Magnetic field potential effects on the doxorubicin therapeutic activity in Ehrlich tumor growth

We consider the solutions of two integrodifferential equations in this work. These equations describe the ultra-low frequency waves in the dipol-like model of the magnetosphere in the gyrokinetic framework. The first one is reduced to the homogeneous, second kind Fredholm equation. This equation describes the structure of the parallel component of the magnetic field of drift-compression waves along the Earth’s magnetic field. The second equation is reduced to the inhomogeneous, second kind Fredholm equation. This equation describes the field-aligned structure of the parallel electric field potential of Alfvén waves. Both integral equations are solved numerically.

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INHIBITION OF EHRLICH TUMOR GROWTH IN MICE BY ELECTRIC INTERFERENCE THERAPY (IN VIVO STUDIES)

Electromagnetic Biology and Medicine ◽

10.1081/jbc-120015999 ◽

2002 ◽

Vol 21 (3) ◽

pp. 255-268 ◽

Cited By ~ 8

Author(s):

Magdy M. Ghannam ◽

R. H. El-Gebaly ◽

M. H. Gaber ◽

Fadel M. Ali

Keyword(s):

Tumor Growth ◽

In Vivo Studies ◽

Ehrlich Tumor

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Effect of a submaxillary gland extract on Ehrlich tumor growth in mice

Brazilian Journal of Medical and Biological Research ◽

10.1590/s0100-879x1999001000005 ◽

1999 ◽

Vol 32 (10) ◽

pp. 1205-1209 ◽

Cited By ~ 3

Author(s):

P. Weill ◽

R. Frussa-Filho ◽

L.V. Bonamin

Keyword(s):

Tumor Growth ◽

Submaxillary Gland ◽

Ehrlich Tumor ◽

Gland Extract

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Subcutaneous administration of ketoprofen delays Ehrlich solid tumor growth in mice

Arquivo Brasileiro de Medicina Veterinária e Zootecnia ◽

10.1590/1678-6729 ◽

2014 ◽

Vol 66 (5) ◽

pp. 1376-1382 ◽

Cited By ~ 1

Author(s):

C.M. Souza ◽

P.A. Auler ◽

D.C. Reis ◽

G.E. Lavalle ◽

E. Ferreira ◽

...

Keyword(s):

Cell Proliferation ◽

Tumor Growth ◽

Solid Tumor ◽

Cellular Proliferation ◽

Subcutaneous Administration ◽

Physiological Saline ◽

Malignant Cell ◽

Control Group ◽

Ehrlich Tumor ◽

Anti Inflammatory

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) has proven to exert anti-inflammatory, anti-proliferative and anti-angiogenic activities in both neoplastic and non-neoplastic conditions. We investigated the effects of this compound on tumor development in Swiss mice previously inoculated with Ehrlich tumor cells. To carry out this study the solid tumor was obtained from cells of the ascites fluid of Ehrlich tumor re-suspended in physiological saline to give 2.5x106cells in 0.05mL. After tumor inoculation, the animals were separated into two groups (n = 10). The animals treated with ketoprofen 0.1µg/100µL/animal were injected intraperitoneally at intervals of 24h for 10 consecutive days. Animals from the control group received saline. At the end of the experiment the mice were killed and the tumor removed. We analyzed tumor growth, histomorphological and immunohistochemical characteristics for CDC47 (cellular proliferation marker) and for CD31 (blood vessel marker). Animals treated with the ketoprofen 0.1µg/100µL/animal showed lower tumor growth. The treatment did not significantly influence the size of the areas of cancer, inflammation, necrosis and hemorrhage. Moreover, lower rates of tumor cell proliferation were observed in animals treated with ketoprofen compared with the untreated control group. The participation of ketoprofen in controlling tumor malignant cell proliferation would open prospects for its use in clinical and antineoplasic therapy.

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Mathematical Modeling of Treatment Effect on Tumor Growth and Blood Flow through a Channel with Magnetic Field

Journal of Advances in Mathematics and Computer Science ◽

10.9734/jamcs/2021/v36i730385 ◽

2021 ◽

pp. 66-79

Author(s):

K. W. Bunonyo ◽

C. U. Amadi

Keyword(s):

Magnetic Field ◽

Differential Equation ◽

Ordinary Differential Equation ◽

Blood Flow ◽

Tumor Growth ◽

Blood Velocity ◽

Frequency Parameter ◽

Womersley Number ◽

Permeability Parameter ◽

Flow Through

In this research, we investigated the effect of tumor growth on blood flow through a micro channel by formulated the governing model with the assumption that blood is an incompressible, eclectrially conducting fluid which flow is caused by the pumping action of the heart and suction. The governing model was scaled using some dimensionless variables and the region of the tumor was obtained from Dominguez [1] which was incorporated in our model. The model is further reduced to an ordinary differential equation using a perturbation condition. However, the ordinary differential equation was solved using method of undermined coefficients, and the constants coefficients obtained via matrix method. Furthermore, the simulation to study the effect of the pertinent parameters was done suing computation software called Mathematica. It is seen in our investigation that the entering parameters such as magnetic field parameter, the Reynolds number, womersley number, oscillatory frequency parameter, and permeability parameter affect the blood velocity profile in decreasing and increasing fashion.

