Differential proteomic expression of human placenta and fetal development following e-waste lead and cadmium exposure in utero

2016 ◽  
Vol 550 ◽  
pp. 1163-1170 ◽  
Author(s):  
Long Xu ◽  
Jingjing Ge ◽  
Xia Huo ◽  
Yuling Zhang ◽  
Andy T.Y. Lau ◽  
...  
Keyword(s):  
Human Placenta ◽  
Fetal Development ◽  
In Utero ◽  
Cadmium Exposure ◽  
Lead And Cadmium

Association of lead and cadmium exposure with kidney stone incidence: A study on the non-occupational population in Nandan of China

2021 ◽  
Vol 68 ◽  
pp. 126852
Author(s):  
Jiong-Li Huang ◽  
Zhao-Yu Mo ◽  
Zhong-You Li ◽  
Gui-Yun Liang ◽  
Hui-Lin Liu ◽  
...  
Keyword(s):  
Kidney Stone ◽  
Cadmium Exposure ◽  
Lead And Cadmium

The Effect Of Prenatal Lead And Cadmium Exposure On Development Of Atopy

2011 ◽  
Author(s):  
Ja hyeong Kim ◽  
Ki Won Oh ◽  
Joon Sung Kim ◽  
Kyung Yeon Lee ◽  
Sang Kyu Park ◽  
...  
Keyword(s):  
Cadmium Exposure ◽  
Lead And Cadmium

Human Placenta Development, Structure, and Organization in Relation to Function and Fetal Development

2015 ◽  
pp. 3-20
Author(s):  
Tore Henriksen ◽  
A Holme ◽  
H Horne ◽  
M Holm ◽  
T Michelsen
Keyword(s):  
Human Placenta ◽  
Fetal Development ◽  
Development Structure

scholarly journals Mercury, lead, and cadmium exposure via red blood cell transfusions in preterm infants

2019 ◽  
Vol 87 (4) ◽  
pp. 677-682 ◽  
Author(s):  
Alison J. Falck ◽  
Alexandre E. Medina ◽  
Justine Cummins-Oman ◽  
Dina El-Metwally ◽  
Cynthia F. Bearer
Keyword(s):  
Blood Cell ◽  
Preterm Infants ◽  
Red Blood Cell ◽  
Cadmium Exposure ◽  
Lead And Cadmium ◽  
Red Blood Cell Transfusions

scholarly journals Uptake of Cerium Dioxide Nanoparticles and Impact on Viability, Differentiation and Functions of Primary Trophoblast Cells from Human Placenta

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1309
Author(s):  
Margaux Nedder ◽  
Sonja Boland ◽  
Stéphanie Devineau ◽  
Amal Zerrad-Saadi ◽  
Jasmina Rogozarski ◽  
...  
Keyword(s):  
Human Placenta ◽  
Fetal Development ◽  
Cerium Dioxide ◽  
Endocrine Function ◽  
Time Dependency ◽  
Caspase Activation ◽  
Trophoblast Differentiation ◽  
Wide Range ◽  
The Impact ◽  
Pregnancy Hormones

The human placenta is at the interface between maternal and fetal circulations, and is crucial for fetal development. The nanoparticles of cerium dioxide (CeO2 NPs) from air pollution are an unevaluated risk during pregnancy. Assessing the consequences of placenta exposure to CeO2 NPs could contribute to a better understanding of NPs’ effect on the development and functions of the placenta and pregnancy outcome. We used primary villous cytotrophoblasts purified from term human placenta, with a wide range of CeO2 NPs concentrations (0.1–101 μg/cm2) and exposure time (24–72 h), to assess trophoblast uptake, toxicity and impact on trophoblast differentiation and endocrine function. We have shown the capacity of both cytotrophoblasts and syncytiotrophoblasts to internalize CeO2 NPs. CeO2 NPs affected trophoblast metabolic activity in a dose and time dependency, induced caspase activation and a LDH release in the absence of oxidative stress. CeO2 NPs decreased the fusion capacity of cytotrophoblasts to form a syncytiotrophoblast and disturbed secretion of the pregnancy hormones hCG, hPL, PlGF, P4 and E2, in accordance with NPs concentration. This is the first study on the impact of CeO2 NPs using human primary trophoblasts that decrypts their toxicity and impact on placental formation and functions.

