Twenty-two patients with COPD (aged 52-74 years) took part in the study. Multidimensional disease severity was measured using the SAFE and BODE indices. Perceived fatigue was assessed using the Fatigue Severity Scale (FSS) and the Fatigue Impact Scale (FIS). Peripheral muscle endurance was evaluated using the number of sit-ups, squats, and modified push-ups that each patient could do. Results: Thirteen patients (59%) had severe fatigue, and their St George’s Respiratory Questionnaire scores were significantly higher (p < 0.05). The SAFE index score was significantly correlated with the number of sit-ups, number of squats, FSS score and FIS score (p < 0.05). The BODE index was signif- icantly associated with the numbers of sit-ups, squats and modified push-ups, and with the FSS and FIS scores (p < 0.05). Conclusions: Peripheral muscle endurance and fatigue perception in patients with COPD was related to multidimensional disease severity measured with both the SAFE and BODE indices. Improvements in perceived and actual fatigue levels may positively affect multidimensional disease severity and health status in COPD patients. Further research is needed to investigate the effects of fatigue perception and exercise training on patients with different stages of multidimensional COPD severity.

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RELATIONSHIP OF MEAN PLATELET VOLUME WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ITS SEVERITY- AN OBSERVATIONAL STUDY

International Journal of Advanced Research ◽

10.21474/ijar01/13561 ◽

2021 ◽

Vol 9 (10) ◽

pp. 423-428

Author(s):

Kishore Kumar Sharma ◽

Mani Ram Kumhar ◽

Mayank Shrivastav ◽

Harsh Tak

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Body Mass Index ◽

Acute Exacerbation ◽

Mean Platelet Volume ◽

Chronic Obstructive ◽

Platelet Volume ◽

Obstructive Pulmonary Disease ◽

Bode Index ◽

Copd Patients ◽

Relationship Of

Background & Objectives: Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and inflammation. Mean platelet volume (MPV) may be used as a marker of inflammation. We aimed to study the association between MPV and COPD patients during acute attack and relationship of MPV with severity of COPD by FEV1 (%predicted), BODE Index, PaO2, mMRC grade and 6MWD test. Methods: 100 patients with COPD (50 with acute exacerbation and 50 with stable COPD) and 30 healthy controls were enrolled in the study. Mean platelet volume (MPV), spirometry, arterial blood gases, body mass index, renal function tests and BODE index (body mass index, airflow obstruction,dyspnoea and exercise) were assessed. Level of MPV was compared between cases and controls. Results: Of 100 COPD patients, 87(87%) were male and 13(13%)were female.MPV was significantly higher in COPD patients than control and also higher in acute exacerbation group than stable COPD (p=0.001). Interpretation & Conclusions: In the present study,MPV remain in normal range in all COPD patients, but MPV values were significantly higher in COPD cases compared with control.Increased MPV was associated with acute exacerbation and also increasing with severity of COPD.

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