Characterization of microbial community and antibiotic resistance genes in activated sludge under tetracycline and sulfamethoxazole selection pressure

2016 ◽  
Vol 571 ◽  
pp. 479-486 ◽  
Author(s):  
Yingying Zhang ◽  
Jinju Geng ◽  
Haijun Ma ◽  
Hongqiang Ren ◽  
Ke Xu ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Microbial Community ◽  
Activated Sludge ◽  
Resistance Genes ◽  
Selection Pressure ◽  
Antibiotic Resistance Genes

PAHs accelerate the propagation of antibiotic resistance genes in coastal water microbial community

2017 ◽  
Vol 231 ◽  
pp. 1145-1152 ◽  
Author(s):  
Jing Wang ◽  
Jing Wang ◽  
Zelong Zhao ◽  
Jingwen Chen ◽  
Hong Lu ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Microbial Community ◽  
Coastal Water ◽  
Resistance Genes ◽  
Antibiotic Resistance Genes

scholarly journals Characterization of a Multiresistant Mosaic Plasmid from a Fish Farm Sediment Exiguobacterium sp. Isolate Reveals Aggregation of Functional Clinic-Associated Antibiotic Resistance Genes

2013 ◽  
Vol 80 (4) ◽  
pp. 1482-1488 ◽  
Author(s):  
Jing Yang ◽  
Chao Wang ◽  
Jinyu Wu ◽  
Li Liu ◽  
Gang Zhang ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Resistance Genes ◽  
Antibiotic Resistance Genes ◽  
Mobile Elements ◽  
Fish Farms ◽  
Significant Similarity ◽  
Content Type ◽  
Genes Encoding ◽  
The Mean

ABSTRACTThe genusExiguobacteriumcan adapt readily to, and survive in, diverse environments. Our study demonstrated thatExiguobacteriumsp. strain S3-2, isolated from marine sediment, is resistant to five antibiotics. The plasmid pMC1 in this strain carries seven putative resistance genes. We functionally characterized these resistance genes inEscherichia coli, and genes encoding dihydrofolate reductase and macrolide phosphotransferase were considered novel resistance genes based on their low similarities to known resistance genes. The plasmid G+C content distribution was highly heterogeneous. Only the G+C content of one block, which shared significant similarity with a plasmid fromExiguobacterium arabatum, fit well with the mean G+C content of the host. The remainder of the plasmid was composed of mobile elements with a markedly lower G+C ratio than the host. Interestingly, five mobile elements located on pMC1 showed significant similarities to sequences found in pathogens. Our data provided an example of the link between resistance genes in strains from the environment and the clinic and revealed the aggregation of antibiotic resistance genes in bacteria isolated from fish farms.

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