Accuracy of magnetic resonance venography in diagnosing cerebral venous sinus thrombosis

2018 ◽  
Vol 167 ◽  
pp. 64-73 ◽  
Author(s):  
Liansheng Gao ◽  
Weilin Xu ◽  
Tao Li ◽  
Xiaobo Yu ◽  
Shenglong Cao ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Magnetic Resonance Venography ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis

Safety and Validity of Mechanical Thrombectomy and Thrombolysis on Severe Cerebral Venous Sinus Thrombosis

Neurosurgery ◽  
2013 ◽  
Vol 72 (5) ◽  
pp. 730-738 ◽  
Author(s):  
Guangwen Li ◽  
Xianwei Zeng ◽  
Mohammed Hussain ◽  
Ran Meng ◽  
Yi Liu ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Treatment Modality ◽  
Mechanical Thrombectomy ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Magnetic Resonance Venography ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Digital Subtract Angiography

Abstract BACKGROUND: Although the majority of patients with cerebral venous sinus thrombosis (CVST) obtain an optimistic clinical outcome after heparin or warfarin treatment, there remains a subgroup of patients who do not respond to conventional anticoagulation treatment. These patients, especially younger people, as documented by hospital-based studies, have a high morbidity and mortality rate. OBJECTIVE: To verify the safety and efficacy of a dual mechanical thrombectomy with thrombolysis treatment modality option in patients with severe CVST. METHODS: Fifty-two patients diagnosed with CVST were enrolled and treated with mechanical thrombectomy combined with thrombolysis. Patients underwent urokinase 100 to 1500 × 103 IU intravenous sinus injection via a jugular catheter after confirming diagnoses of CVST by using either magnetic resonance imaging/magnetic resonance venography or digital subtract angiography. Information obtained on the patients included recanalization status of venous sinuses as evaluated by magnetic resonance venography or digital subtract angiography at admission, during operation, and at 3- and 6-month follow-up after treatment. RESULTS: The percentage of patients that showed complete and partial recanalization were 87% and 6%, respectively, after mechanical thrombectomy combined with thrombolysis treatment; 8% of the patients showed no recanalization. The modified Rankin Scale scores were 1.0 ± 0.9, 0.85 ± 0.63, and 0.37 ± 0.53 for discharge, and 3- and 6-month follow-up, respectively. A total of 6 patients died despite receiving aggressive treatment. No cases of relapse occurred after 3 to 6 months of follow-up. CONCLUSION: Thrombectomy combined with thrombolysis is a safe and valid treatment modality to use in severe CVST cases or in intractable patients that have shown no adequate response to antithrombotic drugs.

Papilloedema secondary to venous sinus thrombosis following glomus jugulare tumour surgery

2009 ◽  
Vol 123 (12) ◽  
pp. 1393-1395 ◽  
Author(s):  
S Izadi ◽  
P D Karkos ◽  
R Krishnan ◽  
J Hsuan ◽  
T H J Lesser
Keyword(s):  
Case Report ◽  
Magnetic Resonance ◽  
World Literature ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Magnetic Resonance Venography ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Glomus Jugulare ◽  
Glomus Jugulare Tumour

AbstractObjective:We present a case of a patient who had undergone embolisation and resection of a left glomus jugulare tumour, who presented three weeks post-operatively with magnetic resonance venography confirmed symptomatic cerebral venous sinus thrombosis.Method:We present a case report and a review of the world literature concerning glomus jugulare tumours and cerebral venous sinus thrombosis.Case report:A 42-year-old man presented with blurred vision and reduced Snellen visual acuity just three weeks after glomus jugulare tumour surgery. Fundoscopy revealed bilateral haemorrhagic optic disc oedema. Urgent magnetic resonance venography confirmed a left lateral venous sinus thrombosis. It was felt that this was responsible for inadequate cerebrospinal fluid drainage, resulting in raised intracranial pressure and papilloedema.Conclusion:To the authors' knowledge, this is the first account of a magnetic resonance venography confirmed venous sinus thrombosis and secondary papilloedema following glomus jugulare tumour surgery. Patients undergoing surgery involving resection or manipulation of the internal jugular vein may be at higher risk of developing thrombosis superior to the level of resection, and magnetic resonance venography ought to be considered an important diagnostic adjunct.

scholarly journals Uncontrolled seizures resulting from cerebral venous sinus thrombosis complicating neurobrucellosis

