Ambulatory Assessment of Socio-Affective and Cognitive Aging: Zooming Into Daily Processes

Ambulatory assessment methods offer new possibilities to study cognitive, emotional, and social processes in the setting in which they naturally occur, namely in the daily life of individuals and couples. This allows to zoom into processes with great relevance for healthy aging and well-being over the lifespan. Research on daily psychological processes opens the door for investigating the interplay with contextual (daily stress, social resources) and stable factors (relationship quality status, accumulated discrimination) that are known to shape these dynamic processes. This symposium will present and discuss innovative contributions investigating daily emotional and cognitive functioning and their interplay with social and individual characteristics over the adult lifespan. The first study by Haas and colleagues will present experience sampling data on daily prospective memory performance in couples. Haas et al. will offer a dyadic perspective on cognitive functioning by examining how prospective memory performance is co-regulated in the daily lives of younger and older couples. Meier et al. will present another study from the same couples project; here the focus is on age differences in couples’ “we-ness” and its relationship with daily positive emotional experiences and how they are shared with the partner. The series of talks will be completed by Zavala et al. who examined associations between stress and emotional health in daily life and its interplay with prior discrimination experiences of an age-diverse sample of BIPOC adults. After these individual contributions, Christina Roecke will discuss the presented studies and provide her reflections on the results and their implications.

Placebos Affect Retrospective and Prospective Memory Performance by Increasing Monitoring

<p>Decreasing physical pain, increasing emotional wellbeing, and improving physical health are just some of the ways placebos have affected people's physiological and psychological health (Crum & Langer, 2007; Kirsch & Sapirstein, 1999; Montgomery & Kirsch, 1997). Recently, Clifasefi, Garry, Harper, Sharman, and Sutherland (2007) demonstrated that a memory placebo called R273 could even reduce people's susceptibility to misleading information. Yet how could a substance with no physiologically active properties affect memory performance? That is the overarching question of this thesis. In order to monitor the sources of information about the past, and in order to remember future tasks and actions, people can either use an effortful monitoring process, or they can rely on their usual, automatic and effortless memory processes. Typically, the more monitoring that people use, the better their memory performance (Johnson, Hashtroudi, & Lindsay, 1993; Einstein et al., 2005). In this thesis, over three experiments, I examined how a placebo might affect the way people monitor information, thus improving aspects of retrospective and prospective memory. Experiment 1 examined whether R273 reduces people's susceptibility to the misinformation effect by leading them to switch from their habitual, automatic, and easy source monitoring to more deliberate and effortful source monitoring. To examine this question I used Clifasefi et al.'s (2007) sham drug procedure and then ran subjects through a three-stage misinformation experiment (Loftus, Miller, & Burns, 1978). The results of Experiments 1 suggest that R273 did not affect effortful monitoring during the post event information (PEI), but did affect effortful monitoring during the memory test. Experiment 2 aimed to find further evidence that R273 affects people's monitoring during the memory test. To address this question, all subjects were told that they had received an inactive drug before they took part in the first two stages of the misinformation effect paradigm. Immediately before taking the memory test, however, I falsely told some people that they had actually received R273. The primary finding of Experiment 2 added support to the idea that R273 affects subjects source monitoring during the memory test: Told Drug subjects were less misled than their Told Inactive counterparts. Finally, Experiment 3 further examined whether R273 leads people to use effortful monitoring, but did so using a prospective memory task, whose underlying memory processes align closely with those of source monitoring. The results showed that Told Drug subjects were slower to perform an ongoing and concurrent task, yet had better prospective memory performance than Told Inactive subjects. These results suggested that R273 lead Told Drug subjects' to use more effortful monitoring. In conclusion, the results suggest that the sham cognitive enhancing placebo R273 improves people's ability to resist misleading suggestion, and perform prospective memory tasks because it leads them to use more effortful monitoring.</p>

Placebos Affect Retrospective and Prospective Memory Performance by Increasing Monitoring

<p>Decreasing physical pain, increasing emotional wellbeing, and improving physical health are just some of the ways placebos have affected people's physiological and psychological health (Crum & Langer, 2007; Kirsch & Sapirstein, 1999; Montgomery & Kirsch, 1997). Recently, Clifasefi, Garry, Harper, Sharman, and Sutherland (2007) demonstrated that a memory placebo called R273 could even reduce people's susceptibility to misleading information. Yet how could a substance with no physiologically active properties affect memory performance? That is the overarching question of this thesis. In order to monitor the sources of information about the past, and in order to remember future tasks and actions, people can either use an effortful monitoring process, or they can rely on their usual, automatic and effortless memory processes. Typically, the more monitoring that people use, the better their memory performance (Johnson, Hashtroudi, & Lindsay, 1993; Einstein et al., 2005). In this thesis, over three experiments, I examined how a placebo might affect the way people monitor information, thus improving aspects of retrospective and prospective memory. Experiment 1 examined whether R273 reduces people's susceptibility to the misinformation effect by leading them to switch from their habitual, automatic, and easy source monitoring to more deliberate and effortful source monitoring. To examine this question I used Clifasefi et al.'s (2007) sham drug procedure and then ran subjects through a three-stage misinformation experiment (Loftus, Miller, & Burns, 1978). The results of Experiments 1 suggest that R273 did not affect effortful monitoring during the post event information (PEI), but did affect effortful monitoring during the memory test. Experiment 2 aimed to find further evidence that R273 affects people's monitoring during the memory test. To address this question, all subjects were told that they had received an inactive drug before they took part in the first two stages of the misinformation effect paradigm. Immediately before taking the memory test, however, I falsely told some people that they had actually received R273. The primary finding of Experiment 2 added support to the idea that R273 affects subjects source monitoring during the memory test: Told Drug subjects were less misled than their Told Inactive counterparts. Finally, Experiment 3 further examined whether R273 leads people to use effortful monitoring, but did so using a prospective memory task, whose underlying memory processes align closely with those of source monitoring. The results showed that Told Drug subjects were slower to perform an ongoing and concurrent task, yet had better prospective memory performance than Told Inactive subjects. These results suggested that R273 lead Told Drug subjects' to use more effortful monitoring. In conclusion, the results suggest that the sham cognitive enhancing placebo R273 improves people's ability to resist misleading suggestion, and perform prospective memory tasks because it leads them to use more effortful monitoring.</p>

Sleep, Prospective Memory, and Immune Status among People Living with HIV

Background: Persons living with HIV (PLWH) frequently report sleep complaints, but objective measurements are still lacking regarding sleep continuity, total sleep time per 24 h, and the links with both prospective memory performance and HIV infection parameters. Methods: PLWH (n = 96) and control (n = 96) groups (balanced for gender and age) were monitored by 24h-actigraphy for at least seven consecutive days. The prospective memory performance was assessed through a naturalistic, activity-based task performed twice a day on the actigraph. Results: PLWH had greater sleep latency and worse sleep continuity (higher fragmentation index) for night-time sleep and longest daytime nap (mean duration of the longest nap). Comparable results were reported for the prospective memory task; better performance scores were associated with several sleep parameters in controls but not in PLWH. Finally, within the PLWH group, being a long sleeper per 24 h (total sleep time > 8 h including more and long daytime naps) was associated with a greater severity of the disease (lower CD4 nadir and more frequent history of AIDS-defining events). Conclusions: These findings indicate that PLWH have more fragmented sleep and that the severity of HIV infection is associated with increased sleep duration.