Rapid Biomimetic Coating of Biocompatible Calcium Phosphate on Titanium: Influence of Pretreated NaOH Concentration and Cleaning Method

2015 ◽  
Vol 1119 ◽  
pp. 444-448 ◽  
Author(s):  
Faungchat Thammarakcharoen ◽  
Nattapat Hobang ◽  
Jintamai Suwanprateeb
Keyword(s):  
Calcium Phosphate ◽  
Sodium Hydroxide ◽  
Weight Change ◽  
Octacalcium Phosphate ◽  
Coating Process ◽  
Cleaning Method ◽  
Gel Layer ◽  
Biomimetic Coating ◽  
Coating Formation ◽  
Cleaning Methods

In this study, the influence of employing three different sodium hydroxide (NaOH) pretreatment concentration (1, 3 and 5M) and two cleaning methods (Ultrasonic or Rinse) used in rapid biomimetic coating process on phase composition, function groups, thickness, amount and microstructure of the resulted coating was carried out. Regardless of process parameters, x-ray diffraction and Fourier transform infrared spectroscopy revealed that the all coating mainly comprised octacalcium phosphate and hydroxyapatite as main phases while the microstructure similarly consisted of sharp and interconnected plate-like calcium phosphate (CaP) crystals vertically grown on the surface of titanium. However, the change in sodium hydroxide concentration in pretreatment step and cleaning method influenced the weight change after pretreatment, coating continuity and uniformity, but not the weight change after coating. This could be related to amount of the amorphous alkali gel layer formed during pretreatment step which influenced the rate of coating formation in rapid biomimetic coating process.

Rapid Biomimetic Coating of Calcium Phosphate on Titanium: Effect of Soaking Time, Temperature and Solution Refreshing

2016 ◽  
Vol 690 ◽  
pp. 81-86 ◽  
Author(s):  
Faungchat Thammarakcharoen ◽  
Jintamai Suwanprateeb
Keyword(s):  
Crystal Structure ◽  
Phase Composition ◽  
Calcium Phosphate ◽  
Octacalcium Phosphate ◽  
Solution Temperature ◽  
Phosphate Solution ◽  
Coating Process ◽  
Soaking Time ◽  
Biomimetic Coating ◽  
The Difference

The influence of employing three different solution temperatures (23, 37 and 50 °C), three soaking times (2, 4 and 6 h) and two solution refreshing methods (Refreshed or Non-refreshed) in rapid biomimetic coating process on phase composition, functional groups, coating content and microstructure of the resulted coating was studied. Increasing soaking times and temperature increased the coating content in all cases regardless of the use of refreshed or non-refreshed accelerated calcium phosphate solution. The use of non-refreshed solution resulted in the lower rate of coating than that of refreshed solution at all coating temperatures. However, all coatings similarly comprised octacalcium phosphate and hydroxyapatite as main phases and the microstructure consisted of sharp and interconnected plate-like crystals vertically grown on the surface of titanium. However, two types of crystal structure were produced. Low solution temperature resulted in isolated spheroids while uniform and distributed crystal structure was produced by using high solution temperature. This could be related to the difference in nucleation and precipitation rate formed in rapid biomimetic coating process as a result of the interplay between temperature and ionic strength of the solutions.

Effect of Process Parameters on Biomimetic Deposition of Calcium Phosphate on 3D Printed Hydroxyapatite

2017 ◽  
Vol 751 ◽  
pp. 599-604 ◽  
Author(s):  
Faungchat Thammarakcharoen ◽  
Jintamai Suwanprateeb
Keyword(s):  
Calcium Phosphate ◽  
Process Parameters ◽  
Weight Change ◽  
Three Dimensional ◽  
Octacalcium Phosphate ◽  
Solution Temperature ◽  
Factors Influencing ◽  
3D Printed ◽  
Biomimetic Deposition