2013 ◽  
Vol 04 (03) ◽  
pp. 313-316 ◽  
Author(s):  
Fardin Faraji ◽  
Farshid Didgar ◽  
Afsoon Talaie-Zanjani ◽  
Abolfazl Mohammadbeigi
Keyword(s):  
Magnetic Resonance ◽  
Sinus Thrombosis ◽  
Good Condition ◽  
Complex Partial Seizure ◽  
Transverse Sinus ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Laboratory Assessment ◽  
Venous Sinus Thrombosis ◽  
High Doses

ABSTRACTCerebral venous sinus thrombosis is a rare form of stroke caused by thrombosis in venous sinuses of the brain. In this study, we reported on a patient with venous sinus thrombosis and brucellosis who presented with uncontrolled seizure despite being treated with anti-epileptic drugs at high doses. The case was a 33-year-old woman with a history of controlled complex partial seizure who presented with headache, asthenia, and uncontrolled seizure for one month. She was febrile and a brain CT scan indicated hemorrhagic focus in the left posterior parietal and the temporal lobe. Magnetic resonance imaging and magnetic resonance venography also proved venous sinus thrombosis in the left transverse sinus. Besides [In addition], a laboratory assessment confirmed brucellosis. Following the treatment with anti-coagulant, anti-brucellosis, and anti-epileptic agents, the patient was discharged in good condition with medical orders. Clinical suspicion and accurate evaluation of a patient′s history is the most important clue in diagnosis and treatment of brucellosis and cerebral venous sinus thrombosis, especially in uncontrolled seizure in patients who had previously been under control.

scholarly journals Postpartum Seizures: Cerebral Venous Sinus Thrombosis, Case Report

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Ahmed AAH ◽  
Keyword(s):  
Magnetic Resonance ◽  
Sinus Thrombosis ◽  
Past History ◽  
Good Condition ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
High Grade Fever ◽  
Venous Sinus Thrombosis ◽  
Magnetic Resonance Imaging Mri ◽  
The Right

Cerebral venous sinus thrombosis is of rarity during pregnancy, and it is included in the differential diagnosis of a woman presenting with seizures during pregnancy and puerperium. Here we report a case of young lady who developed Cerebral Venous Sinus Thrombosis (CVST) 6 days after delivery, presented with a chief complain of loss of consciousness and high grade fever with recent past history of severe occipital headache and generalized convulsions, which progressed into left sided weakness. Magnetic Resonance Imaging (MRI) / Magnetic Resonance Venography (MRV) demonstrated filling defects at the right transverse and sigmoid sinuses. The patient was started on Enoxaparin and warfarin. The patient kept on improving gradually and was discharged after 24 days in a good condition.

Cerebral venous sinus thrombosis

2014 ◽  
Vol 30 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Marcin Hartel ◽  
Ewa Kluczewska ◽  
Eliza Gancarczyk-Urlik ◽  
Krystyna Pierzchała ◽  
Karolina Bień ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Early Stage ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Resonance Imaging ◽  
Venous Sinus Thrombosis ◽  
Magnetic Resonance Imaging Mri

Diagnostic imaging in cerebral venous sinus thrombosis poses difficulties due to the relatively rare incidence of this pathology and its usually inconclusive clinical and radiological symptoms. The preliminary examination is usually performed using computed tomography, whereas magnetic resonance imaging (MRI) provides better visualisation of the lesion. Computed tomography and magnetic resonance imaging angiography enable the characterisation of the blood flow in the pathologically affected vessels in more detail. Familiarity with the anatomic variations of the venous system and with the advantages and limitations of computed tomography/magnetic resonance imaging enables faster diagnosis of the pathology. This is significant for treatment, which, in many cases, can be efficient only if introduced at a sufficiently early stage.

scholarly journals Cerebral Venous Sinus Thrombosis following Diagnostic Curettage in a Patient with Uterine Fibroid

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Xiao-Qun Zhu ◽  
Li Cao
Keyword(s):  
Magnetic Resonance ◽  
Uterine Fibroid ◽  
Sinus Thrombosis ◽  
Brain Magnetic Resonance Imaging ◽  
Diagnostic Technique ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Deficiency Anemia ◽  
Venous Sinus Thrombosis ◽  
Convulsive Seizures

