Effect of Propranolol on the Relationship Between QT Interval and Vagal Modulation of Heart Rate Variability in Cirrhotic Patients Awaiting Liver Transplantation

The aims of this study were to verify the correspondence between heart rate variability (HRV) and ventilatory thresholds during a progressive exercise test and the relationship with low and high aerobic fitness levels. Twenty male volunteers (29.5±6.2 years; 75.9±13.0 kg; 175.0±7.4 cm) were recruited. The subjects were allocated to two groups according to their VO2max <48.8 ml•kg−1•min−1 (low cardiorespiratory fitness group) (n=10) and >48.81 ml•kg−1•min−1 (high cardiorespiratory fitness group) (n=10). A progressive test was performed, consisting of 3-min stages beginning at 25 watts and increasing by 25 watts every 3-min. The HRV threshold (HRVT) and ventilatory threshold (VT) analyses were performed through visual inspection. The comparisons with RMSSD values in percentage of maximum workload resulted in a higher effect size (ES) than the SDNN values. The VO2 in the high cardiorespiratory fitness group at VT (+32%), HRVTRMSSD (+27%), and HRVTSDNN (+31%) was signifi cantly higher compared to the group with low cardiorespiratory fitness. Higher values were observed for relative load (W•kg-1) at VT and HRVTSDNN in the high cardiorespiratory fitness group in comparison with the low cardiorespiratory fitness group (P<0.05), but no difference for VT and HRVTRMSSD. Signifi cant correlations between at VT and HRVTSDNN (r=0.77) were found only in the low cardiorespiratory fitness group. Cardiorespiratory fitness should be regarded as a factor for HRVT evaluation. The HRVTSDNN was closer to the VT in the low cardiorespiratory fitness group than the HRVTRMSSD, however, the use of vagal modulation assessed using the HRV parameter was more sensitive to observe possible differences regarding cardiorespiratory fitness.

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Influence of aerobic fitness on the correspondence between heart rate variability and ventilatory threshold

Revista Brasileira de Educação Física e Esporte ◽

10.11606/issn.1981-4690.v34i4p555-566 ◽

2020 ◽

Vol 34 (4) ◽

pp. 555-566

Author(s):

Lúcio Flávio Soares-Caldeira ◽

Carla Cristiane da Silva ◽

Priscila Chierotti ◽

Nicolle de Souza Dias ◽

Fábio Yuzo Nakamura

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Cardiorespiratory Fitness ◽

Aerobic Fitness ◽

Visual Inspection ◽

Ventilatory Threshold ◽

Vagal Modulation ◽

Maximum Workload ◽

Progressive Exercise ◽

The Relationship

The aims of this study were to verify the correspondence between heart rate variability (HRV) and ventilatory thresholds during a progressive exercise test and the relationship with low and high aerobic fitness levels. Twenty male volunteers (29.5±6.2 years; 75.9±13.0 kg; 175.0±7.4 cm) were recruited. The subjects were allocated to two groups according to their VO2max <48.8 ml•kg−1•min−1 (low cardiorespiratory fitness group) (n=10) and >48.81 ml•kg−1•min−1 (high cardiorespiratory fitness group) (n=10). A progressive test was performed, consisting of 3-min stages beginning at 25 watts and increasing by 25 watts every 3-min. The HRV threshold (HRVT) and ventilatory threshold (VT) analyses were performed through visual inspection. The comparisons with RMSSD values in percentage of maximum workload resulted in a higher effect size (ES) than the SDNN values. The VO2 in the high cardiorespiratory fitness group at VT (+32%), HRVTRMSSD (+27%), and HRVTSDNN (+31%) was signifi cantly higher compared to the group with low cardiorespiratory fitness. Higher values were observed for relative load (W•kg-1) at VT and HRVTSDNN in the high cardiorespiratory fitness group in comparison with the low cardiorespiratory fitness group (P<0.05), but no difference for VT and HRVTRMSSD. Signifi cant correlations between at VT and HRVTSDNN (r=0.77) were found only in the low cardiorespiratory fitness group. Cardiorespiratory fitness should be regarded as a factor for HRVT evaluation. The HRVTSDNN was closer to the VT in the low cardiorespiratory fitness group than the HRVTRMSSD, however, the use of vagal modulation assessed using the HRV parameter was more sensitive to observe possible differences regarding cardiorespiratory fitness.

