The role of anxiety and depression in the association between early life adversity and metabolism

2020 ◽  
Vol 119 ◽  
pp. 104964
Author(s):  
Eva Unternaehrer ◽  
Maria Meier ◽  
Ulrike Bentele ◽  
Ira Wendland ◽  
Annika Benz ◽  
...  
Keyword(s):  
Early Life ◽  
Anxiety And Depression ◽  
Early Life Adversity

scholarly journals Thyroid Functioning and Fatigue in Women With Functional Somatic Syndromes – Role of Early Life Adversity

2018 ◽  
Vol 9 ◽  
Author(s):  
Susanne Fischer ◽  
Charlotte Markert ◽  
Jana Strahler ◽  
Johanna M. Doerr ◽  
Nadine Skoluda ◽  
...  
Keyword(s):  
Early Life ◽  
Functional Somatic Syndromes ◽  
Early Life Adversity

scholarly journals Effects of early-life adversity on immune function are mediated by prenatal environment: Role of prenatal alcohol exposure

2017 ◽  
Vol 66 ◽  
pp. 210-220 ◽  
Author(s):  
Charlis Raineki ◽  
Tamara S. Bodnar ◽  
Parker J. Holman ◽  
Samantha L. Baglot ◽  
Ni Lan ◽  
...  
Keyword(s):  
Immune Function ◽  
Early Life ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Early Life Adversity ◽  
Prenatal Environment ◽  
Prenatal Alcohol

scholarly journals Early-life adversity and adolescent depression: mechanisms involving the ventral striatum

CNS Spectrums ◽  
2014 ◽  
Vol 20 (4) ◽  
pp. 337-345 ◽  
Author(s):  
Bonnie Goff ◽  
Nim Tottenham
Keyword(s):  
Neural Development ◽  
Early Life ◽  
Adolescent Depression ◽  
Ventral Striatum ◽  
Reward Processing ◽  
Limbic Structure ◽  
Early Life Adversity ◽  
Reward Circuitry ◽  
Established Risk Factor

Early-life adversity is a well-established risk factor for the development of depression later in life. Here we discuss the relationship between early-life adversity and depression, focusing specifically on effects of early-life caregiver deprivation on alterations in the neural and behavioral substrates of reward-processing. We also examine vulnerability to depression within the context of sensitive periods of neural development and the timing of adverse exposure. We further review the development of the ventral striatum, a limbic structure implicated in reward processing, and its role in depressive outcomes following early-life adversity. Finally, we suggest a potential neurobiological mechanism linking early-life adversity and altered ventral striatal development. Together these findings may help provide further insight into the role of reward circuitry dysfunction in psychopathological outcomes in both clinical and developmental populations.

Addiction, inequality and recovery

2017 ◽  
Author(s):  
Jenny Svanberg
Keyword(s):  
Substance Use ◽  
Health Outcomes ◽  
Health Inequalities ◽  
Early Life ◽  
Early Life Adversity ◽  
Health Equality ◽  
Societal Inequality ◽  
Rich Countries ◽  
The Impact

This chapter examines the impact of health inequalities on addiction and how the recommendations of the Marmot Review could influence recovery from addiction. The Marmot Review was tasked with devising strategies to reduce health inequalities in England, and rightly recognised that health equality requires a debate about what kind of society we want to live in. When considering societies as a whole, there is a clearer relationship between poor health outcomes and societal inequality; rich countries with a steep social gradient do worse than poorer, but more equal, countries. The chapter first provides an overview of factors that cause substance use and addiction before discussing the role of early life adversity in addiction and the link between inequality and addiction. More specifically, it explains how unequal societies lead to addiction and goes on to consider how society can support recovery from addiction.

Formalizing the Relationship Between Early Life Adversity and Addiction Vulnerability: The Role of Memory Sampling

2021 ◽  
Vol 89 (9) ◽  
pp. S189
Author(s):  
Nora Harhen ◽  
Tallie Z. Baram ◽  
Michael A. Yassa ◽  
Aaron M. Bornstein
Keyword(s):  
Early Life ◽  
Early Life Adversity ◽  
The Relationship

scholarly journals Early Life Adversity and Children’s Competence Development: Evidence from the Mannheim Study of Children at Risk

2013 ◽  
Vol 233 (4) ◽  
pp. 467-485 ◽  
Author(s):  
Dorothea Blomeyer ◽  
Manfred Laucht ◽  
Katja Coneus ◽  
Friedhelm Pfeiffer
Keyword(s):  
Home Environment ◽  
Early Life ◽  
School Achievement ◽  
Preschool Age ◽  
School Age ◽  
Early Life Adversity ◽  
Psychosocial Risks ◽  
Trade Offs ◽  
Epidemiological Cohort

Summary This paper investigates the role of early life adversity and home resources in terms of competence formation and school achievement based on data from an epidemiological cohort study following 364 children from birth to adolescence. Results indicate that organic and psychosocial risks present in early life as well as the socio-emotional home environment are significant predictors for the formation of competencies. Competencies acquired at preschool age predict achievement at school age. A counterfactual analysis is performed to assess trade-offs in the timing of interventions in the early life cycle.

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