Regarding Davis et al.: Assessment of 18F PET signals for automatic target volume definition in radiotherapy treatment planning

2007 ◽  
Vol 83 (1) ◽  
pp. 102-103 ◽  
Author(s):  
Aswin L. Hoffmann ◽  
Jorn A. van Dalen ◽  
John Lee ◽  
Vincent Grégoire ◽  
Wim J.G. Oyen ◽  
...  
2017 ◽  
Vol 17 (3) ◽  
pp. 337-346
Author(s):  
Auwal Abubakar ◽  
Adamu D. Bojude ◽  
Aminu U. Usman ◽  
Idris Garba ◽  
Abasiama D. Obotiba ◽  
...  

AbstractPurposeThe aim of this study is to establish clinical evidence regarding the use of magnetic resonance imaging (MRI) in target volume definition for radiotherapy treatment planning of brain tumours.MethodsPrimary studies were systematically retrieved from six electronic databases and other sources. Studies included were only those that quantitatively compared computed tomography (CT) and MRI in target volume definition for radiotherapy of brain tumours. Study characteristics and quality were assessed and the data were extracted from eligible studies. Effect estimates for each study was computed as mean percentage difference based on individual patient data where available. The included studies were then combined in meta-analysis using Review Manager (RevMan) software version 5.0.ResultFive studies with a total number of 72 patients were included in this review. The quality of the studies was rated strong. The percentages mean differences of the studies were 7·47, 11·36, 30·70, 41·69 and −24·6% using CT as the baseline. The result of statistical analysis showed small-to-moderate heterogeneity; τ2=36·8; χ2=6·23; df=4 (p=0·18); I2=36%. The overall effect estimate was −1·85 [95% confidence interval (CI); −7·24, 10·94], Z=0·40 (p=0·069>0·5).ConclusionBrain tumour volumes measured using MRI-based method for radiotherapy treatment planning were larger compared with CT defined volumes but the difference lacks statistical significance.


2006 ◽  
Vol 80 (1) ◽  
pp. 43-50 ◽  
Author(s):  
J. Bernard Davis ◽  
Beatrice Reiner ◽  
Marius Huser ◽  
Cyrill Burger ◽  
Gábor Székely ◽  
...  

2012 ◽  
Vol 103 ◽  
pp. S305
Author(s):  
E. Serup-Hansen ◽  
H. Westergreen Hendel ◽  
H. Hjorth Johannesen ◽  
W. Ottosson ◽  
B. Kristensen ◽  
...  

2011 ◽  
Vol 84 (1006) ◽  
pp. 919-929 ◽  
Author(s):  
G G Hanna ◽  
J R Van Sörnsen De Koste ◽  
K J Carson ◽  
J M O'Sullivan ◽  
A R Hounsell ◽  
...  

2016 ◽  
Vol 32 ◽  
pp. 64
Author(s):  
A. Stefano ◽  
S. Vitabile ◽  
G. Russo ◽  
D. D'Urso ◽  
M. Ippolito ◽  
...  

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
P. Franzone ◽  
A. Muni ◽  
E. Cazzulo ◽  
L. Berretta ◽  
G. Pozzi ◽  
...  

CT/PET is useful in early diagnosis, staging, follow-up and in radiotherapy treatment planning especially for tumors located in motion involved anatomic areas (chest and abdomen). We analysed the treatment planning for radiotherapy of two pulmonary cancer patients. A comparison was performed between GTV (Gross Tumor Volume) and PTV (Planning Target Volume) identified with CT images alone and GTV and PTV evaluated with CT/PET images. CT/PET imaging was demonstrated to significantly modify the target volume if compared with CT imaging: volumes were reduced by 32-49%.


2013 ◽  
Vol 70 (8) ◽  
pp. 735-739 ◽  
Author(s):  
Igor Djan ◽  
Borislava Petrovic ◽  
Marko Erak ◽  
Ivan Nikolic ◽  
Silvija Lucic

Background/Aim. Development of imaging techniques, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), made great impact on radiotherapy treatment planning by improving the localization of target volumes. Improved localization allows better local control of tumor volumes, but also minimizes geographical misses. Mutual information is obtained by registration and fusion of images achieved manually or automatically. The aim of this study was to validate the CT-MRI image fusion method and compare delineation obtained by CT versus CT-MRI image fusion. Methods. The image fusion software (XIO CMS 4.50.0) was applied to delineate 16 patients. The patients were scanned on CT and MRI in the treatment position within an immobilization device before the initial treatment. The gross tumor volume (GTV) and clinical target volume (CTV) were delineated on CT alone and on CT+MRI images consecutively and image fusion was obtained. Results. Image fusion showed that CTV delineated on a CT image study set is mainly inadequate for treatment planning, in comparison with CTV delineated on CT-MRI fused image study set. Fusion of different modalities enables the most accurate target volume delineation. Conclusion. This study shows that registration and image fusion allows precise target localization in terms of GTV and CTV and local disease control.


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