Characteristics of pregnancy as determinants of cardiac oscillator of a baby in the early neonatal period of life

2014 ◽  
Vol 5 (4) ◽  
pp. 77-84
Author(s):  
Ahmad Wakah ◽  
Irina Vladimirovna Solodkova ◽  
Tat’yana Leonidovna Kornishina ◽  
Elizaveta Viktorovna Malkina ◽  
Ol’ga Viktorovna Shadrina ◽  
...  

In order to assess the influence of course of pregnancy upon rate and rhythm of heartbeat of a baby in the early neonatal period of life, parameters of babies’ cardiac oscillators were described in terms of power spectral density function calculated for rows of 100-250 consecutive ECG RR-intervals registered during orthodox sleep. Correlation of heart rhythm characteristics, ECG patterns of a baby during first 5 days after delivery and parameters of pregnancy described both in terms of nosology and symptoms (122 parameters in total) were analyzed. 160 newborns were enrolled in the study. Drug abuse, impossi-bility to fill in the query form or informal consent, severe disease of baby, gestational age less than 28 weeks and/or body weight at birth less than 1500 grams were specified as major exclusion criteria. It was shown that preeclampsia during the first half of pregnancy and women’s illness, associated with body temperature higher than 38 degrees Celsius after 8 week of pregnancy are among major determinants of babies’ cardiac oscillator in the early neonatal period of life, but they don’t affect the ECG wave amplitude and the duration of PQ and QT intervals. Pregnancy complicated during the first half promotes bradycardia and high heart rate variability and pregnancy complicated during the second half promotes tachycardia and low heart rate variability in babies during at least 5 days after delivery. Hypothetical spatial models of pacemaker areas were proposed for cases of normal pregnancy, pregnancy complicated in the first half and pregnancy complicated in the second half.

2014 ◽  
Vol 66 (2) ◽  
pp. 425-432 ◽  
Author(s):  
M.S. Oliveira ◽  
R.A.L. Muzzi ◽  
R.B. Araújo ◽  
L.A.L. Muzzi ◽  
D.F. Ferreira ◽  
...  

Cardiac diseases promote alterations in the autonomic control of the heart, leading to an increase in heart rate and, as a result, a decrease in heart rate variability (HRV).The aim of this study was to evaluate if the development of heart failure secondary to degenerative mitral valve disease (DMVD) concurs with changes in autonomic modulation of heart rhythm which are assessed by long electrocardiography examination (Holter). Dogs were evaluated by clinical examination and echocardiography in order to be categorized into the following groups: Control (healthy; n=6), DMVD (disease without heart failure; n=8), and DMVD heart failure (disease with heart failure; n=13). Arrhythmias and frequency domain HRV were determined by Holter. Diseased animals, when compared to healthy, had significantly lower total power, which indicates overall HRV. DMVD heart failure dogs also showed other disturbances such as high incidence of supraventricular arrhythmias, high heart rate, little amount of pauses (2.0s long between consecutive heartbeats), longer time in tachycardia, shorter time in bradycardia, low high frequency (parasympathetic control), and high low frequency (sympathetic and parasympathetic control) when compared to control (p<0.05). In DMVD dogs, Holter-derived variables changed with the development of heart failure.


Author(s):  
K. Jensen-Urstad ◽  
B. Saltin ◽  
M. Ericson ◽  
N. Storck ◽  
M. Jensen-Urstad

2021 ◽  
Vol 29 (3) ◽  
pp. 369-378
Author(s):  
Aleksej A. Nizov ◽  
Aleksej I. Girivenko ◽  
Mihail M. Lapkin ◽  
Aleksej V. Borozdin ◽  
Yana A. Belenikina ◽  
...  

