Panton-Valentine leukocidin producing Staphylococcus aureus as a cause for re-current, contagious pyoderma in young, healthy travellers returned from a tropical country: A new worldwide public health problem?

2007 ◽  
Vol 5 (6) ◽  
pp. 402-403
Author(s):  
R. Schleucher ◽  
M. Gaessler ◽  
J. Knobloch
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Health Problem ◽  
Public Health Problem ◽  
Tropical Country ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

scholarly journals First cases of infections caused by Panton-Valentine leukocidin positive community-acquired methicillin-resistant Staphylococcus aureus in Bulgaria

2007 ◽  
Vol 12 (26) ◽  
Author(s):  
D Nashev ◽  
L Bizeva ◽  
K Toshkova
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Health Problem ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Methicillin Resistant ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

Infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) have emerged as a major public health problem worldwide.

scholarly journals The first isolation of Panton-Valentine leukocidin (PVL) positive community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in Russia

2007 ◽  
Vol 12 (11) ◽  
Author(s):  
T Baranovich ◽  
V Potapov ◽  
T Yamamoto
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Public Health Problem ◽  
The United States ◽  
Important Public Health Problem ◽  
Methicillin Resistant ◽  
Important Public Health ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

Since the first report of pediatric deaths in 1997-1999 in the United States, community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has become an increasingly important public health problem worldwide.

scholarly journals Community-Associated Methicillin-ResistantStaphylococcus aureusLacking PVL, as a Cause of Severe Invasive Infection Treated with Linezolid

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Catarina Gouveia ◽  
Alexandra Gavino ◽  
Ons Bouchami ◽  
Maria Miragaia ◽  
Luis Varandas ◽  
...  
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Synovial Fluid ◽  
Public Health Problem ◽  
Invasive Infection ◽  
Limited Information ◽  
Invasive Infections ◽  
Sport Athlete ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

Community-associated methicillin-resistantStaphylococcus aureus(CA-MRSA) is an emerging public health problem worldwide. Severe invasive infections have been described, mostly associated with the presence of Panton-Valentine leukocidin (PVL). In Portugal limited information exists regarding CA-MRSA infections. In this study we describe the case of a previously healthy 12-year-old female, sport athlete, who presented to the hospital with acetabulofemoral septic arthritis, myositis, fasciitis, acetabulum osteomyelitis, and pneumonia. The MRSA isolated from blood and synovial fluid was PVL negative and staphylococcal enterotoxin type P (SEP) and type L (SEL) positive, with a vancomycin MIC of 1.0 mg/L and resistant to clindamycin and ciprofloxacin. The patient was submitted to multiple surgical drainages and started on vancomycin, rifampicin, and gentamycin. Due to persistence of fever and no microbiological clearance, linezolid was started with improvement. This is one of the few reported cases of severe invasive infection caused by CA-MRSA in Portugal, which was successfully treated with linezolid. In spite of the severity of infection, the MRSA isolate did not produce PVL.

scholarly journals Distribution of Toxinogenic Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus from Different Ecological Niches in Algeria

Toxins ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 500 ◽  
Author(s):  
Assia Mairi ◽  
Abdelaziz Touati ◽  
Alix Pantel ◽  
Karima Zenati ◽  
Alex Yahiaoui Martinez ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Staphylococcus Aureus ◽  
Health Problem ◽  
Ecological Niches ◽  
Wild Animals ◽  
Methicillin Resistant ◽  
Human Infections ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin ◽  
Permanent Reservoir

The diffusion of Panton–Valentine leukocidin (PVL)–positive methicillin-resistant S. aureus (MRSA) is a health problem in Algeria. The objectives of the study were to investigate the global distribution of methicillin-susceptible S. aureus (MSSA) and MRSA isolates in different ecological niches in this country. In total, 2246 samples were collected from humans, livestock, wild animals, pets, food products and the aquatic environment, from 12 Algerian provinces. A total of 312 S. aureus were detected from 2446 samples (12.7%) in the screened niches. We observed the emergence of toxinogenic S. aureus representing 41% of the isolates. Among them, we noted the diffusion of ST80-IV CA-MRSA PVL + strains isolated in human, animals, and food and genetic diversity of MSSA PVL + isolates. This study suggests an alarming dissemination of MRSA-ST80 PVL + in both human and extra-human sources in Algeria. Moreover, MSSA may become a permanent reservoir of the PVL genes necessary for human infections.

