Endoscopic Management of Low-Grade Upper Tract Urothelial Carcinoma: Characterizing the Long-term Burden of Care in Comparison to Radical Nephroureterectomy

Urology ◽  
2021 ◽  
Author(s):  
Chen Shenhar ◽  
Yotam Veredgorn ◽  
Shir Bulis ◽  
Tzach Aviv ◽  
Abd Elhalim Darawsha ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Endoscopic Management ◽  
Low Grade ◽  
Radical Nephroureterectomy ◽  
Burden Of Care ◽  
Upper Tract

The Impact of Hospital Volume on Short-term and Long-term Outcomes for Patients Undergoing Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma

Urology ◽  
2021 ◽  
Vol 147 ◽  
pp. 135-142
Author(s):  
Wilson Sui ◽  
Christopher J.D. Wallis ◽  
Amy N. Luckenbaugh ◽  
Daniel A. Barocas ◽  
Sam S. Chang ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Hospital Volume ◽  
Upper Tract Urothelial Carcinoma ◽  
Radical Nephroureterectomy ◽  
Long Term Outcomes ◽  
Short Term ◽  
Upper Tract ◽  
The Impact

UP-2.101: Endoscopic Management for Upper Tract Urothelial Carcinoma: Long-Term Follow-Up in a Single Center

Urology ◽  
2009 ◽  
Vol 74 (4) ◽  
pp. S262
Author(s):  
S. Uehara ◽  
T. Watanabe ◽  
T. Saika ◽  
M. Araki ◽  
K. Monden ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Endoscopic Management ◽  
Single Center ◽  
Upper Tract ◽  
Long Term Follow Up

Long-Term Outcome of Hand-Assisted Laparoscopic Radical Nephroureterectomy for Upper-Tract Urothelial Carcinoma: Comparison with Open Surgery

2007 ◽  
Vol 21 (6) ◽  
pp. 595-599 ◽  
Author(s):  
Shiu-Dong Chung ◽  
Shih-Chieh Chueh ◽  
Ming-Kuen Lai ◽  
Chao-Yuan Huang ◽  
Yeong-Shiau Pu ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Open Surgery ◽  
Upper Tract Urothelial Carcinoma ◽  
Radical Nephroureterectomy ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Upper Tract

Long-term endoscopic management of upper tract urothelial carcinoma: 20-year single-centre experience

2012 ◽  
Vol 110 (11) ◽  
pp. 1608-1617 ◽  
Author(s):  
Mark L. Cutress ◽  
Grant D. Stewart ◽  
Simon Wells-Cole ◽  
Simon Phipps ◽  
Ben G. Thomas ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Endoscopic Management ◽  
Single Centre ◽  
Upper Tract ◽  
Single Centre Experience

scholarly journals Long-term ureteroscopic management of upper tract urothelial carcinoma: 28-year single-centre experience

2020 ◽  
Vol 51 (1) ◽  
pp. 130-137
Author(s):  
Yuki Maruyama ◽  
Motoo Araki ◽  
Koichiro Wada ◽  
Kasumi Yoshinaga ◽  
Yosuke Mitsui ◽  
...  
Keyword(s):  
Overall Survival ◽  
Urothelial Carcinoma ◽  
Upper Tract Urothelial Carcinoma ◽  
Endoscopic Management ◽  
Survival Outcomes ◽  
Cancer Specific Survival ◽  
Upper Tract ◽  
Non Invasive

Abstract Background Long-term survival outcomes of patients who undergo endoscopic management of non-invasive upper tract urothelial carcinoma remain uncertain. The longest mean follow-up period in previous studies was 6.1 years. This study reports the long-term outcomes of patients with upper tract urothelial carcinoma who underwent ureteroscopic ablation at a single institution over a 28-year period. Methods We identified all patients who underwent ureteroscopic management of upper tract urothelial carcinoma as their primary treatment at our institution between January 1991 and April 2011. Survival outcomes, including overall survival, cancer-specific survival, upper-tract recurrence-free survival and renal unit survival, were estimated using Kaplan−Meier methodology. Results A total of 15 patients underwent endoscopic management, with a mean age at diagnosis of 66 years. All patients underwent ureteroscopy, and biopsy-confirmed pathology was obtained. Median (range; mean) follow-up was 11.7 (2.3–20.9, 11.9) years. Upper tract recurrence occurred in 87% (n = 13) of patients. Twenty percent (n = 3) of patients proceeded to nephroureterectomy. The estimated cancer-specific survival rate was 93% at 5, 10, 15 and 20 years. Estimated overall survival rates were 86, 80, 54 and 20% at 5, 10, 15 and 20 years. Only one patient experienced cancer-specific mortality. The estimated mean and median overall survival times were 14.5 and 16.6 years, respectively. The estimated mean cancer-specific survival time was not reached. Conclusions Although upper tract recurrence is common, endoscopic management of non-invasive upper tract urothelial carcinoma provides a 90% cancer-specific survival rate at 20 years in selected patients.

scholarly journals 532 nm green-light laser vaporization of upper tract urothelial carcinoma

BMC Urology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
F. Dursun ◽  
M. M. Pan ◽  
M. Morgan ◽  
R. R. Gonzalez ◽  
R. Satkunasivam
Keyword(s):  
Urothelial Carcinoma ◽  
Left Kidney ◽  
Upper Tract Urothelial Carcinoma ◽  
Laser Vaporization ◽  
Endoscopic Management ◽  
Low Grade ◽  
Continuous Irrigation ◽  
Upper Tract ◽  
Clinical Scenarios ◽  
532 Nm

Abstract Background Endoscopic management of low risk upper tract urothelial carcinoma (UTUC) may be considered in select clinical scenarios, which allows sparing the morbidity of radical nephroureterectomy while achieving acceptable oncological outcomes and preservation of kidney function. Herein, we present a case with UTUC in a solitary kidney managed with 532 nm laser vaporization through a percutaneous approach. Case presentation The patient in this video (Additional file 1) is an 85-year-old woman who presented with a bulky tumor in the collecting system of a congenital solitary left kidney, which was a biopsy proven low grade urothelial carcinoma. Prior to the procedure, a lower pole percutaneous nephrostomy tube was successfully placed under sedation by Interventional Radiology. The procedure was done in a prone split leg position. The mass, which was predominantly localized to the renal pelvis was efficiently vaporized with the 532 nm laser in a systematic manner with continuous irrigation of normal saline through the cystoscope. The patient was discharged home on postoperative day 2 with the nephroureterostomy catheter open to drainage. This catheter was subsequently clamped and removed two weeks later without complications. Follow up uretroscopy showed excellent treatment response and the patient remains well without complications. Conclusion This case report details the potential utility of 532 nm laser vaporization of UTUC, however, ongoing studies are required to demonstrate peri-operative safety and durable oncologic efficacy.

scholarly journals Importance of long-term follow-up after endoscopic management for upper tract urothelial carcinoma and factors leading to surgical management

2020 ◽  
Vol 52 (8) ◽  
pp. 1465-1469
Author(s):  
Anand Mohapatra ◽  
Seth A. Strope ◽  
Nick Liu ◽  
Andrew Winer ◽  
Nicole E. Benfante ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Surgical Management ◽  
Upper Tract Urothelial Carcinoma ◽  
Endoscopic Management ◽  
Upper Tract ◽  
Long Term Follow Up
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