Monitoring oxygen saturation and heart rate in the early neonatal period

In order to assess the influence of course of pregnancy upon rate and rhythm of heartbeat of a baby in the early neonatal period of life, parameters of babies’ cardiac oscillators were described in terms of power spectral density function calculated for rows of 100-250 consecutive ECG RR-intervals registered during orthodox sleep. Correlation of heart rhythm characteristics, ECG patterns of a baby during first 5 days after delivery and parameters of pregnancy described both in terms of nosology and symptoms (122 parameters in total) were analyzed. 160 newborns were enrolled in the study. Drug abuse, impossi-bility to fill in the query form or informal consent, severe disease of baby, gestational age less than 28 weeks and/or body weight at birth less than 1500 grams were specified as major exclusion criteria. It was shown that preeclampsia during the first half of pregnancy and women’s illness, associated with body temperature higher than 38 degrees Celsius after 8 week of pregnancy are among major determinants of babies’ cardiac oscillator in the early neonatal period of life, but they don’t affect the ECG wave amplitude and the duration of PQ and QT intervals. Pregnancy complicated during the first half promotes bradycardia and high heart rate variability and pregnancy complicated during the second half promotes tachycardia and low heart rate variability in babies during at least 5 days after delivery. Hypothetical spatial models of pacemaker areas were proposed for cases of normal pregnancy, pregnancy complicated in the first half and pregnancy complicated in the second half.

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A Case of Congenital Glucose Galactose Malabsorption with a New Mutation in the SLC5A1 Gene

Journal of Pediatric Genetics ◽

10.1055/s-0040-1719161 ◽

2020 ◽

Author(s):

Hasan Akduman ◽

Dilek Dilli ◽

Serdar Ceylaner

Keyword(s):

Mutation Analysis ◽

Autosomal Recessive ◽

Glucose Transporter ◽

Neonatal Period ◽

Autosomal Recessive Disorder ◽

Homozygous Mutation ◽

New Mutation ◽

Early Neonatal Period ◽

Sodium Dependent ◽

Hypernatremic Dehydration

AbstractCongenital glucose-galactose malabsorption (CGGM) is an autosomal recessive disorder originating from an abnormal transporter mechanism in the intestines. It was sourced from a mutation in the SLC5A1 gene, which encodes a sodium-dependent glucose transporter. Here we report a 2-day-old girl with CGGM who presented with severe hypernatremic dehydration due to diarrhea beginning in the first hours of life. Mutation analysis revealed a novel homozygous mutation NM_000343.3 c.127G > A (p.Gly43Arg) in the SLC5A1 gene. Since CGGM can cause fatal diarrhea in the early neonatal period, timely diagnosis of the disease seems to be essential.

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The Effects of Passive and Active Smoking on Brachial and radial Blood Pressure and Some Other Physical Factors in Healthy Young Adults

Science Journal of University of Zakho ◽

10.25271/2017.5.3.394 ◽

2017 ◽

Vol 5 (3) ◽

pp. 259

Author(s):

Shireen H. Ramadhan ◽

Shamil K. Talal ◽

Wasfiya A. Moner

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Oxygen Saturation ◽

Oxygen Concentration ◽

Tobacco Smoke ◽

Blood Pressure Measurement ◽

Reference Level ◽

Physical Factors ◽

New Device ◽

Active Smoker

Tobacco smoke is enormously harmful to human health, thereâ€™s no safe way to smoke. The primary objective of this study is to analyze the role of tobacco smoke compounds and their ability to damage the cardiovascular system and, in particular, to interfere with blood pressure (Brachial and radial pressure), heart rate and partly on the percentage blood Oxygen saturation. A new device has been manufactured which is unique for measuring the level of smoke, to obtained privies readings, the device had fixed to the first reference level آ and starting up from it. The effect of smoking has been studied on (26) male passive (26) active smoker volunteer, (14) female passive and (14) female active smoker participants. The results has been showed that the blood pressure and heart rate has been increased with increasing the number of cigarettes in both genders for passive and active smokers. However, this effect for male was more pronounced comparing with females for passive and active smokers. In the case of oxygen saturation concentration percentage, for males the change of oxygen concentration percentage was not stable. In other words, it was fluctuated with the number of cigarettes. But for females the oxygen concentration was decreased but not too much. This means that this effect was not pronounced. this study found آ that the most pronounced effect has been shown by maleâ€™s comparison to females for both passive and active smokers. As well as in nonsmokerâ€™s males, the relation between heart rate and smoke level is inversely proportional. While in male and female smokers and female nonsmokers the relation is proportional. In all cases the relation between the smoke level and time of smoking is inversely proportional. Finally males& females are affected differently by tobacco use; the sensitivities to smoke for males are higher than in females for passive and active smokers in both brachial and radial blood pressure measurement.