Effects of chronic lead and cadmium exposure on blood pressure in occupationally exposed workers

1994 ◽  
Vol 41 (3) ◽  
pp. 269-278 ◽  
Author(s):  
M. Schuhmacher ◽  
M. A. Bosque ◽  
J. L. Domingo ◽  
J. Corbella
Keyword(s):  
Blood Pressure ◽  
Cadmium Exposure ◽  
Lead And Cadmium ◽  
Exposed Workers ◽  
Occupationally Exposed

PERMEABILITY OF HUMAN PLACENTA TO PROGESTERONE-4-14C IN THE MIDDLE OF PREGNANCY

1962 ◽  
Vol 39 (4) ◽  
pp. 506-512 ◽  
Author(s):  
O. Castrén ◽  
L. Hirvonen ◽  
S. Närvänen ◽  
K. Soiva
Keyword(s):  
Chronic Diseases ◽  
Human Placenta ◽  
In Utero ◽  
Radioactive Material ◽  
Radioactivity Level

ABSTRACT Four women who had been pregnant for 17–24 weeks and whose pregnancies had been interrupted with simultaneous sterilisation because of chronic diseases, were given 10–20 μc of progesterone-4-14C intravenously. The ether-soluble radioactive material in the plasma of the mothers decreased so rapidly that only one per cent of the original radioactivity remained after 10 minutes. Two to four specimens of blood were taken from each foetus in utero 2–15 minutes after the injection. Every specimen was found to contain an ether-soluble radioactive material. The radioactivity of the foetal plasma increased gradually and 5–10 minutes after the injection it reached the radioactivity level in the plasma of the mother.

Lead and cadmium exposure in children living around a coal-mining area in Yatağan, Turkey

2006 ◽  
Vol 22 (8) ◽  
pp. 357-362 ◽  
Author(s):  
Gulcin Yapici ◽  
Gunay Can ◽  
Ali Riza Kiziler ◽  
Birsen Aydemir ◽  
İsmail Hakki Timur ◽  
...  
Keyword(s):  
Coal Mining ◽  
Mining Area ◽  
Cadmium Exposure ◽  
Coal Mining Area ◽  
Lead And Cadmium

scholarly journals Comparison of Pure-Tone Average Methods for Estimation of Hearing Loss Caused by Environmental Exposure to Lead and Cadmium: Does the Pure-Tone Average Method Which Uses Low-Frequency Ranges Underestimate the Actual Hearing Loss Caused by Environmental Lead and Cadmium Exposure?

2018 ◽  
Vol 23 (5) ◽  
pp. 259-269 ◽  
Author(s):  
Da-An Huh ◽  
Yun-Hee Choi ◽  
Myung Sun Ji ◽  
Kyong Whan Moon ◽  
Seok J. Yoon ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Environmental Exposure ◽  
High Frequency ◽  
Pure Tone ◽  
Low Frequency ◽  
Cadmium Exposure ◽  
Metal Exposure ◽  
Frequency Method ◽  
Pure Tone Average ◽  
Lead And Cadmium

Previous studies have reported that exposure to lead and cadmium can damage the inner ear receptor, which perceives high-frequency sounds. However, few studies have used the pure-tone average (PTA), including high-frequency ranges, for the estimation of hearing loss caused by lead and cadmium exposure. We estimated hearing loss using the PTA test, in low-frequency, speech frequency, and high-frequency ranges and compared the differences in the results using 3 PTA calculation methods. We analyzed the data of 2,387 participants, between the ages of 19 and 85 years, that were obtained from the Korea National Health and Nutrition Examination Survey (KNHANES) of 2010–2012. A dose-response relationship between hearing loss and heavy metal exposure was observed in the high-frequency method after adjustment for confounding factors. When using the high-frequency PTA, it was found that doubling of the levels of lead and cadmium in the blood was associated with a 1.88- (95% CI 1.11–3.17) and 1.89-fold (95% CI 1.02–3.50) increase in the OR for hearing loss. In the case of the low-frequency and speech frequency PTA, however, there were no significant relationships between hearing loss and the concentrations of lead and cadmium in the blood. The outcomes of the present study suggest that the estimation of hearing loss caused by environmental exposure to lead and cadmium is affected by the frequencies used in the PTA calculation.

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