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Cohabitation with a Sick Cage Mate: Effects on Ascitic Form of Ehrlich Tumor Growth and Macrophage Activity

NeuroImmunoModulation ◽

10.1159/000121284 ◽

2007 ◽

Vol 14 (6) ◽

pp. 297-303 ◽

Cited By ~ 11

Author(s):

Glaucie Jussilane Alves ◽

Luciana Vismari ◽

João Palermo-Neto

Keyword(s):

Tumor Growth ◽

Ehrlich Tumor ◽

Macrophage Activity

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The Ehrlich Tumor Induces Pain-Like Behavior in Mice: A Novel Model of Cancer Pain for Pathophysiological Studies and Pharmacological Screening

BioMed Research International ◽

10.1155/2013/624815 ◽

2013 ◽

Vol 2013 ◽

pp. 1-12 ◽

Cited By ~ 15

Author(s):

Cassia Calixto-Campos ◽

Ana C. Zarpelon ◽

Mab Corrêa ◽

Renato D. R. Cardoso ◽

Felipe A. Pinho-Ribeiro ◽

...

Keyword(s):

Tumor Growth ◽

Cancer Pain ◽

Tumor Cells ◽

Tricyclic Antidepressant ◽

Mechanical Hyperalgesia ◽

Cyclooxygenase Inhibitor ◽

Paw Edema ◽

Ehrlich Tumor ◽

Novel Model ◽

Ehrlich Tumor Cells

The Ehrlich tumor is a mammary adenocarcinoma of mice that can be developed in solid and ascitic forms depending on its administration in tissues or cavities, respectively. The present study investigates whether the subcutaneous plantar administration of the Ehrlich tumor cells induces pain-like behavior and initial pharmacological susceptibility characteristics. The Ehrlich tumor cells (1 × 104–107cells) induced dose-dependent mechanical hyperalgesia (electronic version of the von Frey filaments), paw edema/tumor growth (caliper), and flinches compared with the saline group between days 2 and 12. There was no difference between doses of cells regarding thermal hyperalgesia in the hot-plate test. Indomethacin (a cyclooxygenase inhibitor) and amitriptyline hydrochloride (a tricyclic antidepressant) treatments did not affect flinches or thermal and mechanical hyperalgesia. On the other hand, morphine (an opioid) inhibited the flinch behavior and the thermal and mechanical hyperalgesia. These effects of morphine on pain-like behavior were prevented by naloxone (an opioid receptor antagonist) treatment. None of the treatments affected paw edema/tumor growth. The results showed that, in addition to tumor growth, administration of the Ehrlich tumor cells may represent a novel model for the study of cancer pain, specially the pain that is susceptible to treatment with opioids, but not to cyclooxygenase inhibitor or to tricyclic antidepressant.

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The bradykinin B1 receptor antagonist R-954 inhibits Ehrlich tumor growth in rodents

Peptides ◽

10.1016/j.peptides.2011.07.023 ◽

2011 ◽

Vol 32 (9) ◽

pp. 1849-1854 ◽

Cited By ~ 9

Author(s):

Patricia Dias Fernandes ◽

Niele de Matos Gomes ◽

Pierre Sirois

Keyword(s):

Tumor Growth ◽

Receptor Antagonist ◽

Ehrlich Tumor ◽

B1 Receptor ◽

Bradykinin B1 Receptor

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THE USE OF POISSON’S RELATION FOR THE EXTRACTION OF PSEUDOTOTAL MAGNETIC FIELD INTENSITY FROM GRAVITY OBSERVATIONS

Geophysics ◽

10.1190/1.1440195 ◽

1971 ◽

Vol 36 (3) ◽

pp. 605-608 ◽

Cited By ~ 6

Author(s):

Edwin S. Robinson

Keyword(s):

Magnetic Field ◽

Gravity Field ◽

Field Data ◽

Field Potential ◽

Geological Structure ◽

Common Source ◽

Uniform Density ◽

Practical Applications ◽

Uniform Magnetization ◽

Gravity Fields

Investigation of geological structure by gravimetric and magnetic field surveys requires consideration of relationships between gravity anomaly and magnetic anomaly generating sources. The possibility of using Poisson’s Relation to examine magnetic and gravity fields related to a common source is intriguing. This relation is expressed as follows: [Formula: see text] (1) where A (x, y, z) is the magnetic field potential and U (x, y, z) is the gravity field potential at a point in space due to a source of uniform density ρ and uniform magnetization I in the direction α. This expression has been used to derive magnetic anomalies over idealized forms (Nettleton, 1940) and, by Baranov (1957), to extract pseudogravity fields from magnetic field data. The purpose of this paper is to develop an expression for extracting a pseudomagnetic field from gravity field data and to examine the practical applications of this expression.

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