scholarly journals Temporal variation in the incidence of treated psychotic disorders in young people

2021 ◽  
Vol 231 ◽  
pp. 221-226
Author(s):  
Baptiste Pignon ◽  
Scott Eaton ◽  
Franck Schürhoff ◽  
Andrei Szöke ◽  
Patrick McGorry ◽  
...  
Keyword(s):  
Young People ◽  
Temporal Variation ◽  
Psychotic Disorders

scholarly journals Questioning the ‘neuroprotective’ hypothesis: does drug treatment prevent brain damage in early psychosis or schizophrenia?

2011 ◽  
Vol 198 (2) ◽  
pp. 85-87 ◽  
Author(s):  
Joanna Moncrieff
Keyword(s):  
Young People ◽  
Drug Treatment ◽  
Brain Damage ◽  
Early Treatment ◽  
Psychotic Disorders ◽  
Early Psychosis ◽  
Progressive Neurodegeneration ◽  
New Generation

SummaryThe idea that psychotic disorders are characterised by progressive neurodegeneration that can be reversed by drug treatment is used to justify early treatment of increasing numbers of mostly young people. I argue that there is little evidence to support the view that old- or new-generation antipsychotics are ‘neuroprotective’, and some evidence that the drugs themselves may be responsible for the decline in brain matter observed in some studies.

PACE: a specialised service for young people at risk of psychotic disorders

2007 ◽  
Vol 187 (S7) ◽  
Author(s):  
Alison R Yung ◽  
Patrick D McGorry ◽  
Shona M Francey ◽  
Barnaby Nelson ◽  
Kathryn Baker ◽  
...  
Keyword(s):  
At Risk ◽  
Young People ◽  
Psychotic Disorders

The First Episode of Psychosis

2021 ◽  
Author(s):  
Beth Broussard ◽  
Michael T. Compton
Keyword(s):  
Young People ◽  
Psychotic Disorders ◽  
Healthy Lifestyle ◽  
Early Adulthood ◽  
Warning Signs ◽  
First Episode ◽  
Care Providers ◽  
Early Intervention Services ◽  
Lifestyle Choices ◽  
Healthy Lifestyle Choices

Now in its second edition, The First Episode of Psychosis is the ideal book for young people and their families experiencing the frightening and confusing initial episode of psychosis, which often occurs during late adolescence or early adulthood. The updated edition includes information on specialized early intervention services, going back to school and work, and the latest treatments and medicines. The book covers a range of topics essential for young people and families facing the challenges of psychosis. Topics covered include early warning signs, symptoms, types of primary psychotic disorders such as schizophrenia and schizophreniform disorder, evaluation, treatment, and healthy lifestyle choices. Worksheets helps readers to track and better understand their own experiences, and to openly communicate with care providers. An extensive glossary clarifies the dizzying array of terms used by medical professionals. Optimistic, practical, and recovery-oriented, The First Episode of Psychosis will help young people and their families take an active, informed role in their care as they take steps towards achieving their goals.

Prevalence of subthreshold positive symptoms in young people without psychotic disorders presenting to a youth mental health service

2020 ◽  
Vol 215 ◽  
pp. 446-448 ◽  
Author(s):  
Natalie Seiler ◽  
James Maguire ◽  
Tony Nguyen ◽  
Holly Sizer ◽  
Patrick McGorry ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Health Service ◽  
Young People ◽  
Health Service ◽  
Psychotic Disorders ◽  
Youth Mental Health ◽  
Positive Symptoms

Cyber-victimisation and mental health in young people: a co-twin control study

2020 ◽  
pp. 1-11
Author(s):  
Jessie R. Baldwin ◽  
Ziada Ayorech ◽  
Fruhling V. Rijsdijk ◽  
Tabea Schoeler ◽  
Jean-Baptiste Pingault
Keyword(s):  
Mental Health ◽  
Young People ◽  
Psychotic Disorders ◽  
Mental Health Problems ◽  
Monozygotic Twins ◽  
Health Problems ◽  
Individual Level ◽  
Face To Face ◽  
Direct Association ◽  
The Impact

