Comparison of the anti-inflammatory effect of aripiprazole and risperidone in 75 drug-naïve first episode psychosis individuals: A 3 months randomized study

2018 ◽  
Vol 202 ◽  
pp. 226-233 ◽  
Author(s):  
María Juncal-Ruiz ◽  
Laura Riesco-Dávila ◽  
Víctor Ortiz-García de la Foz ◽  
Obdulia Martínez-Garcia ◽  
Mariluz Ramírez-Bonilla ◽  
...  
Keyword(s):  
Randomized Study ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Drug Naïve ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28

2017 ◽  
Vol 22 (6) ◽  
pp. 850-856 ◽  
Author(s):  
K Collste ◽  
◽  
P Plavén-Sigray ◽  
H Fatouros-Bergman ◽  
P Victorsson ◽  
...  
Keyword(s):  
Glial Cell ◽  
First Episode Psychosis ◽  
First Episode ◽  
Cell Marker ◽  
Episode Psychosis ◽  
Drug Naïve

Pituitary volume and early treatment response in drug-naïve first-episode psychosis patients

2009 ◽  
Vol 113 (1) ◽  
pp. 65-71 ◽  
Author(s):  
B. Garner ◽  
G.E. Berger ◽  
J.P. Nicolo ◽  
A. Mackinnon ◽  
S.J. Wood ◽  
...  
Keyword(s):  
Treatment Response ◽  
Early Treatment ◽  
First Episode Psychosis ◽  
First Episode ◽  
Early Treatment Response ◽  
Episode Psychosis ◽  
Drug Naïve

Plasma prolactin levels are associated with the severity of illness in drug-naive first-episode psychosis female patients

2018 ◽  
Vol 22 (3) ◽  
pp. 367-373 ◽  
Author(s):  
Manuel Delgado-Alvarado ◽  
Diana Tordesillas-Gutierrez ◽  
Rosa Ayesa-Arriola ◽  
Manuel Canal ◽  
Victor Ortiz-García de la Foz ◽  
...  
Keyword(s):  
Severity Of Illness ◽  
First Episode Psychosis ◽  
First Episode ◽  
Plasma Prolactin ◽  
Female Patients ◽  
Episode Psychosis ◽  
Drug Naïve

Using structural equations to test for a direct effect of some antipsychotics on triglyceride levels in drug-naïve first-episode psychosis patients

2011 ◽  
Vol 131 (1-3) ◽  
pp. 82-89 ◽  
Author(s):  
Francisco J. Diaz ◽  
Rocio Perez-Iglesias ◽  
Ignacio Mata ◽  
Obdulia Martínez-Garcia ◽  
José L. Vázquez-Barquero ◽  
...  
Keyword(s):  
Direct Effect ◽  
First Episode Psychosis ◽  
Structural Equations ◽  
First Episode ◽  
Episode Psychosis ◽  
Drug Naïve

scholarly journals Aripiprazole for Drug-Naive or Antipsychotic-Short-Exposure Subjects With Ultra-High Risk State and First-Episode Psychosis

2013 ◽  
Vol 33 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Chen-Chung Liu ◽  
Yi-Ling Chien ◽  
Ming H. Hsieh ◽  
Tzung-Jeng Hwang ◽  
Hai-Gwo Hwu ◽  
...  
Keyword(s):  
High Risk ◽  
First Episode Psychosis ◽  
Short Exposure ◽  
First Episode ◽  
Episode Psychosis ◽  
Ultra High Risk ◽  
Drug Naïve

scholarly journals Expression and Functionality Study of 9 Toll-Like Receptors in 33 Drug-Naïve Non-Affective First Episode Psychosis Individuals: A 3-Month Study

2020 ◽  
Vol 21 (17) ◽  
pp. 6106
Author(s):  
Maria Juncal-Ruiz ◽  
Laura Riesco-Davila ◽  
Javier Vazquez-Bourgon ◽  
Victor Ortiz-Garcia de la Foz ◽  
Jacqueline Mayoral-Van Son ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Mononuclear Cells ◽  
First Episode Psychosis ◽  
First Episode ◽  
Antipsychotic Treatment ◽  
Toll Like Receptors ◽  
Peripheral Blood Mononuclear ◽  
Episode Psychosis ◽  
Tnf Α ◽  
Drug Naïve

Toll-like receptors (TLRs) are a pivotal component of the innate immune system that seem to have a role in the pathogenesis of psychosis. The purpose of this work was to compare the expression and functionality of 9 TLRs in three peripheral blood mononuclear cells (PBMCs) (monocytes, B cells, and T cells) between 33 drug-naïve first-episode psychosis (FEP) individuals and 26 healthy volunteers, at baseline and after 3-month of antipsychotic treatment. The expression of TLRs 1–9 were assessed by flow cytometry. For the assessment of the TLR functionality, cells collected in sodium heparin tubes were polyclonally stimulated for 18 h, with different agonists for human TLR1–9. The results of our study highlight the role that TLR5 and TLR8 might play in the pathophysiology of psychosis. We found a lower expression of these receptors in FEP individuals, regarding healthy volunteers at baseline and after 3-month of treatment on the three PBMCs subsets. Most TLRs showed a lower functionality (especially reduced intracellular levels of TNF-α) in patients than in healthy volunteers. These results, together with previous evidence, suggest that individuals with psychosis might show a pattern of TLR expression that differs from that of healthy volunteers, which could vary according to the intensity of immune/inflammatory response.

Prospective memory performance in patients with drug-naïve, first-episode psychosis

2013 ◽  
Vol 143 (2-3) ◽  
pp. 285-290 ◽  
Author(s):  
Kaiming Zhuo ◽  
Yun Lu ◽  
Zhiliang Yang ◽  
Xiaoduo Fan ◽  
Zhenhua Song ◽  
...  
Keyword(s):  
Prospective Memory ◽  
Memory Performance ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Drug Naïve ◽  
Prospective Memory Performance
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