Effects of surgically induced weight loss by Roux-en-Y gastric bypass on osteocalcin

2013 ◽  
Vol 9 (6) ◽  
pp. 950-955 ◽  
Author(s):  
Raelene E. Maser ◽  
M. James Lenhard ◽  
Prabhakaran (Babu) Balagopal ◽  
Paul Kolm ◽  
Michael B. Peters
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Surgically Induced

scholarly journals Surgically induced weight loss by gastric bypass improves non alcoholic fatty liver disease in morbid obese patients

2012 ◽  
Vol 4 (12) ◽  
pp. 382 ◽  
Author(s):  
Víctor Vargas ◽  
Helena Allende ◽  
Albert Lecube ◽  
Maria Teresa Salcedo ◽  
Juan A Baena-Fustegueras ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Obese Patients ◽  
Alcoholic Fatty Liver ◽  
Morbid Obese ◽  
Surgically Induced ◽  
Alcoholic Fatty Liver Disease

scholarly journals Effects of gastric bypass on the GH/IGF-I axis in severe obesity – and a comparison with GH deficiency

2006 ◽  
Vol 154 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Britt Edén Engström ◽  
Pia Burman ◽  
Camilla Holdstock ◽  
Margareta Öhrvall ◽  
Magnus Sundbom ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Severe Obesity ◽  
Gh Deficiency ◽  
Normal Weight ◽  
Obese Women ◽  
Serum Samples ◽  
Gh Secretion ◽  
Igf I ◽  
Surgically Induced

Objective: Overfeeding suppresses GH secretion and makes evaluation of a suspected GH deficiency (GHD) difficult. In normal weight subjects, gender is known to influence GH concentrations, which is most apparent in the ambulatory, morning-fasted state. In this study, we examined the GH/IGF-I axis in obese men and women and the effect of surgically induced weight loss. Design: Sixty-three subjects (body mass index (BMI) 45 ± 6 kg/m2; 54 women, 9 men) were studied prior to, and 6 and 12 months following Roux-en-Y gastric bypass (RYGBP) surgery. Fifty-four patients with classic GHD (BMI 27 ± 6 kg/m2; 35 men, 19 women) were included for comparison. Methods: Hormones were analysed in fasting morning serum samples. Results: RYGBP resulted in a decreased BMI to 35 ± kg/m2 at 6 months and 32 ± 6 kg/m2 at 12 months. GH and IGF-I increased at 6 months in the women and at 12 months in both sexes by ≥ 300 and 11% respectively. Prior to RYGBP, GH concentrations were low in the obese men and similar to those of GHD men (mean 0.09 mU/l). Obese women had tenfold higher values than obese men and sevenfold higher than GHD women. IGF-I levels were in the low reference range in the obese and below −2 s.d. for age in 13%. Conclusions: Surgically induced weight loss partially restores GH secretion. Despite a marked suppression of GH values, a gender influence is maintained in severe obesity. In obese women, single morning GH and IGF-I values seem sufficient to exclude a suspicion of classic GHD.

Effects of surgically induced weight loss by Roux-en-Y gastric bypass on cardiovascular autonomic nerve function

2013 ◽  
Vol 9 (2) ◽  
pp. 221-226 ◽  
Author(s):  
Raelene E. Maser ◽  
M. James Lenhard ◽  
Michael B. Peters ◽  
Isaias Irgau ◽  
Gail M. Wynn
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Autonomic Nerve ◽  
Nerve Function ◽  
Autonomic Nerve Function ◽  
Surgically Induced

Gastric Bypass Trumps Band for Weight Loss

2008 ◽  
Vol 41 (1) ◽  
pp. 30-31
Author(s):  
FRAN LOWRY
Keyword(s):  
Weight Loss ◽  
Gastric Bypass

Thyroid function and weight loss after Roux-en-Y gastric bypass: observational study

2017 ◽  
Author(s):  
de Carvalho Gisah Amaral ◽  
Cleo Mesa ◽  
Rodrigo Strobel ◽  
Paula Carolina Dambros Granzotto
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Observational Study ◽  
Thyroid Function

Weight loss one year after laparoscopic roux-en-Y gastric bypass is not dependent on the type of gastrojejunal anastomosis

2021 ◽  
Author(s):  
Fernando Munoz-Flores ◽  
Jorge Humberto Rodriguez-Quintero ◽  
David Pechman ◽  
Collin Creange ◽  
Ariela Zenilman ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Gastrojejunal Anastomosis ◽  
One Year

scholarly journals Factors determining chance of type 2 diabetes remission after Roux-en-Y gastric bypass surgery: a nationwide cohort study in 8057 Swedish patients

2021 ◽  
Vol 9 (1) ◽  
pp. e002033
Author(s):  
Erik Stenberg ◽  
Torsten Olbers ◽  
Yang Cao ◽  
Magnus Sundbom ◽  
Anders Jans ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Weight Loss ◽  
Gastric Bypass ◽  
Metabolic Surgery ◽  
First Generation ◽  
Hemoglobin A1c ◽  
Diabetes Remission ◽  
Factors Associated ◽  
Generation Immigrant

IntroductionBariatric and metabolic surgery is an effective treatment option for type 2 diabetes (T2D). Increased knowledge regarding factors associated with diabetes remission is essential in individual decision making and could guide postoperative care. Therefore, we aimed to explore factors known to affect the chance of achieving diabetes remission after bariatric and metabolic surgery and to further investigate the impact of socioeconomic factors.Research design and methodsIn this nationwide study, we assessed all patients with T2D who underwent Roux-en-Y gastric bypass (RYGB) surgery between 2007 and 2015 in the Scandinavian Obesity Surgery Registry. Remission was defined as absence of antidiabetic medication for T2D 2 years after surgery. Multivariable logistic regression was used to evaluate factors associated with diabetes remission, with missing data handled by multiple imputations.ResultsA total of 8057 patients were included. Mean age±SD was 47.4±10.1 years, mean body mass index 42.2±5.7 kg/m2, mean hemoglobin A1c 59.0±17.33, and 61.7% (n=4970) were women. Two years after surgery, 6211 (77.1%) patients achieved T2D remission. Preoperative insulin treatment (OR 0.26, 95% CI 0.22 to 0.30), first-generation immigrant (OR 0.66, 95% CI 0.57 to 0.77), duration of T2D (OR 0.89, 95% CI 0.88 to 0.90), dyslipidemia (OR 0.71, 95% CI 0.62 to 0.81), age (OR 0.97, 95% CI 0.96 to 0.97), and high glycosylated hemoglobin A1c (HbA1c) (OR 0.99, 95% CI 0.98 to 0.99) were all associated with lower T2D remission rate. In contrast, residence in a medium-sized (OR 1.39, 95% CI 1.20 to 1.61) or small (OR 1.46, 95% CI 1.25 to 1.71) town and percentage of total weight loss (OR 1.04, 95% CI 1.03 to 1.04) were associated with higher remission rates.ConclusionAmong patients with T2D undergoing RYGB surgery, increasing age, HbA1c, and diabetes duration decreased the chance of reaching diabetes remission without cut-offs, while postoperative weight loss demonstrated a positive linear association. In addition, being a first-generation immigrant and living in a large city were socioeconomic factors having a negative association.

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