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FEATURES OF CARDIORESPIRATORY ADAPTATION OF LATER PRETERM INFANTS IN THE EARLY NEONATAL PERIOD

World of Medicine and Biology ◽

10.26724/2079-8334-2018-4-66-100-103 ◽

2018 ◽

Vol 14 (66) ◽

pp. 100

Author(s):

G. A. Solovyova ◽

V. I. Pokhilko ◽

S. N. Tsvirenko ◽

N. I. Gasyuk ◽

Yu. Yu. Klimchuk

Keyword(s):

Preterm Infants ◽

Neonatal Period ◽

Early Neonatal Period

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Study To Check The Immediate Effect Of Pursed Lip Breathing Exercise Versus Relaxed Diaphragmatic Exercise On Heart Rate, Blood Pressure And Oxygen Saturation In Young Adults Of College Of Physiothera

International Journal of Scientific and Research Publications (IJSRP) ◽

10.29322/ijsrp.9.12.2019.p96113 ◽

2019 ◽

Vol 9 (12) ◽

pp. p96113

Author(s):

Shephali Singh ◽

Kavita Kaushal ◽

Simratjeet Kaur

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Young Adults ◽

Oxygen Saturation ◽

Breathing Exercise

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Accurate Detection of Heart Rate and Blood Oxygen Saturation in Reflective Photoplethysmography

2020 IEEE International Symposium on Signal Processing and Information Technology (ISSPIT) ◽

10.1109/isspit51521.2020.9408845 ◽

2020 ◽

Author(s):

Maria Krizea ◽

John Gialelis ◽

Anastasios Kladas ◽

Gerasimos Theodorou ◽

Grigoris Protopsaltis ◽

...

Keyword(s):

Heart Rate ◽

Oxygen Saturation ◽

Blood Oxygen ◽

Blood Oxygen Saturation ◽

Accurate Detection

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Neonatal wearable device for colorimetry-based real-time detection of jaundice with simultaneous sensing of vitals

Science Advances ◽

10.1126/sciadv.abe3793 ◽

2021 ◽

Vol 7 (10) ◽

pp. eabe3793

Author(s):

Go Inamori ◽

Umihiro Kamoto ◽

Fumika Nakamura ◽

Yutaka Isoda ◽

Azusa Uozumi ◽

...

Keyword(s):

Heart Rate ◽

Oxygen Saturation ◽

Neonatal Jaundice ◽

Treatment Approach ◽

Combined Treatment ◽

Simultaneous Detection ◽

Clinical Experiments ◽

Simultaneous Sensing ◽

Severe Hyperbilirubinemia ◽

Transcutaneous Bilirubinometer

Neonatal jaundice occurs in >80% of newborns in the first week of life owing to physiological hyperbilirubinemia. Severe hyperbilirubinemia could cause brain damage owing to its neurotoxicity, a state commonly known as kernicterus. Therefore, periodic bilirubin monitoring is essential to identify infants at-risk and to initiate treatment including phototherapy. However, devices for continuous measurements of bilirubin have not been developed yet. Here, we established a wearable transcutaneous bilirubinometer that also has oxygen saturation (SpO2) and heart rate (HR) sensing functionalities. Clinical experiments with neonates demonstrated the possibility of simultaneous detection of bilirubin, SpO2, and HR. Moreover, our device could consistently measure bilirubin during phototherapy. These results demonstrate the potential for development of a combined treatment approach with an automatic link via the wearable bilirubinometer and phototherapy device for optimization of the treatment of neonatal jaundice.

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