scholarly journals Update on the efficacy of statins in primary and secondary prevention of atrial fibrillation

Author(s):  
Alireza Oraii ◽  
Farzad Masoudkabir
Author(s):  
Kristaps Jurjāns ◽  
Santa Sabeļnikova ◽  
Evija Miglāne ◽  
Baiba Luriņa ◽  
Oskars Kalējs ◽  
...  

Abstract Atrial fibrillation is one of major risk factors of cerebral infarction. The use of oral anticoagulants is the only evidence-based method of reducing the risk of cardioembolic accidents. The guidelines of oral anticoagulant admission and usage have been available since 2012. The results of this study show that of 550 stroke patients that were admitted to Pauls Stradiņš Clinical University Hospital, Rīga, Latvia, from 1 January 2014 until 1 July 2014, atrial fibrillation was diagnosed in 247 (45%) cases, and of these patients, only 8.5% used oral anticoagulants before the onset of stroke. Six months after discharge of 111 (44.9%) stroke survivors, five (4.5%) used no secondary prevention medication, 27 (24.3%) used antiplatelet agents, 54 (48.6%) warfarin, and 25 (22.5%) used target specific oral anticoagulants (TSOACs). The mortality rate was significantly higher in the patient group that used no secondary prevention medication or antiplatelet agents compared to the patient group that used oral anticoagulants. The use of oral anticoagulants for primary stroke prevention in Latvia is insufficient. The mortality of cardioembolic stroke in 180 days is very high - 40.4%. Secondary prevention is essential to prevent recurrent cardioembolic accidents.


2019 ◽  
Vol 34 (3) ◽  
pp. 13-20
Author(s):  
M. A. Kirgizova ◽  
R. E. Batalov ◽  
B. A. Tatarsky ◽  
S. V. Popov

The present literature review is devoted to the analysis of the features of the pathogenesis of atrial fibrillation in patients with arterial hypertension and to the optimal treatment tactics in this cohort of patients. In particular, pathological mechanisms (hemodynamic, structural, and electrophysiological) of the development of atrial fibrillation in arterial hypertension are reviewed. The article highlights the problems of primary and secondary prevention of atrial fibrillation using antihypertensive therapy as well as the aspects of the prevention of thromboembolic complications in patients with atrial fibrillation and arterial hypertension.


2021 ◽  
Vol 40 (7) ◽  
pp. 509-518
Author(s):  
Alireza Oraii ◽  
Ali Vasheghani-Farahani ◽  
Saeed Oraii ◽  
Pegah Roayaei ◽  
Pargol Balali ◽  
...  

2020 ◽  
Author(s):  
Nebojša Mujović ◽  
Milan Marinković ◽  
Miroslav Mihajlović ◽  
Nataša Mujović ◽  
Tatjana S. Potpara

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