BACKGROUND: The search for rational methods of primary, secondary, and tertiary prevention of coronary heart disease. To date, there are several publications on heart rate variability in ischemic heart disease. AIM: To study the state of the regulatory systems in the organism of patients with acute coronary syndrome without ST segment elevation based on the heart rhythm, and their relationship with the clinical, biochemical and instrumental parameters of the disease. MATERIALS AND METHODS: The open comparative study included 76 patients (62 men, 14 women) of mean age, 61.0 0.9 years, who were admitted to the Emergency Cardiology Department diagnosed of acute coronary syndrome without ST segment elevation. On admission, cardiointervalometry was performed using Varicard 2.51 apparatus, and a number of clinical and biochemical parameters were evaluated RESULTS: Multiple correlations of parameters of heart rate variability and clinical, biochemical and instrumental parameters were observed. From this, a cluster analysis of cardiointervalometry was performed, thereby stratifying patients into five clusters. Two extreme variants of dysregulation of the heart rhythm correlated with instrumental and laboratory parameters. A marked increase in the activity of the subcortical nerve centers (maximal increase of the spectral power in the very low frequency range with the underlying reduction of SDNN) in cluster 1 was associated with reduction of the left ventricular ejection fraction: cluster 147.0 [40.0; 49.0], cluster 260.0 [58.0; 64.0], cluster 360.0 [52.5; 64.5] % (the data are presented in the form of median and interquartile range; Me [Q25; Q75], p 0,05). Cluster 5 showed significant reduction in SDNN (monotonous rhythm), combined with increased level of creatine phosphokinase (CPC): cluster 5446,0 [186.0; 782.0], cluster 4141.0 [98.0; 204.0] IU/l; Me [Q25; Q75], p 0.05) and MВ-fraction of creatine phosphokinase; cluster 532.0 [15.0; 45.0], 4 cluster 412.0 [9.0; 18.0] IU/l; Me [Q25; Q75], p 0.05). CONCLUSIONS: In patients with acute coronary syndrome without ST segment elevation, cluster analysis of parameters of heart rate variability identified different peculiarities of regulation of the heart rhythm. Pronounced strain of the regulatory systems of the body was found to be associated with signs of severe pathology: the predominance of VLF (spectral power of the curve enveloping a dynamic range of cardiointervals in the very low frequency range) in spectral analysis with an underlying reduced SDNN is characteristic of patients with a reduced ejection fraction, and a monotonous rhythm is characteristic of patients with an increased level of creatine phosphokinase and MB-fraction of creatine phosphokinase.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Meenakshi Chaswal ◽  
Raj Kapoor ◽  
Achla Batra ◽  
Savita Verma ◽  
Bhupendra S. Yadav

Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of autonomic functions was done by cardiovascular reflex tests and by analysis of heart rate variability (HRV). Cardiovascular reflex tests included deep breathing test (DBT) and lying to standing test (LST). HRV was analyzed in both time and frequency domain for quantifying the tone of autonomic nervous system to the heart. The time domain measures included standard deviation of normal R-R intervals (SDNN) and square root of mean squared differences of successive R-R intervals (RMSSD). In the frequency domain we measured total power (TP), high frequency (HF) power, low frequency (LF) power, and LF/HF ratio. Cardiovascular reflex tests showed a significant parasympathetic deficit in preeclamptic women. Among parameters of HRV, preeclamptic group had lower values of SDNN, RMSSD, TP, HF, and LF (ms2) and higher value of LF in normalised units along with high LF/HF ratio compared to normotensive pregnant and nonpregnant controls. Furthermore, normotensive pregnant women had lower values of SDNN, TP, and LF component in both absolute power and normalised units compared to nonpregnant females. The results confirm that normal pregnancy is associated with autonomic disturbances which get exaggerated in the state of preeclampsia.


2010 ◽  
Vol 105 (8) ◽  
pp. 1181-1185 ◽  
Author(s):  
Usman Zulfiqar ◽  
Donald A. Jurivich ◽  
Weihua Gao ◽  
Donald H. Singer

2012 ◽  
Vol 42 (3) ◽  
pp. 347-352 ◽  
Author(s):  
Mathias Baumert ◽  
Michal Javorka ◽  
Andrea Seeck ◽  
Renaldo Faber ◽  
Prashanthan Sanders ◽  
...  

Medicina ◽  
2009 ◽  
Vol 45 (3) ◽  
pp. 214 ◽  
Author(s):  
Sergejus Andruškevičius

The objective of this work was to study circadian rhythms of the indicators of the spectral analysis of the heart rate variability in case of depression. Materials and methods. A total of 37 patients, with a mean age of 46.7±10.3 years, were examined. According to the International Classification of Disease, 10th revision (ICD-10), endogenous depression was diagnosed for all of them (F 31.3–31.4, F 32.0–32.2, F 33.0–33.2). To assess the variability of the heart rhythm, the spectral analysis was used. The patients were examined at 1 AM, 7 AM, 1 PM, 7 PM prior to the beginning of treatment, following one week, and upon leaving the inpatient department. The control group consisted of 15 mentally healthy people. Results. Before the beginning of treatment, desynchronization of circadian rhythms of the indicators studied and the sleep-wake cycle, the increase in the spectrum power within lowfrequency (LF) range, and the decrease in the spectrum power within high-frequency (HF) range were observed. Reduction of depression symptoms was followed by resynchronization of the rhythms under study, with a spectrum power within LF range being increased and that within HF range – decreased. Conclusions. Changes in depression symptoms and chronobiological disorders testify to their close pathogenetic link.


Heart ◽  
2010 ◽  
Vol 97 (7) ◽  
pp. 544-550 ◽  
Author(s):  
N. L. Mills ◽  
A. E. Finlayson ◽  
M. C. Gonzalez ◽  
H. Tornqvist ◽  
S. Barath ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document