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QT interval prolongation and decreased heart rate variability in cirrhotic patients: relevance of hepatic venous pressure gradient and serum calcium

Clinical Science ◽

10.1042/cs20080325 ◽

2009 ◽

Vol 116 (12) ◽

pp. 851-859 ◽

Cited By ~ 56

Author(s):

Simonetta Genovesi ◽

Daniela M. Prata Pizzala ◽

Massimo Pozzi ◽

Laura Ratti ◽

Maria Milanese ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Pressure Gradient ◽

Qt Interval ◽

Venous Pressure ◽

Plasma Calcium ◽

Interval Prolongation ◽

Qtc Prolongation ◽

Qt Interval Prolongation ◽

Cirrhotic Patients

A prolongation of QT interval has been shown in patients with cirrhosis and it is considered as part of the definition of the so-called ‘cirrhotic cardiomyopathy’. The aim of the present study was to assess the determinants of QT interval prolongation in cirrhotic patients. Forty-eight male patients with different stages of liver disease were divided into three subgroups according to the Child–Pugh classification. All patients underwent a 24-h ECG Holter recording. The 24-h mean of QT intervals corrected for heart rate (termed QTc) and the slope of the regression line QT/RR were calculated. HRV (heart rate variability), plasma calcium and potassium concentration and HVPG (hepatic venous pressure gradient) were measured. QTc was progressively prolonged from Child A to Child C patients (P=0.001). A significant correlation between QTc and HVPG was found (P=0.003). Patients with alcohol-related cirrhosis presented QTc prolongation more frequently than patients with post-viral cirrhosis (P<0.001). The QT/RR slope was steeper in subjects with alcoholic aetiology as compared with viral aetiology (P=0.02), suggesting that these patients have a further QTc prolongation when heart rate decreases. The plasma calcium concentration was inversely correlated with QTc (P<0.001). The presence of severe portal hypertension was associated with decreased HRV (P<0.001). Cirrhotic patients with a more severe disease, especially of alcoholic aetiology, who have greater HVPG and lower calcium plasma levels, have an altered ventricular repolarization and a reduced vagal activity to the heart, which may predispose to life-threatening arrhythmias.

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The relationship between effects of heat on performance, core temperature and heart rate variability.

PsycEXTRA Dataset ◽

10.1037/e422042004-001 ◽

1990 ◽

Author(s):

Shahram Razmjou ◽

Anders Kjellberg

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Core Temperature ◽

The Relationship

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The Relationship Between Mindfulness and Heart Rate Variability

PsycEXTRA Dataset ◽

10.1037/e566842012-338 ◽

2010 ◽

Author(s):

Erin V. Rodgers ◽

Raymond Fleming ◽

Aaryn R. Schuster

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

The Relationship

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The Relationship Among Electroencephalography,Skin Conductance Response,Heart Rate Variability and Mental Health Among Smartphone Users After Receiving Texting or Calling

Case Medical Research ◽

10.31525/ct1-nct04133597 ◽

2019 ◽

Author(s):

Keyword(s):

Mental Health ◽

Heart Rate ◽

Heart Rate Variability ◽

Skin Conductance ◽

Skin Conductance Response ◽

The Relationship

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The Relationship between Heart Rate Variability and Metabolic Syndrome at a Rural Area

Korean Journal of Occupational and Environmental Medicine ◽

10.35371/kjoem.2004.16.4.459 ◽

2004 ◽

Vol 16 (4) ◽

pp. 459

Author(s):

Kyoung Bok Min ◽

Jin Young Min ◽

Kyung Hee Jung-Choi ◽

Hyung Joon Jhun ◽

Sung Il Cho ◽

...

Keyword(s):

Metabolic Syndrome ◽

Heart Rate ◽

Heart Rate Variability ◽

Rural Area ◽

The Relationship

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Indices of Heart Rate Variability and Performance During a Response-Conflict Task Are Differently Associated With ADHD and Autism

Journal of Attention Disorders ◽

10.1177/1087054720972793 ◽

2021 ◽

pp. 108705472097279

Author(s):

Alessio Bellato ◽

Iti Arora ◽

Puja Kochhar ◽

Chris Hollis ◽

Madeleine J. Groom

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Sensory Information ◽

Response Conflict ◽

Mediation Model ◽

Conflict Task ◽

Accurate Performance ◽

And Performance ◽

Comorbid Adhd ◽

The Relationship

We investigated autonomic arousal, attention and response conflict, in ADHD and autism. Heart rate variability (HRV), and behavioral/electrophysiological indices of performance, were recorded during a task with low and high levels of response conflict in 78 children/adolescents (7–15 years old) with ADHD, autism, comorbid ADHD+autism, or neurotypical. ANOVA models were used to investigate effects of ADHD and autism, while a mediation model was tested to clarify the relationship between ADHD and slower performance. Slower and less accurate performance characterized ADHD and autism; however, atypical electrophysiological indices differently characterized these conditions. The relationship between ADHD and slower task performance was mediated by reduced HRV in response to the cue stimulus. Autonomic hypo-arousal and difficulties in mobilizing energetic resources in response to sensory information (associated with ADHD), and atypical electrophysiological indices of information processing (associated with autism), might negatively affect cognitive performance in those with ADHD+autism.

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