Cerebral venous sinus thrombosis (CVST) is a relatively rare cerebrovascular disease, of which the risk has been documented in patients with numerous conditions. However, CVST has never been previously described in association with the use of a diagnostic curettage in patient with uterine fibroid. Herein, we described a 43-year-old woman who presented with recurrent convulsive seizures and severe and progressive headache 1 day after a diagnostic curettage of the uterus, which was confirmed to be uterine fibroid pathologically later, and her condition subsequently progressed to confusion. Brain magnetic resonance imaging (MRI) revealed an acute extensive thrombosis of the left transverse and sigmoid sinus and the ipsilateral cerebellum infarction. Evaluation for primary thrombophilia revealed that an iron deficiency anemia (IDA) due to the fibroid bleeding induced menorrhagia together with a diagnostic curettage might be the sole hypercoagulable risk factor identified. Treatment with anticoagulation led to full recovery of her symptoms and recanalization of the thrombosis was proven on magnetic resonance venography (MRV) 2 months later. We suggest that CVST should be recognized as a potential complication related to this diagnostic technique, especially in patient with IDA. The early diagnosis and timely treatment would be of significance in improving the prognosis of this potentially lethal condition.

scholarly journals HUBUNGAN KADAR D-DIMER DENGAN AWITAN GEJALA DAN LAMA PERAWATAN PADA PENDERITA CEREBRAL VENOUS SINUS THROMBOSIS DI RSUP DR HASAN SADIKIN BANDUNG

2020 ◽  
Vol 37 (2) ◽  
Author(s):  
Lisda Amalia ◽  
Adnin Nugroho
Keyword(s):  
Computed Tomography ◽  
Magnetic Resonance ◽  
Magnetic Resonance Angiography ◽  
Length Of Stay ◽  
Computed Tomography Angiography ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
D Dimer

CORRELATION BETWEEN D-DIMER LEVEL WITH ONSET OF SYMPTOMS AND LENGTH OF STAY IN CEREBRAL VENOUS SINUS THROMBOSIS PATIENTS AT HASAN SADIKIN HOSPITAL BANDUNGABSTRACTIntroduction:Cerebral venous sinus thrombosis (CVST)is one of a cerebrovascular disease with a diverse and elusive clinical presentation. Diagnosis is often challenging due to limitation in diagnostic tools.Coagulation disorder is one of the risk factor for CVST that can be seen from D-dimer level which tends to increase in CVST patients.Aim: This study aims to determine the D-dimer leveland its correlation with onset of symptoms and length of stay in CVST patients at Hasan Sadikin Hospital, Bandung.Methods: This is a cross-sectional study. The inclusion criteria were patients at Hasan Sadikin Hospital, Bandung diagnosed as CVST, confirmed by digital subtraction angiography (DSA) or computed tomography angiography (CTA) or magnetic resonance angiography (MRA) and had blood coagulation profile in the period of January 2018-May 2019. Exclusion criteria were patients with infection or sepsis. Data were collected from the patient’s medical record. Statistical value was calculated with Spearman rank test, p value<0.05 was considered significant.Results: Forty CVST patients met the criteria. CVST mostly occurred in women (80%), the mean age were 40,75 years, and had headache as primary symptom (70%). Twenty-eight(70%) patients had increased level of D-dimer. D-dimer level had negative correlation with onset of symptoms (r=-0.319, p=0.045). However, it hadassociationwith length of stay (p=0.012).Discussion: D-dimer level in CVST patients tends to increase above normal value. D-dimer level have correlation with onset of symptoms and length of stay in CVST patients.Keywords:Cerebral venous sinus thrombosis, D-dimer level, length of stay, onset of symptomsABSTRAK                          Pendahuluan: Trombosis pada vena serebral (cerebral venous sinus thrombosis/CVST) merupakan salah satu diagnosis dalam bidang cerebrovaskular yang sulit ditegakkan karena keterbatasan alat untuk diagnosis pasti. Salah satu faktor risiko terjadinya CVST adalah kelainan koagulasi yang dapat dilihat dari kadar D-dimer yang cenderung meningkat.Tujuan: Mengetahui gambaran profil D-dimer pada penderita CVST dan hubungannya dengan awitan gejala dan lama perawatan di RSUP Dr. Hasan Sadikin, Bandung.Metode: Penelitian ini merupakan penelitian potong lintang. Kriteria inklusi yaitu pasien yang terdiagnosis CVST melalui pemeriksaan digital substraction angiography (DSA) atau computed tomography angiography (CTA) atau magnetic resonance angiography (MRA) dan memiliki profil koagulasi serta dirawat di RSUP Dr. Hasan Sadikin, Bandung pada periode Januari 2018–Mei 2019. Kriteria eksklusi yaitu pasien yang disertai infeksi atau sepsis. Data diambil dari penelusuran rekam medis pasien dan dianalisis menggunakan korelasi Spearman. Signifikansi dinyatakan bila p<0,05.Hasil: Terdapat 40 pasien CVST yang memenuhi kriteria inklusi. CVST mayoritas terjadi pada perempuan (80%), rerata usia 40,75 tahun dengan keluhan utama tersering adalah nyeri kepala (70%). Terdapat 28 pasien memiliki kadar D-dimer yang meningkat (70%). Berdasarkan analisis, kadar D-dimer memiliki hubungan negatif dengan awitan gejala pasien (r=0,319, p= 0,045). Kadar D-dimer juga memiliki hubungan dengan lama perawatan (p=0,012).Diskusi: Kadar D-dimer pada penderita CVST cenderung lebih tinggi dari nilai normal. Kadar D-dimer memiliki hubungan dengan awitan gejala dan lama perawatan pasien CVST di rumah sakit.Kata kunci: Awitan gejala, cerebral venous sinus thrombosis, kadar D-dimer, lama perawatan

