Which factors predict upper urinary tract deterioration in overactive neurogenic bladder dysfunction?

Urology ◽  
2005 ◽  
Vol 66 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Burak Özkan ◽  
Oktay Demirkesen ◽  
Haydar Durak ◽  
Nesrin Uygun ◽  
Vasif Ismailoglu ◽  
...  
2012 ◽  
Vol 2012 ◽  
pp. 1-16 ◽  
Author(s):  
Peter T. Dorsher ◽  
Peter M. McIntosh

Congenital anomalies such as meningomyelocele and diseases/damage of the central, peripheral, or autonomic nervous systems may produce neurogenic bladder dysfunction, which untreated can result in progressive renal damage, adverse physical effects including decubiti and urinary tract infections, and psychological and social sequelae related to urinary incontinence. A comprehensive bladder-retraining program that incorporates appropriate education, training, medication, and surgical interventions can mitigate the adverse consequences of neurogenic bladder dysfunction and improve both quantity and quality of life. The goals of bladder retraining for neurogenic bladder dysfunction are prevention of urinary incontinence, urinary tract infections, detrusor overdistension, and progressive upper urinary tract damage due to chronic, excessive detrusor pressures. Understanding the physiology and pathophysiology of micturition is essential to select appropriate pharmacologic and surgical interventions to achieve these goals. Future perspectives on potential pharmacological, surgical, and regenerative medicine options for treating neurogenic bladder dysfunction are also presented.


Author(s):  
Elena V. Novikova ◽  
Maya A. Khan ◽  
Irina I. Ivanova ◽  
Olga V. Trunova

Background. After operations on the ureter, it is important to use medical rehabilitation technologies aimed at preventing urodynamic disorders of the upper and lower urinary tract, stimulating reparative processes. In recent years, special attention has been drawn to high-intensity pulsed magnetotherapy, which has a more pronounced and long-lasting stimulating effect compared to other types of electrical stimulation. Aim: to substantiate the feasibility of including high-intensity pulsed magnetic therapy in the comprehensive medical rehabilitation of children with hydronephrosis and concomitant neurogenic bladder dysfunction. Methods. Clinical observations and special studies with the inclusion of high-intensity pulse magnetic therapy in the course of therapy were conducted in 100 children aged 4 to 15 years with hydronephrosis, a condition after surgery. Results. Medical rehabilitation with the inclusion of high-intensity pulsed magnetic therapy had a positive effect on the urodynamics of the urinary tract, renal blood flow, helped to stop inflammation in the renal parenchyma and restore the rhythm of urination in children with hydronephrosis and concomitant neurogenic bladder dysfunction. Conclusion. According to the research results, the feasibility of including high-intensity pulsed magnetic therapy in the complex of medical rehabilitation of children with hydronephrosis, concomitant neurogenic bladder dysfunction, is scientifically justified.


PEDIATRICS ◽  
1975 ◽  
Vol 55 (2) ◽  
pp. 300-301
Author(s):  
Robert L. Lebowitz

It is important to recognize the patient with sacral agenesis and associated neurogenic bladder dysfunction before irremediable damage to the urinary tract occurs, as stressed by Thompson, Kirk, and Dale.1 It is also true that this entity is often occult. Thus, any clue to the diagnosis, or statistical association with another clinical problem, is of great help in identifying patients with this malformation, aptly termed "the syndrome of caudal regression" by Duhamel. Thompson, Kirk, and Dale failed to point out the striking incidence of sacral agenesis in infants of diabetic mothers, first noted in this journal by Rusnak and Driscoll.


2020 ◽  
Vol 12 (4) ◽  
Author(s):  
Mitra Naseri ◽  
Gholam Reza Sarvari ◽  
Niayesh Tafazoli ◽  
Nooshin Tafazoli

Background: Urinary tract infections (UTIs) with non-Escherichia coli (E. coli) species are associate with urological abnormalities. Objectives: To compare the prevalence of non-E. coli infections in patients with urological anomalies, neurogenic bladder dysfunction, and those with apparently normal urinary systems. Methods: Pediatric nephrology clinic at a tertiary-care center in east of Iran. Children affected by UTI enrolled from 2003 to 2016. The results of urine culture were noted at enrolment. Cases with nephrolithiasis who had normal voiding cystourethrogram were excluded. After the implementation of imaging and urodynamic examinations, 832 patients enrolled according to the following inclusion criteria: cases with vesicoureteral reflux, urinary obstruction, neurogenic bladder, and patients with apparently normal urinary tract. The prevalence of infections with E. coli vs. non-E. coli pathogens were compared between different groups of enrolled cases. Results: In this study, 62.26% of the subjects had a normal urinary system, while 33.77%, 3.97%, and 2.4% of whom had vesicoureteral reflux, neurogenic bladder, and obstruction, respectively. Non-E. coli pathogens were responsible for infections in 17.29%, 19.39%, 33.74%, and 17.15% of these cases, respectively. Infections with non-E. coli pathogens were significantly more prevalent in cases with neurogenic bladder (P = 0.003). Pseudomonas species were responsible for 4/125, 5/118, 5/28, and 0/6 episodes of non-E. coli infections in cases with apparently normal urinary system, patients with vesicoureteral reflux, cases with neurogenic bladder, and those with urinary obstruction, respectively (P = 0.004). Conclusions: Infections with non-E. coli and also Pseudomonas species are significantly more prevalent in patients with neurogenic bladder dysfunction rather than those with urological abnormalities and/or cases with apparently normal urinary system.


Sign in / Sign up

Export Citation Format

Share Document