scholarly journals Hepatoprotective effect of methanolic Tanacetum parthenium extract on CCl4-induced liver damage in rats

2017 ◽  
Vol 4 ◽  
pp. 455-462 ◽  
Author(s):  
Yavar Mahmoodzadeh ◽  
Mohammad Mazani ◽  
Lotfollah Rezagholizadeh
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effect ◽  
Tanacetum Parthenium

scholarly journals Hepatoprotective Effect of Quercetin Pretreatment Against Paracetamol-Induced Liver Damage and Partial Hepatectomy in Rats

2017 ◽  
Vol 60 (0) ◽  
Author(s):  
Pedro Paulo Barros ◽  
Gustavo Henrique da Silva ◽  
Gisele Mara Silva Gonçalves ◽  
Jessica Cristiane Oliveira ◽  
Livia Gonçalves Pagnan ◽  
...  
Keyword(s):  
Partial Hepatectomy ◽  
Liver Damage ◽  
Hepatoprotective Effect

scholarly journals Hepatoprotective effect of Prunus armeniaca L. (Apricot) leaf extracts on Paracetamol induced liver damage in Wistar rats.

2016 ◽  
Vol 8 (2) ◽  
pp. 154-158 ◽  
Author(s):  
Varsha Raj ◽  
Arun Kumar Mishra ◽  
Amrita Mishra ◽  
Najam Ali Khan
Keyword(s):  
Liver Damage ◽  
Wistar Rats ◽  
Prunus Armeniaca ◽  
Hepatoprotective Effect ◽  
Leaf Extracts ◽  
Prunus Armeniaca L

scholarly journals Bamboo Stems (Phyllostachys nigra variety henosis) Containing Polyphenol Mixtures Activate Nrf2 and Attenuate Phenylhydrazine-Induced Oxidative Stress and Liver Injury

Nutrients ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 114 ◽  
Author(s):  
Ji Hye Yang ◽  
Moon-Hee Choi ◽  
Chang-Su Na ◽  
Sam Seok Cho ◽  
Jae Hoon Kim ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Liver Injury ◽  
Iron Overload ◽  
Liver Damage ◽  
Hepg2 Cells ◽  
Hepatoprotective Effect ◽  
Glutathione Depletion ◽  
Related Factor ◽  
Nrf2 Target Gene ◽  
Phyllostachys Nigra

This study was designed to investigate the hepatoprotective effect of bamboo stems using in vitro and in vivo experimental liver damage models. Ethyl acetate fraction of 80% ethanol extract of Phyllostachys nigra stem (PN3) containing polyphenols had a higher NQO1-ARE reporter gene activity as monitored by the activity of the NF-E2-related factor (Nrf2) antioxidant pathway in cells in comparison to extracts from other species and under other conditions. The Nrf2 was translocated from the cytosol to the nucleus in response to PN3, followed by induction of the Nrf2 target gene expression, including HO-1, GCL, and NQO-1 in HepG2 cells. Phosphorylation of Nrf2 in HepG2 cells was enhanced in PN3, which was mediated by PKCδ, ERK, and p38 MAPK. Consequently, PN3 inhibited arachidonic acid (AA) + iron-induced reactive oxygen species generation and glutathione depletion, and, thus, highlighted their role in cytotoxicity. Treatment with major polyphenols of PN3, including catechin, chlorogenic acid, caffeic acid, and p-coumaric acid, also improved AA + iron-mediated oxidative stress and, thus, improved cell viability. Treatment with phenylhydrazine in mice, i.e., the iron overload liver injury model, increased plasma alanine aminotransferase and aspartate aminotransferase levels and changed histological features in mice—a response that was almost completely blocked by PN3 administration. Moreover, PN3 extract mitigated phenylhydrazine-induced oxidative stress and inflammatory responses. Conclusively, PN3 can exert a hepatoprotective effect against iron overload-induced acute liver damage due to its antioxidant properties.

Hepatoprotective effect of ethanolic extract ofEclipta alba on experimental liver damage in rats and mice

1993 ◽  
Vol 7 (2) ◽  
pp. 154-158 ◽  
Author(s):  
B. Singh ◽  
A. K. Saxena ◽  
B. K. Chandan ◽  
S. G. Agarwal ◽  
M. S. Bhatia ◽  
...  
Keyword(s):  
Liver Damage ◽  
Ethanolic Extract ◽  
Hepatoprotective Effect ◽  
Rats And Mice ◽  
Experimental Liver ◽  
Experimental Liver Damage

The Hepatoprotective Effect of Ethanolic Bark Extract of Terminalia arjuna on Paracetamol Induced Liver Damage

2011 ◽  
Vol 8 (2) ◽  
pp. 777-781
Author(s):  
S.P. Sangamithira ◽  
J. Revathy ◽  
S. Sheik Abdullah ◽  
P. Sampath Kumar
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effect ◽  
Bark Extract ◽  
Terminalia Arjuna

scholarly journals Hepatoprotective Effect of Opuntia robusta and Opuntia streptacantha Fruits against Acetaminophen-Induced Acute Liver Damage

Nutrients ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 607 ◽  
Author(s):  
Herson González-Ponce ◽  
María Martínez-Saldaña ◽  
Ana Rincón-Sánchez ◽  
María Sumaya-Martínez ◽  
Manon Buist-Homan ◽  
...  
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effect ◽  
Acute Liver Damage

scholarly journals Antioxidant and Hepatoprotective Effect of Penthorum chinense Pursh Extract against t-BHP-Induced Liver Damage in L02 Cells

Molecules ◽  
2015 ◽  
Vol 20 (4) ◽  
pp. 6443-6453 ◽  
Author(s):  
Yangyang Hu ◽  
Shengpeng Wang ◽  
Anqi Wang ◽  
Ligen Lin ◽  
Meiwan Chen ◽  
...  
Keyword(s):  
Liver Damage ◽  
Hepatoprotective Effect ◽  
Penthorum Chinense Pursh ◽  
Penthorum Chinense ◽  
L02 Cells

Hepatoprotective effect of Vitis vinifera L. leaves on carbon tetrachloride-induced acute liver damage in rats

2007 ◽  
Vol 112 (1) ◽  
pp. 145-151 ◽  
Author(s):  
Didem Deliorman Orhan ◽  
Nilüfer Orhan ◽  
Ender Ergun ◽  
Fatma Ergun
Keyword(s):  
Carbon Tetrachloride ◽  
Vitis Vinifera ◽  
Liver Damage ◽  
Hepatoprotective Effect ◽  
Vitis Vinifera L ◽  
Acute Liver Damage
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