Abstract Background The rise of social media use in young people has sparked concern about the impact of cyber-victimisation on mental health. Although cyber-victimisation is associated with mental health problems, it is not known whether such associations reflect genetic and environmental confounding. Methods We used the co-twin control design to test the direct association between cyber-victimisation and multiple domains of mental health in young people. Participants were 7708 twins drawn from the Twins Early Development Study, a UK-based population cohort followed from birth to age 22. Results Monozygotic twins exposed to greater levels of cyber-victimisation had more symptoms of internalising, externalising and psychotic disorders than their less victimised co-twins at age 22, even after accounting for face-to-face peer victimisation and prior mental health. However, effect sizes from the most stringent monozygotic co-twin control analyses were decreased by two thirds from associations at the individual level [pooled β across all mental health problems = 0.06 (95% CI 0.03–0.10) v. 0.17 (95% CI 0.15–0.19) in individual-level analyses]. Conclusions Cyber-victimisation has a small direct association with multiple mental health problems in young people. However, a large part of the association between cyber-victimisation and mental health is due to pre-existing genetic and environmental vulnerabilities and co-occurring face-to-face victimisation. Therefore, preventative interventions should target cyber-victimisation in conjunction with pre-existing mental health vulnerabilities and other forms of victimisation.

Clinical Profiles, Scope and General Findings of the Western Sydney First Episode Psychosis Project

2005 ◽  
Vol 39 (1-2) ◽  
pp. 36-43 ◽  
Author(s):  
Anthony Harris ◽  
John Brennan ◽  
Josephine Anderson ◽  
Anne Taylor ◽  
Mark Sanbrook ◽  
...  
Keyword(s):  
Mental Health ◽  
Young People ◽  
Health Services ◽  
Social Functioning ◽  
Mood Disorders ◽  
Negative Symptoms ◽  
Psychotic Disorders ◽  
The Other ◽  
First Episode ◽  
Schizophrenia Group

Objective: To examine the clinical profile, treatment and social functioning of a communitybased sample of young people presenting with their first episode of psychosis. Methods: Over a 2-year period, young people with their first episode of psychosis referred to early intervention services in two area mental health services in western Sydney were assessed with a battery of clinical, neuropsychological, psychophysiological and neuroanatomical measures. This paper reports the clinical results of the baseline section of the study. Results: Of the 224 referrals to the project, 94 subjects meet inclusion criteria and agreed to take part. Subjects were divided into three diagnostic groups – ‘Schizophrenia’, ‘Mood Disorders’ and ‘Mixed Psychosis’, the latter principally comprised of substance induced psychotic disorders. Subjects from the ‘Schizophrenia’ group differed significantly from the other two groups in that they had higher levels of negative symptoms and general psychopathology, and were less likely to be employed or engaged in study. They had poorer overall social functioning. Subjects with ‘Mixed Psychosis’ were similar to those from the ‘Schizophrenia’ group in that they were older and male, but they did not have the same burden of negative symptoms as the ‘Schizophrenia’ group. The ‘Mood Disorders’ group was younger, female and had overall a higher level of psychosocial functioning than the other two groups. Subjects from the ‘Mood Disorders’ group were more likely to be managed with mood stabilisers and multiple drug therapies. The use of atypical antipsychotic medication was almost universal. Conclusions: Even shortly after the time of presentation to mental health services young people with a schizophrenia spectrum diagnosis have a heavier burden of symptoms and are significantly more impaired by them than young people with other psychotic illnesses. This and their symptom profile differentiated them from young people with other psychotic disorders.

Neuropsychological Clustering Highlights Cognitive Differences In Young People Presenting With Depressive Symptoms

2011 ◽  
Vol 17 (2) ◽  
pp. 267-276 ◽  
Author(s):  
Daniel F. Hermens ◽  
M. Antoinette Redoblado Hodge ◽  
Sharon L. Naismith ◽  
Manreena Kaur ◽  
Elizabeth Scott ◽  
...  
Keyword(s):  
Young People ◽  
Help Seeking ◽  
Psychotic Disorders ◽  
Depressive Symptomatology ◽  
Function Analysis ◽  
Hierarchical Cluster ◽  
Attention And Memory ◽  
Original Solution ◽  
Early Stages ◽  
Impaired Attention

