Three-Dimensional Transvaginal Tomographic Ultrasound Imaging for Cervical Cancer Staging

2015 ◽  
Vol 41 (9) ◽  
pp. 2303-2309 ◽  
Author(s):  
Xue-Song Han ◽  
Chun-Ping Ning ◽  
Li-Tao Sun ◽  
Xiao-Ying Li ◽  
Yan-Qing Peng ◽  
...  
2008 ◽  
Vol 32 (3) ◽  
pp. 413-413
Author(s):  
F. M. Andrade ◽  
S. G. A. Andrade ◽  
L. C. S. Bussamra ◽  
M. M. Barbosa ◽  
T. A. A. Faria ◽  
...  

2008 ◽  
Vol 32 (3) ◽  
pp. 412-412
Author(s):  
F. M. Andrade ◽  
S. G. A. Andrade ◽  
W. J. Hisaba ◽  
M. W. Mattos ◽  
M. R. Kataguiri ◽  
...  

Author(s):  
Armando Pintucci ◽  
FNU Vincenzo ◽  
D Addario ◽  
Vincenzo Pinto ◽  
Luca Di Cagno

Abstract Three-dimensional ultrasound is the most innovating and attracting modality in the field of ultrasound imaging and represents a superb tool to perform an accurate fetal neuroscan. Once the fetal brain has been scanned, it is then possible to “navigate” in the stored volume choosing among the multiple scanning planes on the three orthogonal spatial axes. Last generation 3D equipments have multiple software facilities which are extremely useful to correctly evaluate the fetal brain such as the multiplanar view, the tomographic ultrasound imaging (TUI), the volume contrast imaging in the C plane (VCI-C plane), the volume calculation, the surface rendering, the 3D color and power Doppler. Thanks to these imaging modalities it is possible to evaluate the finest anatomical details of the developing brain and to increase the diagnostic accuracy when an abnormal sonographic finding of the fetal brain is recognized during the routine examination.


2008 ◽  
Vol 32 (3) ◽  
pp. 402-402
Author(s):  
F. M. Andrade ◽  
S. G. A. Andrade ◽  
L. C. S. Bussamra ◽  
M. M. Barbosa ◽  
A. Amaro ◽  
...  

2018 ◽  
Vol 64 (5) ◽  
pp. 645-650
Author(s):  
Olga Kravets ◽  
Yelena Romanova ◽  
Oleg Kozlov ◽  
Mikhail Nechushkin ◽  
A. Gavrilova ◽  
...  

We present our results of 3D CT/MRI brachytherapy (BT) planning in 115 patients with locally advanced cervical cancer T2b-3bN0-1M0. The aim of this study was to assess the differences in the visualization of tumor target volumes and risk organs during the 3D CT/MRI BT. The results of the study revealed that the use of MRI imaging for dosimetric planning of dose distribution for a given volume of a cervical tumor target was the best method of visualization of the soft tissue component of the tumor process in comparison with CT images, it allowed to differentially visualize the cervix and uterine body, directly the tumor volume. Mean D90 HR-CTV for MRI was 32.9 cm3 versus 45.9 cm3 for CT at the time of first BT, p = 0.0002, which is important for local control of the tumor process. The contouring of the organs of risk (bladder and rectum) through MRI images allows for more clearly visualizing the contours, which statistically significantly reduces the dose load for individual dosimetric planning in the D2cc control volume, і.є. the minimum dose of 2 cm3 of the organ of risk: D2cc for the bladder was 24.3 Gy for MRI versus 34.8 Gy on CT (p = 0.045); D2cc for the rectum - 18.7 Gy for MRI versus 26.8 Gy for CT (p = 0.046). This is a prognostically important stage in promising local control, which allows preventing manifestation of radiation damage.


Biomolecules ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 37
Author(s):  
An-Jen Chiang ◽  
Chia-Jung Li ◽  
Kuan-Hao Tsui ◽  
Chung Chang ◽  
Yuan-chin Ivan Chang ◽  
...  

Cervical cancer is a common gynecological malignancy, accounting for 10% of all gynecological cancers. Recently, targeted therapy for cervical cancer has shown unprecedented advantages. Several studies have shown that ubiquitin conjugating enzyme E2 (UBE2C) is highly expressed in a series of tumors, and participates in the progression of these tumors. However, the possible impact of UBE2C on the progression of cervical squamous cell carcinoma (CESC) remains unclear. Here, we carried out tissue microarray analysis of paraffin-embedded tissues from 294 cervical cancer patients with FIGO/TNM cancer staging records. The results indicated that UBE2C was highly expressed in human CESC tissues and its expression was related to the clinical characteristics of CESC patients. Overexpression and knockdown of UBE2C enhanced and reduced cervical cancer cell proliferation, respectively, in vitro. Furthermore, in vivo experiments showed that UBE2C regulated the expression and activity of the mTOR/PI3K/AKT pathway. In summary, we confirmed that UBE2C is involved in the process of CESC and that UBE2C may represent a molecular target for CESC treatment.


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