Short applications of very low-magnitude vibrations attenuate expansion of the intervertebral disc during extended bed rest

2009 ◽  
Vol 9 (6) ◽  
pp. 470-477 ◽  
Author(s):  
Nilsson Holguin ◽  
Jesse Muir ◽  
Clinton Rubin ◽  
Stefan Judex
Keyword(s):  
Intervertebral Disc ◽  
Bed Rest ◽  
Low Magnitude

Low-magnitude whole body vibration with resistive exercise as a countermeasure against cardiovascular deconditioning after 60 days of head-down bed rest

2011 ◽  
Vol 301 (6) ◽  
pp. R1748-R1754 ◽  
Author(s):  
Mickael Coupé ◽  
Ming Yuan ◽  
Claire Demiot ◽  
Yanqiang Q. Bai ◽  
Shizhong Z. Jiang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Baroreflex Sensitivity ◽  
Whole Body Vibration ◽  
Bed Rest ◽  
Whole Body ◽  
Resistive Exercise ◽  
Body Vibration ◽  
Cardiovascular Deconditioning ◽  
Low Magnitude

Whole body vibration with resistive exercise is a promising countermeasure against some weightlessness-induced dysfunctions. Our objective was to study whether the combination of low-magnitude whole body vibration with a resistive exercise can prevent the cardiovascular deconditioning induced by a nonstrict 60-day head-down bed rest (Earth Star International Bed Rest Experiment Project). Fourteen healthy men participated in this study. We recorded electrocardiograms and blood pressure waves by means of a noninvasive beat-by-beat measurement system (Cardiospace, integrated by Centre National d'Etudes Spatiales and Astronaut Center of China) during an orthostatic test (20 min of 75-degree head-up tilt test) before and immediately after bed rest. We estimated heart rate, blood pressure, cardiac output, stroke volume, total peripheral resistance, baroreflex sensitivity, and heart rate variability. Low-magnitude whole body vibration with resistive exercise prevented an increase of the sympathetic index (reflecting the sympathovagal balance of cardiac autonomic control) and limited the decrease of the spontaneous baroreflex sensitivity induced by 60 days of head-down bed rest. However, this countermeasure had very little effect on cardiac hemodynamics and did not improve the orthostatic tolerance. This combined countermeasure did not efficiently prevent orthostatic intolerance but prevents changes in the autonomic nervous system associated with cardiovascular deconditioning. The underlying mechanisms remain hypothetical but might involve cutaneous and muscular mechanoreceptors.

scholarly journals Changes in intervertebral disc morphology persist 5 mo after 21-day bed rest

2011 ◽  
Vol 111 (5) ◽  
pp. 1304-1314 ◽  
Author(s):  
Daniel L. Belavý ◽  
P. Martin Bansmann ◽  
Gisela Böhme ◽  
Petra Frings-Meuthen ◽  
Martina Heer ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Signal Intensity ◽  
Muscle Activation ◽  
Bed Rest ◽  
Intervertebral Discs ◽  
Erector Spinae ◽  
Cross Sectional ◽  
Intensity Changes ◽  
Lumbar Muscle ◽  
Muscle Cross Sectional Area

As part of the nutrition-countermeasures (NUC) study in Cologne, Germany in 2010, seven healthy male subjects underwent 21 days of head-down tilt bed rest and returned 153 days later to undergo a second bout of 21-day bed rest. As part of this model, we aimed to examine the recovery of the lumbar intervertebral discs and muscle cross-sectional area (CSA) after bed rest using magnetic resonance imaging and conduct a pilot study on the effects of bed rest in lumbar muscle activation, as measured by signal intensity changes in T2-weighted images after a standardized isometric spinal extension loading task. The changes in intervertebral disc volume, anterior and posterior disc height, and intervertebral length seen after bed rest did not return to prebed-rest values 153 days later. While recovery of muscle CSA occurred after bed rest, increases ( P ≤ 0.016) in multifidus, psoas, and quadratus lumborum muscle CSA were seen 153 days after bed rest. A trend was seen for greater activation of the erector spinae and multifidus muscles in the standardized loading task after bed rest. Greater reductions of multifidus and psoas CSA muscle and greater increases in multifidus signal intensity with loading were associated with incidence of low back pain in the first 28 days after bed rest ( P ≤ 0.044). The current study contributes to our understanding of the recovery of the lumbar spine after 21-day bed rest, and the main finding was that a decrease in spinal extensor muscle CSA recovers within 5 mo after bed rest but that changes in the intervertebral discs persist.

scholarly journals Lumbar muscle atrophy and increased relative intramuscular lipid concentration are not mitigated by daily artificial gravity after 60-day head-down tilt bedrest