AbstractEarly stages of affective or psychotic disorders may be accompanied by neuropsychological changes that help to predict risk of developing more severe disorders. A comprehensive set of neuropsychological measures was collected in 109 help-seeking young people (16 to 30 years; 54 females), recently diagnosed with an affective or psychotic disorder and presenting with current depression. Hierarchical cluster analysis determined three clusters: one deemed to have a “poor memory” profile (n = 40); another with a “poor mental flexibility” profile (n = 38) and a third with widespread difficulties plus “impaired attention and memory” (n = 31). In general, the three clusters were comparable in demographic, functional and clinical factors suggesting some unique role for neurocognitive impairments. A discriminant function analysis confirmed that the clusters were best characterized by performance in “attentional” versus “learning/memory” measures. Furthermore, profiles of independent neuropsychological variables validated the original solution for two of the clusters, distinguishing all cluster-groups on an attentional measure. The findings of this study suggest that despite presenting with very similar levels of current depressive symptomatology, young help-seeking individuals in the early stages of illness have underlying neuropsychological heterogeneity. Distinct neuropsychological profiling may help to predict later psychiatric outcomes and enhance individually-tailored early intervention strategies. (JINS, 2011, 17, 267–276)

Early intervention program for psychosis: Experience and results in a mental health center

2011 ◽  
Vol 26 (S2) ◽  
pp. 1163-1163
Author(s):  
M.C. Campos Mangas ◽  
M.A. Ruiz Feliu
Keyword(s):  
Early Intervention ◽  
Young People ◽  
Psychotic Disorder ◽  
Intervention Program ◽  
Psychotic Disorders ◽  
Mental Health Center ◽  
Community Treatment ◽  
Initial Assessment ◽  
Psychotic Symptoms ◽  
List Type

IntroductionThis program aims to assist young people aged 16 to 35 years at risk for or who have a severe mental disorder, a psychosis both affected and unaffected, according to the principles of early intervention and assertive community treatment.ObjectivesAssisting young people with psychosis in order to achieve symptomatic and functional recovery, return to provide standardized environment and prevent deterioration.MethodsInitial assessment is made and individualized plan of work.Inclusion criteria1.Diagnosis: substance-induced psychotic disorder, schizophrenia and other psychotic disorders, bipolar disorder and mood disorders with psychotic symptoms2.age: 16–35 years3.Informed consentEvaluation ToolsPANSS, SCIP, CDS, CGI-S, PAS, CAN, EU, SFS, GAF, WHOQUOL-BREF, IEQ-EU, UKU, HoNOS, CGI-IP, CGI-ICResultsThe sample consisted of 22 patients. 45.5% men and 54.5% women. Mean age 24 (SD = 4.74). Diagnosis: schizophrenia 54.5%, 27.3% acute psychotic disorder, 4.5% and 13.6% schizoaffective disorder manic episode with psychotic symptoms. Clinical stage at the beginning of the program: 45.5% stage 2, 4.5% stage 3a; 22.7% stage 3b, 3c stage 22.7% and 4.5% stage 4.ConclusionsIt is necessary to implement such programs to establish the treatment as soon as possible to the onset of the disease and improve prognosis.

scholarly journals Early intervention in youth mental health: progress and future directions

2018 ◽  
Vol 21 (4) ◽  
pp. 182-184 ◽  
Author(s):  
Patrick D McGorry ◽  
Cristina Mei
Keyword(s):  
Mental Health ◽  
Health Care ◽  
Early Intervention ◽  
Young People ◽  
Mental Health Care ◽  
Psychotic Disorders ◽  
Young Patients ◽  
Youth Mental Health ◽  
Mental Illnesses ◽  
The Past

Early intervention is a fundamental principle in health care and the past two decades have seen it belatedly introduced into the field of mental health. This began in psychotic disorders, arguably the least promising place to start. The steady accumulation of scientific evidence for early intervention has eventually overwhelmed the sceptics, transformed thinking in psychotic disorders and created an international wave of service reform. This paradigm shift has paved the way to a more substantial one: early intervention across the full diagnostic spectrum. 75% of mental illnesses emerge before the age of 25 years, and young people bear the major burden for those disorders that threaten the many decades of productive adult life. The paradox is that young people aged between 12 and 25 years have had by far the worst levels of access to mental health care across the whole lifespan. Health services are poorly designed, grossly under-resourced and typically unfriendly to, and untrusted by, young people. Furthermore, until recently there has been a quite striking lack of interest in this transitional age group from clinicians and researchers alike, who had unthinkingly accepted the paediatric–adult split of mainstream medicine without questioning its utility and validity for our field and our young patients. Over the past decade, however, a major shift in momentum has occurred to take early intervention in youth mental health more seriously. Here we discuss the recent advances and evidence supporting an innovative integrated model of youth mental health care and look to the future.

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