Panton-Valentine Leukocidin Staphylococcus Aureus (PVL-SA) – an uninvited stowaway aboard a Royal Navy submarine

2013 ◽  
Vol 99 (1) ◽  
pp. 3-8
Author(s):  
SJN Bourn ◽  
G Evans ◽  
MK O’Shea
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Soft Tissue ◽  
Virulence Factor ◽  
Invasive Disease ◽  
Soft Tissue Infections ◽  
Royal Navy ◽  
Military Populations ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

AbstractThe toxin Panton-Valentine Leukocidin (PVL) is a virulence factor produced by some strains of Staphylococcus aureus (S. aureus, SA) that destroys leucocytes. PVL-SA predominantly results in skin and soft tissue infections (SSTIs) but may also cause invasive disease, including necrotising pneumonia, which may affect healthy young individuals and has a high mortality. We describe a case of PVL-SA in a submariner who presented at sea and which resulted in a requirement to both alter the submarine’s programme and undertake population screening. The case highlights many important issues pertinent to military populations including clinical and public health considerations.

scholarly journals S. aureus and MRSA Nasal Carriage in Dental Students: A Comprehensive Approach

2021 ◽  
Vol 5 (1) ◽  
pp. 34
Author(s):  
Patrícia Cavaco-Silva ◽  
Maria Mole ◽  
Beatriz Meliço ◽  
Helena Barroso
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
Infection Control ◽  
Health Problem ◽  
Sccmec Type ◽  
Public Health Problem ◽  
Nasal Carriage ◽  
Dental Students ◽  
Clinical Pathogens ◽  
Mrsa Colonization

Staphylococcus aureus and MRSA are important clinical pathogens representing a serious public health problem. This study aimed to determine the prevalence of S. aureus and methicillin-resistant S. aureus (MRSA) nasal carriage among dental students, identify the factors that influence this carriage, and characterize MRSA. A prevalence of S. aureus and MRSA carriage of 25.2% and 0.86% was estimated, respectively, and SCCmec Type VI, was identified in all isolated MRSA. The low MRSA colonization rate can reflect good infection control practices followed by students.

scholarly journals Introduction of surveillance of infections with Staphylococcus aureus containing the Panton-Valentine Leukocidin gene in the Netherlands

2003 ◽  
Vol 7 (16) ◽  
Author(s):  
E Tiemersma ◽  
W J B Wannet ◽  
E. L.M. op de Coul ◽  
A J de Neeling ◽  
M J W van de Laar
Keyword(s):  
Public Health ◽  
Staphylococcus Aureus ◽  
The Netherlands ◽  
Skin Infections ◽  
Epidemic Strain ◽  
Mrsa Strains ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin

The National Institute of Public Health and the Environment (RIVM) in the Netherlands has begun surveillance of Staphylococcus aureus (MRSA) strains with the Panton-Valentine Leukocidin (PVL) gene in the Netherlands. This PVL gene is known to produce a potent toxin causing severe skin infections and necrotising pneumonia in both immunocompromised and immunocompetent individuals. About 60% of PVL positive isolates in the Netherlands belonged to ‘cluster 28’, which is an epidemic strain in the European mainland, but which has not yet caused large outbreaks in the Netherlands.

scholarly journals Problem of Malaria Infection

2017 ◽  
Vol 7 (2) ◽  
Author(s):  
Soebaktiningsih .
Keyword(s):  
Public Health ◽  
Plasmodium Falciparum ◽  
Combination Treatment ◽  
Health Problem ◽  
Molecular Basis ◽  
Malaria Infection ◽  
Public Health Problem ◽  
Malaria In Pregnancy ◽  
Tropical Country ◽  
In Pregnancy

Malaria is still Public Health Problem in tropical country. Failure of Mefloquine – Artesunate combination treatment of uncomplicated Plasmodium falciparum beginning to fail is due to the delayed clearance times and elevated Artesunate IC50, suggest thatArtesunate resistance may be emerging on background of Mefloquine resistance ( Rogers et al 2009). Pathogenesis of malaria in pregnancy is related to the ability of Plasmodium falciparum intra erythrocyte to sequester in the placenta. Study to understand the molecular basis of susceptibility to malaria in pregnancy has been advanced through the discovery of Chondroitin Sulfat A (CSA) molecule that support the accumulation of infected erythrocytes (IE) by Plasmodium falciparum in the placenta

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