Exploration study on serum metabolic profiles of Chinese male patients with artificial stone silicosis, silicosis, and coal worker's pneumoconiosis

2021 ◽  
Author(s):  
Huanqiang Wang ◽  
Siyun Zhou ◽  
Yi Liu ◽  
Yihan Yu ◽  
Sha Xu ◽  
...  
Keyword(s):  
Metabolic Profiles ◽  
Male Patients ◽  
Artificial Stone ◽  
Chinese Male

scholarly journals A three-microRNA signature for lung squamous cell carcinoma diagnosis in Chinese male patients

Oncotarget ◽  
2017 ◽  
Vol 8 (49) ◽  
pp. 86897-86907 ◽  
Author(s):  
Lan Zhang ◽  
Xia Shan ◽  
Jun Wang ◽  
Jun Zhu ◽  
Zebo Huang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Male Patients ◽  
Chinese Male

scholarly journals CARD8 rs2043211 Polymorphism is Associated with Gout in a Chinese Male Population

2015 ◽  
Vol 35 (4) ◽  
pp. 1394-1400 ◽  
Author(s):  
Ying Chen ◽  
Xianfeng Ren ◽  
Changgui Li ◽  
Shichao Xing ◽  
Zhengju Fu ◽  
...  
Keyword(s):  
Renal Calculus ◽  
Genotype Distribution ◽  
Male Population ◽  
Chinese Han ◽  
Increased Risk ◽  
Phenotype Analysis ◽  
Obvious Association ◽  
Male Patients ◽  
Chinese Male ◽  
Control Study

Background &Aim: Previous studies have suggested genetic factors are involved in the development of gout. We performed a case-control study to investigate the genetic association between CARD8 rs2043211 polymorphism and gout. Methods: A total of 396 male patients with gout and 403 age- and sex- matched healthy controls were included in this study. Genotyping was performed using TaqMan SNP Genotyping Assays. An association analysis was carried out using the χ2 test. The genotype-phenotype analysis was also conducted. Results: The genotype distribution of CARD8 rs2043211 polymorphism confirmed to HWE in the controls (P = 0.27). There was an obvious difference in the genotype distribution of CARD8 rs2043211 polymorphism between cases and controls (P = 0.017). In addition, there was an obvious association between CARD8 rs2043211 polymorphism and gout under the recessive comparison model (AA vs. TT/TA: OR = 0.65, 95%CI 0.47-0.88, P = 0.006). Patients carrying genotype TT of CARD8 rs2043211 polymorphism had higher triglycerides levels compared to those carrying the AA genotype (2.77±2.08 mmol/L vs. 2.07±1.15 mmol/L, P = 0.01). Patients with the TT genotype also had significantly higher systolic blood pressure compared with those with the AA genotype (142.11±21.10 mmHg vs. 135.38±14.66 mmHg, P = 0.03). Patients carrying TT genotype also had an increased risk of renal calculus compared with those carrying the AA genotype. Conclusion: CARD8 rs2043211 polymorphism is significantly associated with susceptibility to gout in Chinese Han males.

Facial emotion recognition and alexithymia in Chinese male patients with deficit schizophrenia

2016 ◽  
Vol 246 ◽  
pp. 353-359 ◽  
Author(s):  
Xiao Wei Tang ◽  
Miao Yu ◽  
Wei Wei Duan ◽  
Xiang Rong Zhang ◽  
Wei Wei Sha ◽  
...  
Keyword(s):  
Emotion Recognition ◽  
Facial Emotion Recognition ◽  
Facial Emotion ◽  
Deficit Schizophrenia ◽  
Male Patients ◽  
Chinese Male

scholarly journals Serum Glycerophospholipid Profile in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Xiaoyan Gai ◽  
Chenglin Guo ◽  
Linlin Zhang ◽  
Lijiao Zhang ◽  
Mairipaiti Abulikemu ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Acute Exacerbation ◽  
Chronic Obstructive ◽  
Blood Eosinophil ◽  
Metabolic Profiles ◽  
Obstructive Pulmonary Disease ◽  
Recovery Stage ◽  
Receiver Operating Characteristic Curves ◽  
Male Patients

Studies have shown that glycerophospholipids are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study adopted targeted metabolomic analysis to investigate the changes in serum glycerophospholipids in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and their differential expression in patients with different inflammatory subtypes. Patients with AECOPD admitted between January 2015 and December 2017 were enrolled, and their clinical data were collected. The patients’ gender, age, body mass index, and lung function were recorded. Routine blood and induced sputum tests were performed. Liquid chromatography-mass spectrometry was used to detect the serum glycerophospholipid metabolic profiles and to analyze the metabolic profile changes between the acute exacerbation and recovery stages as well as the differences between different inflammatory subtypes. A total of 58 patients were hospitalized for AECOPD, including 49 male patients with a mean age of 74.8 ± 10.0 years. In the metabolic profiles, the expression of lysophosphatidylcholine (LPC) 18:3, lysophosphatidylethanolamine (LPE) 16:1, and phosphatidylinositol (PI) 32:1 was significantly reduced in the acute exacerbation stage compared to the recovery stage (P < 0.05). The three glycerophospholipids were used to plot the receiver operating characteristic curves to predict the acute exacerbation/recovery stage, and the areas under the curves were all above 70%. There were no differential metabolites between the two groups of patients with blood eosinophil percentage (EOS%) ≥2% and <2% at exacerbation. The expression of LPC 18:3, LPE 16:1, and PI 32:1 was significantly reduced in the acute exacerbation stage compared to the recovery stage in the inflammatory subtype with blood EOS <2% (P < 0.05). Abnormalities in the metabolism of glycerophospholipids may be involved in the onset of AECOPD, especially in the non-eosinophilic subtype.

scholarly journals Changes in therapeutic strategies in Chinese male patients with breast cancer: 40 years of experience in a single institute

The Breast ◽  
2010 ◽  
Vol 19 (6) ◽  
pp. 450-455 ◽  
Author(s):  
Fei-Fei Zhou ◽  
Liang-Ping Xia ◽  
Gui-Fang Guo ◽  
Xi Wang ◽  
Zhong-Yu Yuan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Therapeutic Strategies ◽  
Years Of Experience ◽  
Male Patients ◽  
Chinese Male
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