Immunoassay detection using functionalized gold nanoparticle probes coupled with resonance Rayleigh scattering

2009 ◽  
Vol 135 (2) ◽  
pp. 603-609 ◽  
Author(s):  
Huai-Hong Cai ◽  
Pei-Hui Yang ◽  
Jing Feng ◽  
Jiye Cai
2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Haidong Wang ◽  
Chongning Li ◽  
Yanghe Luo ◽  
Zhiliang Jiang

The gold nanoparticle reaction of HAuCl4-H2O2 was very slow under 60°C, and the as-prepared graphene oxide nanoribbons (GONRs) exhibited strong catalysis of the reaction to form gold nanoparticles (AuNP) that appeared a resonance Rayleigh scattering (RRS) peak at 550 nm. Upon addition of potassium pyroantimonate (PA) ligand, it was adsorbed on the GONRs surface to inhibit the catalysis to cause the RRS peak decreasing. When the analyte of Na+ was added, the coordination reaction between PA and Na+ took place to form the stable complexes of [Na2(PA)] to release free GONRs catalyst that resulted in the RRS peak increasing linearly. Accordingly, a new and sensitive RRS method for Na+ was established, with a linear range of 0.69-25.8 nmol/L and a detection limit of 0.35 nmol/L Na+.


RSC Advances ◽  
2015 ◽  
Vol 5 (12) ◽  
pp. 9272-9277 ◽  
Author(s):  
Yaohui Wang ◽  
Xinghui Zhang ◽  
Qingye Liu ◽  
Guiqing Wen ◽  
Aihui Liang ◽  
...  

A sensitive graphene oxide/nanogold surface plasmon resonance Rayleigh scattering-energy transfer analytical platform was developed for detection of iodide and H2O2.


2007 ◽  
Vol 598 (2) ◽  
pp. 304-311 ◽  
Author(s):  
Shao Pu Liu ◽  
You Qiu He ◽  
Zhong Fang Liu ◽  
Ling Kong ◽  
Qun Min Lu

2013 ◽  
Vol 647 ◽  
pp. 618-622
Author(s):  
Zhi Liang Jiang ◽  
Chen Yin Lin ◽  
Ai Hui Liang

Aptamer was modified the gold nanoparticle (AuNP) to form stable aptamer-AuNP probe that was not gathered in the pH 7.2 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid (HEPES) buffer solution and in the presence of NaCl. The Ag+ react with the aptamer-AuNP probe to fold a hairpin structure complex of Ag+-aptamer and release AuNPs that were aggregated to large particles, which lead to resonance Rayleigh scattering (RRS) peak at 596 nm enhancement. The enhanced value ΔI596nm is linear to Ag + concentration in the range of 6.7×10-8-1.33×10-6 mol/L. Thus, a new RRS methods were proposed for detection of Ag+, with high sensitivity, good selectivity and simplicity.


2018 ◽  
Vol 10 (24) ◽  
pp. 2910-2916 ◽  
Author(s):  
Junbo Li ◽  
Yanqiang Yang ◽  
Jinghua Wang ◽  
Bing Zhang ◽  
Honghong Chang ◽  
...  

A facile and effective Apt functionalized gold nanoparticle based RRS assay for the sensitive and selective detection of the EGFR.


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