Factors influencing calcium phosphate deposition on three dimensional printed hydroxyapatite (3D printed HA) by biomimetic process including soaking times (2, 4 and 6 hrs), solution temperatures (23, 37 and 50 °C) and solution refreshment (refreshed and non-refreshed) were studied. It was found that the weight change of the samples increased with increasing soaking times at all temperatures regardless of solution refreshment. Using refreshed solution resulted in greater increase in weight change than using non-refreshed solution. In the case of solution temperature, two opposite trends were observed depending on the solution refreshment. Increasing solution temperatures in non-refreshed solution exhibited a decrease in the weight change whereas the increase in the weight change was observed when using refreshed solution. This could be related to the competition between the dissolution of 3D printed HA and the deposition of new calcium phosphate crystals during biomimetic process. Octacalcium phosphate and HA were found to be the main phases of biomimetically deposited 3D printed HA.

scholarly journals Microwave-Assisted Fabrication of Mesoporous Silica-Calcium Phosphate Composites for Dental Application

Polymers ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 53
Author(s):  
Adrian Szewczyk ◽  
Adrianna Skwira ◽  
Marta Ginter ◽  
Donata Tajer ◽  
Magdalena Prokopowicz
Keyword(s):  
Calcium Phosphate ◽  
Mesoporous Silica ◽  
Octacalcium Phosphate ◽  
Precipitation Method ◽  
X Ray Diffraction ◽  
Coating Solution ◽  
X Ray ◽  
Microwave Assisted ◽  
Calcium Orthophosphates ◽  
Different Types

Herein, the microwave-assisted wet precipitation method was used to obtain materials consisting of mesoporous silica (SBA-15) and calcium orthophosphates (CaP). Composites were prepared through immersion of mesoporous silica in different calcification coating solutions and then exposed to microwave radiation. The composites were characterized in terms of molecular structure, crystallinity, morphology, chemical composition, and mineralization potential by Fourier-transform infrared spectroscopy (FTIR), powder X-ray diffraction (XRD), and scanning electron microscopy equipped with energy-dispersive X-ray spectroscopy (SEM-EDX). The application of microwave irradiation resulted in the formation of different types of calcium orthophosphates such as calcium deficient hydroxyapatite (CDHA), octacalcium phosphate (OCP), and amorphous calcium phosphate (ACP) on the SBA-15 surface, depending on the type of coating solution. The composites for which the progressive formation of hydroxyapatite during incubation in simulated body fluid was observed were further used in the production of final pharmaceutical forms: membranes, granules, and pellets. All of the obtained pharmaceutical forms preserved mineralization properties.

A protocol to develop crack-free biomimetic coatings on Ti6Al4V substrates

2007 ◽  
Vol 22 (6) ◽  
pp. 1593-1600 ◽  
Author(s):  
Sahil Jalota ◽  
Sutapa Bhaduri ◽  
Sarit B. Bhaduri ◽  
A. Cuneyt Tas
Keyword(s):  
Water Treatment ◽  
Calcium Phosphate ◽  
Alkali Treatment ◽  
Sodium Titanate ◽  
Calcium Phosphate Coating ◽  
First Case ◽  
Phosphate Coatings ◽  
Biomimetic Coating ◽  
One Step ◽  
Calcium Phosphate Coatings

