Thin hydroxyapatite coating on titanium fabricated by chemical coating process using calcium phosphate slurry

In this study, the influence of employing three different sodium hydroxide (NaOH) pretreatment concentration (1, 3 and 5M) and two cleaning methods (Ultrasonic or Rinse) used in rapid biomimetic coating process on phase composition, function groups, thickness, amount and microstructure of the resulted coating was carried out. Regardless of process parameters, x-ray diffraction and Fourier transform infrared spectroscopy revealed that the all coating mainly comprised octacalcium phosphate and hydroxyapatite as main phases while the microstructure similarly consisted of sharp and interconnected plate-like calcium phosphate (CaP) crystals vertically grown on the surface of titanium. However, the change in sodium hydroxide concentration in pretreatment step and cleaning method influenced the weight change after pretreatment, coating continuity and uniformity, but not the weight change after coating. This could be related to amount of the amorphous alkali gel layer formed during pretreatment step which influenced the rate of coating formation in rapid biomimetic coating process.

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Effect of nano-hydroxyapatite coating on the osteoinductivity of porous biphasic calcium phosphate ceramics

BMC Musculoskeletal Disorders ◽

10.1186/1471-2474-15-114 ◽

2014 ◽

Vol 15 (1) ◽

Cited By ~ 41

Author(s):

Jianzhong Hu ◽

Yongchun Zhou ◽

Lihua Huang ◽

Jun Liu ◽

Hongbin Lu

Keyword(s):

Calcium Phosphate ◽

Biphasic Calcium Phosphate ◽

Hydroxyapatite Coating ◽

Calcium Phosphate Ceramics ◽

Porous Biphasic Calcium Phosphate

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Effects of Combined Magnetic Fields Treatment and Nano-Hydroxyapatite Coating on Porous Biphasic Calcium Phosphate Bone Graft in Rabbit Spinal Fusion Model

Spine ◽

10.1097/brs.0000000000002463 ◽

2018 ◽

Vol 43 (11) ◽

pp. E625-E633 ◽

Cited By ~ 2

Author(s):

Xianglong Zhuo ◽

Chentian Li ◽

Bing Li ◽

Zhaoyang Li ◽

Hongbin Lv ◽

...

Keyword(s):

Calcium Phosphate ◽

Magnetic Fields ◽

Bone Graft ◽

Spinal Fusion ◽

Biphasic Calcium Phosphate ◽

Hydroxyapatite Coating ◽

Fusion Model ◽

Combined Magnetic Fields ◽

Porous Biphasic Calcium Phosphate

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Mineralization of Chitosan via Alternate Soaking

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.353-358.2195 ◽

2007 ◽

Vol 353-358 ◽

pp. 2195-2198

Author(s):

Bao Qiang Li ◽

Ya Ping Guo ◽

Ke Huang ◽

De Chang Jia ◽

Yu Zhou ◽

...

Keyword(s):

Aqueous Solution ◽

Calcium Phosphate ◽

Acid Solution ◽

Amorphous Calcium Phosphate ◽

Ambient Condition ◽

Hydroxyapatite Coating ◽

Ageing Process ◽

Gradient Structure ◽

Chitosan Hydrogel ◽

Short Period

Hydroxyapatite coating was prepared by alternate soaking strategy in short period time and ambient condition. According to the pH near equality between chitosan acidic acid solution and H2PO4 - aqueous solution, we proposed to choose H2PO4 - as one of hydroxyapatite precursor instead of traditional candidate (HPO4 2-). The properties of chitosan hydrogel containing plenty of water provide enough spaces for hydroxyapatite precursor to diffuse into framework spontaneously. XRD, FTIR and SEM were used to characterize the component and microstructure of mineralized chitosan. The ageing process helps to transfer amorphous calcium phosphate in chitosan framework into hydroxyapatite. The hydroxyapatite coating is gradient structure according to the result of SEM.

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