scholarly journals In vitro toxicity assessment of chitosan oligosaccharide coated iron oxide nanoparticles

2015 ◽  
Vol 2 ◽  
pp. 27-39 ◽  
Author(s):  
Sudeep Shukla ◽  
Alka Jadaun ◽  
Vikas Arora ◽  
Raj Kumar Sinha ◽  
Neha Biyani ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Toxicity Assessment ◽  
In Vitro Toxicity ◽  
Oxide Nanoparticles ◽  
Chitosan Oligosaccharide ◽  
In Vitro Toxicity Assessment

scholarly journals Multiphysics Flow Modeling and in Vitro Toxicity of Iron Oxide Nanoparticles Coated with Poly(vinyl alcohol)

2009 ◽  
Vol 113 (6) ◽  
pp. 2322-2331 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Mohammad A. Shokrgozar ◽  
Abdolreza Simchi ◽  
Mohammad Imani ◽  
Abbas S. Milani ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
In Vitro Toxicity ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Flow Modeling

Green fabrication of iron oxide nanoparticles using grey mangrove Avicennia marina for antibiofilm activity and in vitro toxicity

2019 ◽  
Vol 15 ◽  
pp. 70-77 ◽  
Author(s):  
Vaikundamoorthy Ramalingam ◽  
Pandurangan Dhinesh ◽  
Subramaniam Sundaramahalingam ◽  
Rajendran Rajaram
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Avicennia Marina ◽  
In Vitro Toxicity ◽  
Oxide Nanoparticles ◽  
Antibiofilm Activity ◽  
Grey Mangrove

scholarly journals In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells

2016 ◽  
Vol 5 (1) ◽  
pp. 235-247 ◽  
Author(s):  
Gözde Kiliç ◽  
Carla Costa ◽  
Natalia Fernández-Bertólez ◽  
Eduardo Pásaro ◽  
João Paulo Teixeira ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Neuronal Cells ◽  
In Vitro Toxicity ◽  
Oxide Nanoparticles ◽  
Toxicity Evaluation ◽  
Diagnosis And Therapy

Iron oxide nanoparticles (ION) have been widely used in biomedical applications, for both diagnosis and therapy, due to their unique magnetic properties.

scholarly journals Multiphysics Flow Modeling and in Vitro Toxicity of Iron Oxide Nanoparticles Coated with Poly(vinyl alcohol)

2009 ◽  
Vol 113 (39) ◽  
pp. 17274-17274 ◽  
Author(s):  
Morteza Mahmoudi ◽  
Mohammad A. Shokrgozar ◽  
Abdolreza Simchi ◽  
Mohammad Imani ◽  
Abbas S. Milani ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Vinyl Alcohol ◽  
In Vitro Toxicity ◽  
Poly Vinyl Alcohol ◽  
Oxide Nanoparticles ◽  
Flow Modeling

scholarly journals Correction: In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells

2016 ◽  
Vol 5 (4) ◽  
pp. 1256-1256
Author(s):  
Gözde Kiliç ◽  
Carla Costa ◽  
Natalia Fernández-Bertólez ◽  
Eduardo Pásaro ◽  
João Paulo Teixeira ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Neuronal Cells ◽  
In Vitro Toxicity ◽  
Oxide Nanoparticles ◽  
Toxicity Evaluation

Correction for ‘In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells’ by Gözde Kiliç et al., Toxicol. Res., 2016, 5, 235–247.

Polymer Coated Iron Nanoparticles: Radiolabeling & In Vitro Studies

2020 ◽  
Vol 13 ◽  
Author(s):  
Selin Yılmaz ◽  
Çiğdem İçhedef ◽  
Kadriye Buşra Karatay ◽  
Serap Teksöz
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Iron Oxide ◽  
Cancer Cells ◽  
Iron Oxide Nanoparticles ◽  
Breast Cancer Cells ◽  
Cancer Drug ◽  
Oxide Nanoparticles ◽  
Sem Images

Backgorund: Superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used for targeted drug delivery systems due to their unique magnetic properties. Objective: In this study, it’s aimed to develop a novel targeted 99mTc radiolabeled polymeric drug delivery system for Gemcitabine (GEM). Methods: Gemcitabine, an anticancer agent, was encapsulated into polymer nanoparticles (PLGA) together with iron oxide nanoparticles via double emulsion technique and then labeled with 99mTc. SPIONs were synthesized by reduction–coprecipitation method and encapsulated with oleic acid for surface modification. Size distribution and the morphology of the synthesized nanoparticles were caharacterized by dynamic light scattering(DLS)and scanning electron microscopy(SEM), respectively. Radiolabeling yield of SPION-PLGAGEM nanoparticles were determined via Thin Layer Radio Chromatography (TLRC). Cytotoxicity of GEM loaded SPION-PLGA were investigated on MDA-MB-231 and MCF7 breast cancer cells in vitro. Results: SEM images displayed that the average size of the drug-free nanoparticles was 40 nm and the size of the drug-loaded nanoparticles was 50 nm. The diameter of nanoparticles were determined as 366.6 nm by DLS, while zeta potential was found as-29 mV. SPION was successfully coated with PLGA, which was confirmed by FTIR. GEM encapsulation efficiency of SPION-PLGA was calculated as 4±0.16 % by means of HPLC. Radiolabeling yield of SPION-PLGA-GEM nanoparticles were determined as 97.8±1.75 % via TLRC. Cytotoxicity of GEM loaded SPION-PLGA were investigated on MDA-MB-231 and MCF7 breast cancer cells. SPION-PLGA-GEM showed high uptake on MCF-7, whilst incorporation rate was increased for both cell lines which external magnetic field application. Conclusion: 99mTc labeled SPION-PLGA nanoparticles loaded with GEM may overcome some of the obstacles in anti-cancer drug delivery because of their appropriate size, non-toxic, and supermagnetic characteristics.

Shaping and Cellular Uptake of Folic Acid Coated Gold and Magnetite Nanoparticles

2019 ◽  
Vol 9 (2) ◽  
pp. 166-172
Author(s):  
Ahmed A.G. El-Shahawy ◽  
Gamal Elghnam ◽  
Alsayed A.M. Alsherbini
Keyword(s):  
Folic Acid ◽  
Iron Oxide ◽  
Tumor Cells ◽  
Iron Oxide Nanoparticles ◽  
Individual Cell ◽  
Oxide Nanoparticles ◽  
Cellular Compartment ◽  
Specific Tumor ◽  
Uv Visible

Background:Gold and Iron Oxide nanoparticles NPs play as nanocarriers for a specific drug delivery and contrast agents. Intercellular uptake of these nanoparticles and targeting to individual cell and sub-cellular compartment is essential.Objective:The aim of the current study is to evaluate the intracellular uptake of these NPs to specific tumor cells in vitro conjugated with folic acid with a goal of enhancing the efficiency of specific targeting to tumor cells.Methods:We synthesized the nanoparticles by a chemical method and characterized by UV-Visible, FTIR, XRD, and TEM.Results & Conclusion:The results revealed the conjugation of Gold and Iron Oxide nanoparticles with folic acid increased the intercellular uptake with high percent compared to non- conjugated nanoparticles.

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