scholarly journals Cerebral Venous Sinus Thrombosis- A Study of 4 Cases

2017 ◽  
Vol 33 (1) ◽  
pp. 30-33
Author(s):  
Abdul Kader Sheikh ◽  
Rama Biswas ◽  
Anindita Roy ◽  
Sadiqa Tuqan ◽  
Mallika Sarker ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Clinical Presentation ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Focal Neurological Deficit ◽  
Venous Sinus Thrombosis ◽  
Aged Woman ◽  
Supportive Management ◽  
Variable Presentation

Cerebral venous sinus thrombosis is an uncommon but important cause of stroke, especially in young-aged woman. Clinical presentation is variable, usually in the form of focal neurological deficit, seizure, headache and other features of raised intracranial pressure, leading to misdiagnosis or delay in treatment. Here we report 4 cases of venous sinus thrombosis with variable presentation. Diagnosis is confirmed by neuroimaging including magnetic resonance imaging with magnetic resonance venography of brain. Treatment consists of anticoagulation along with supportive management. Bangladesh Journal of Neuroscience 2017; Vol.  33 (1): 30-33

Visual loss after long-haul flight

2020 ◽  
pp. 112067212096549
Author(s):  
Nurliyana Ain Abdul Ghani ◽  
Azlindarita Aisyah Binti Mohd Abdullah ◽  
Shamsiah Abdul Hamid ◽  
Muhamad Yazli Yuhana ◽  
Norlina Ramli
Keyword(s):  
Magnetic Resonance ◽  
Anticoagulant Therapy ◽  
Visual Loss ◽  
Sinus Thrombosis ◽  
Complete Recovery ◽  
Transverse Sinus ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Medical Illness ◽  
Venous Sinus Thrombosis

Background: Deep cerebral venous sinus thrombosis is a reversible yet potentially serious thromboembolic event. A number of reports suggest a relationship between long-haul flights and thromboembolic events, mainly deep venous thrombosis (DVT) and pulmonary embolism (PE). It is rarely reported to cause deep cerebral venous sinus thrombosis. We report a case of a bilateral papilledema after long-haul flight secondary to deep cerebral venous sinus thrombosis with subsequent complete recovery post corticosteroid and anticoagulant therapy. Case: A case of a 21-year-old woman with no known medical illness who presented with gradual painless bilateral visual loss is described. She had a history of travelling on a long-haul flight 3 weeks prior to presentation. Examination showed presence of bilateral papilloedema, no vitritis, choroiditis and retinitis. Blood investigations showed raised international normalised ratio (INR). Otherwise, workup for infectious causes of optic disc swelling, connective tissue disease screening were normal. Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) of the brain showed loss of flow signal in the right transverse sinus and the left sigmoid sinus. Blood workup for preexisting hypercoagulable state was normal. She was diagnosed with deep cerebral venous sinus thrombosis and showed complete recovery with oral corticosteroid and anticoagulant therapy. Conclusion: Deep cerebral venous sinus thrombosis is a potentially serious consequence of long-haul flights. A high index of suspicion along with radiological techniques is needed for early detection and initiation of anticoagulation for this reversible condition.

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