Research update of emergent gold nanoclusters: A reinforced approach towards evolution, synthesis mechanism and application

Talanta ◽  
2022 ◽  
pp. 123228
Author(s):  
Imran Mahmood Khan ◽  
Sobia Niazi ◽  
Lin Yue ◽  
Yin Zhang ◽  
Imran Pasha ◽  
...  
2021 ◽  
pp. 004051752198977
Author(s):  
Xin Zhang ◽  
Yuanyuan Dong ◽  
Gangzhong Liu ◽  
Guosheng Zhang ◽  
Jie Li ◽  
...  

Nanoclusters, with their ultrasmall sizes, have emerged as an indispensable tool in designing structural materials with a wide range of applications, but predicting the synthesis mechanism and structures remains challenging. This work delineates a synthesis mechanism of gold nanoclusters (AuNCs), which is realized by functionalizing a wool keratin (WK) and silk fibroin (SF) resilience network structure via self-assembly with controllable microstructure transformation. We synthesized such AuNCs by reducing the thiol groups of WK into WK@AuNCs and then entering the WF&SF resilience framework during the reconstruction, achieving WK@AuNCs/WK&SF with high fluorescence intensity for selective quenching of heavy metal Cu2+ ions. Further investigation indicated that α-helix and β-crystallites resulted in a soft–hard molecular segment denoted as WK&SF resilience network, which held and separated the WK@AuNCs into the nanocages. Owing to the synergism of these features, WK@AuNCs/WK&SF displayed superior fluorescence performances compared with WK@AuNCs.


1998 ◽  
Vol 78 (4) ◽  
pp. 385-396 ◽  
Author(s):  
V. Kasperovich, V. V. Kresin
Keyword(s):  

2019 ◽  
Vol 19 (8) ◽  
pp. 567-578 ◽  
Author(s):  
Marcus Vinicius Nora de Souza ◽  
Thais Cristina Mendonça Nogueira

Nowadays, tuberculosis (TB) is an important global public health problem, being responsible for millions of TB-related deaths worldwide. Due to the increased number of cases and resistance of Mycobacterium tuberculosis to all drugs used for the treatment of this disease, we desperately need new drugs and strategies that could reduce treatment time with fewer side effects, reduced cost and highly active drugs against resistant strains and latent disease. Considering that, 4H-1,3-benzothiazin-4-one is a promising class of antimycobacterial agents in special against TB-resistant strains being the aim of this review the discussion of different aspects of this chemical class such as synthesis, mechanism of action, medicinal chemistry and combination with other drugs.


2020 ◽  
Vol 94 (12) ◽  
pp. 2421-2427
Author(s):  
R. Kh. Saryeva ◽  
N. S. Kozhevnikova ◽  
L. N. Maskaeva ◽  
V. F. Markov ◽  
V. I. Voronin ◽  
...  

Author(s):  
Lu Zhang ◽  
Benchao Zheng ◽  
Rui Guo ◽  
Ying Miao ◽  
Biao Li

The human sodium iodide symporter (hNIS) can be linked to the downstream of radiation-sensitive early growth response protein1 (Egr1) promoter, and activated by the Egr1 following 131I treatment. However, the...


2021 ◽  
Author(s):  
Xu Liu ◽  
Guo Yao ◽  
Xinglian Cheng ◽  
Jiayu Xu ◽  
Xiao Cai ◽  
...  

With atomically precise gold nanoclusters acting as a starting unit, substituting one or more gold atoms of the nanocluster with other metals has become an effective strategy to create metal...


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