Biomimetic coating of titanium and related alloys with carbonated apatitic calcium phosphate is an important area of research in implantology. While this paper specifically refers to coating Ti6Al4V, the results are valid with other related alloys as well. One step in the protocol involves an intermediate alkali treatment of Ti6Al4V to form a sodium titanate layer on the alloy surface. This pretreatment enhances the formation of the coating from simulated body fluid (SBF) solutions. Many papers in the biomimetic coating literature demonstrate the presence of cracks in coatings, irrespective of the SBF compositions and placement of the substrates. The presence of cracks may result in degradation and delamination of coatings. To the best of our knowledge, this issue remains unresolved. Therefore, the aim of this study was: (i) to examine and understand the reasons for cracking and (ii) based on the results, to develop a protocol for producing crack-free apatitic calcium phosphate coatings on Ti6Al4V substrates. In this study, the authors focused their attention on the alkali treatment procedure and the final drying step. It is hypothesized that these two steps of the process affect the crack formation the most. In the first case, the surfaces of alkali-treated substrates were examined with/without water-soaking treatment before immersing in SBF. This water treatment modifies the sodium titanate surface layer. In the second case, two different drying techniques (after soaking in SBF) were used. In one procedure, the coated substrates were dried rapidly, and in the other they were dried slowly. It was observed that the water treatment, irrespective of the drying method, provides a surface, which on subsequent soaking in SBF forms a crack-free apatitic calcium phosphate coating. Based on these results, the authors suggest a protocol incorporating a water-soaking treatment after the alkali treatment and prior to the SBF soaking treatment to obtain crack-free coatings.

Osteoconductive Property of a Mechanical Mixture of Octacalcium Phosphate and Amorphous Calcium Phosphate

2014 ◽  
Vol 6 (24) ◽  
pp. 22602-22611 ◽  
Author(s):  
Kazuhito Kobayashi ◽  
Takahisa Anada ◽  
Takuto Handa ◽  
Naofumi Kanda ◽  
Mariko Yoshinari ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Octacalcium Phosphate ◽  
Mechanical Mixture ◽  
Osteoconductive Property

scholarly journals Phosphoserine Functionalized Cements Preserve Metastable Phases, and Reprecipitate Octacalcium Phosphate, Hydroxyapatite, Dicalcium Phosphate, and Amorphous Calcium Phosphate, during Degradation, In Vitro

2019 ◽  
Vol 10 (4) ◽  
pp. 54 ◽  
Author(s):  
Joseph Lazraq Bystrom ◽  
Michael Pujari-Palmer
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Octacalcium Phosphate ◽  
Ionic Concentration ◽  
Strong Adhesion ◽  
Acidic Conditions ◽  
Rapid Transformation ◽  
Comparable Mass

Phosphoserine modified cements (PMC) exhibit unique properties, including strong adhesion to tissues and biomaterials. While TTCP-PMCs remodel into bone in vivo, little is known regarding the bioactivity and physiochemical changes that occur during resorption. In the present study, changes in the mechanical strength and composition were evaluated for 28 days, for three formulations of αTCP based PMCs. PMCs were significantly stronger than unmodified cement (38–49 MPa vs. 10 MPa). Inclusion of wollastonite in PMCs appeared to accelerate the conversion to hydroxyapatite, coincident with slight decrease in strength. In non-wollastonite PMCs the initial compressive strength did not change after 28 days in PBS (p > 0.99). Dissolution/degradation of PMC was evaluated in acidic (pH 2.7, pH 4.0), and supersaturated fluids (simulated body fluid (SBF)). PMCs exhibited comparable mass loss (<15%) after 14 days, regardless of pH and ionic concentration. Electron microscopy, infrared spectroscopy, and X-ray analysis revealed that significant amounts of brushite, octacalcium phosphate, and hydroxyapatite reprecipitated, following dissolution in acidic conditions (pH 2.7), while amorphous calcium phosphate formed in SBF. In conclusion, PMC surfaces remodel into metastable precursors to hydroxyapatite, in both acidic and neutral environments. By tuning the composition of PMCs, durable strength in fluids, and rapid transformation can be obtained.

Bioactive Calcium Phosphate Coating on Sodium Hydroxide-Pretreated Titanium Substrate by Electrodeposition

2004 ◽  
Vol 87 (9) ◽  
pp. 1792-1794 ◽  
Author(s):  
Ji-Ho Park ◽  
Doug-Youn Lee ◽  
Keun-Taek Oh ◽  
Yong-Keun Lee ◽  
Kyoung-Nam Kim
Keyword(s):  
Calcium Phosphate ◽  
Sodium Hydroxide ◽  
Titanium Substrate ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating
Sign in / Sign up

Export Citation Format

Share Document