2021 ◽  
Author(s):  
Enrico De Martino ◽  
Julie Hides ◽  
James M. Elliott ◽  
Mark Hoggarth ◽  
Jochen Zange ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Intervertebral Disc ◽  
Muscle Atrophy ◽  
Bed Rest ◽  
Artificial Gravity ◽  
Lipid Concentration ◽  
Muscle Composition ◽  
Disc Area ◽  
Intramuscular Lipid ◽  
Water Ratio

Exposure to axial unloading induces adaptations in paraspinal muscles, as shown after spaceflights. This study investigated whether daily exposure to artificial gravity (AG) mitigated lumbar spine flattening and muscle atrophy associated with 60-day head-down tilt (HDT) bed rest (Earth-based space analogue). Twenty-four healthy individuals participated in the study: Eight received 30 minutes continuous AG; eight received 6x5 minutes AG, interspersed with rest periods; eight received no AG exposure (control group). Magnetic Resonance Imaging (MRI) of the lumbopelvic region was conducted at baseline (BDC) and at day 59 of HDT (HDT59). T1-weighted images were used to assess morphology of the lumbar spine (spinal length, intervertebral disc angles, disc area) and volumes of the lumbar multifidus (LM), lumbar erector spinae (LES), quadratus lumborum (QL), and psoas major (PM) muscles from L1/L2 to L5/S1 vertebral levels. A chemical shift-based 2‐point lipid/water Dixon sequence was used to evaluate muscle composition. Results showed that: spinal length and disc area increased (P<0.05); intervertebral disc angles (P<0.05) and muscle volumes of LM, LES, and QL reduced (P<0.01); and fat/water ratio for the LM and LES muscles increased (P<0.01) after HDT59 in all groups. Neither of the AG protocols mitigated the lumbar spinal deconditioning induced by HDT bed rest. The increase in lipid/water ratio in LM and LES muscles indicates an increased relative intramuscular lipid concentration. Altered muscle composition in atrophied muscles may impair lumbar spine function after body unloading, which could increase injury risk to vulnerable soft tissues. This relationship needs further investigation.

Changes in Intervertebral Disc Cross-Sectional Area With Bed Rest and Space Flight

Spine ◽  
1994 ◽  
Vol 19 (7) ◽  
pp. 812-817 ◽  
Author(s):  
Adrian D. LeBlanc ◽  
Harlan J. Evans ◽  
Victor S. Schneider ◽  
Richard E. Wendt ◽  
Thomas D. Hedrick
Keyword(s):  
Intervertebral Disc ◽  
Space Flight ◽  
Bed Rest ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional

scholarly journals Low magnitude of tensile stress represses the inflammatory response at intervertebral disc in rats

2015 ◽  
Vol 10 (1) ◽  
pp. 26
Author(s):  
Chao Han ◽  
Xin-long Ma ◽  
Tao Wang ◽  
Jian-xiong Ma ◽  
Peng Tian ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Tensile Stress ◽  
Intervertebral Disc ◽  
Low Magnitude

No effect of artificial gravity on lung function with exercise training during head-down bed rest

2015 ◽  
pp. 1-7
Author(s):  
Longxiang Su ◽  
Yinghua Guo ◽  
Yajuan Wang ◽  
Delong Wang ◽  
Changting Liu
Keyword(s):  
Lung Function ◽  
Pulse Rate ◽  
Vital Capacity ◽  
Pulmonary Ventilation ◽  
Bed Rest ◽  
Forced Expiratory Volume ◽  
Observation Time ◽  
Artificial Gravity ◽  
Postural Changes ◽  
Expiratory Flow

AbstractTo explore the effectiveness of microgravity simulated by head-down bed rest (HDBR) and artificial gravity (AG) with exercise on lung function. Twenty-four volunteers were randomly divided into control and exercise countermeasure (CM) groups for 96 h of 6° HDBR. Comparisons of pulse rate, pulse oxygen saturation (SpO2) and lung function were made between these two groups at 0, 24, 48, 72, 96 h. Compared with the sitting position, inspiratory capacity and respiratory reserve volume were significantly higher than before HDBR (0° position) (P&lt; 0.05). Vital capacity, expiratory reserve volume, forced vital capacity, forced expiratory volume in 1 s, forced inspiratory vital capacity, forced inspiratory volume in 1 s, forced expiratory flow at 25, 50 and 75%, maximal mid-expiratory flow and peak expiratory flow were all significantly lower than those before HDBR (P&lt; 0.05). Neither control nor CM groups showed significant differences in the pulse rate, SpO2, pulmonary volume and pulmonary ventilation function over the HDBR observation time. Postural changes can lead to variation in lung volume and ventilation function, but a HDBR model induced no changes in pulmonary function and therefore should not be used to study AG CMs.

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