Continuous intraventricular vancomycin for treatment of ventriculitis using IRRAflow®: A case report

Background: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. Case Description: We present the case of a 66-year-old man who presented with altered mental status and progressively became comatose. He was found to have fulminant ventriculitis due to a ruptured intracranial abscess. He was treated with bilateral IRRAflow® catheter (IRRAS, Stockholm, Sweden) placement through which continuous irrigation with vancomycin was initiated. Conclusion: This treatment was safe and led to improvement in the patient’s neurologic examination, imaging findings, and cerebrospinal fluid profiles.

Sustainable effective use of brackish and canal water for rice-wheat crop production and soil health

<p>A pot study was conducted to develop reasonable irrigation scheduling methods for rice-wheat crop rotation by conjunctive use of low-quality brackish water and good quality canal water. Treatments tested were; T₁ (canal water), T₂ (brackish water), T₃(brackish water for rice and canal water for wheat), T₄ (last two irrigations to rice, and initial two irrigations to wheat with canal water), T₅ (last two irrigations to rice but two initial and one last irrigation to wheat with canal water). Results revealed that irrigation with canal water resulted in the maximum mean biomass and grain yield of rice and wheat crops followed by cyclic use of brackish and canal water. While continuous irrigation with brackish water resulted the lowest mean biomass and grain yield. The different modes of irrigations also influenced chemical properties of soil, brackish water adversely affected the soil properties, and maximum pH of soil saturated paste (pH_s), electrical conductivity of soil extract (EC_e) and sodium adsorption ratio (SAR) were recorded where brackish water was used continuously. Therefore, it was concluded that when water is valuable and freshwater resources are limited, cyclic use of the canal and brackish water is also profitable with marginal effect on biomass and grain yield and proves least detrimental for soil health.</p>

Effect of irrigation methods and testing some rice cultivars against growth, root development and yield on rainfed Ultisols of Aceh Besar

The main obstacle in rice cultivation on dryland is the limitation of water availability and large fluctuation of groundwater availability. It causes plant metabolic processes to be hampered. The threat of such natural conditions can be overcomed by intensifying and using superior cultivars to adapt widely to the environment, such as being resistant to drought. This study aims to determine the effect of irrigation methods and the response of several different cultivars to growth, yield potential, and rice root systems. This research using a Split Plot Design pattern. The factors examined in this study were irrigation methods, which consisted of 3 levels of treatment, namely continuous irrigation (P1), intermittent irrigation (P2), and sprinkler irrigation (P3). Variety factors consisted of 4 levels, namely: Batutegi (V1), Situ Patenggang (V2), Inpago 5 (V3), and Sanbei (V4), so there were 12 treatment combinations with three repetitions of 36 treatment plot units. The results showed that the continuous and intermittent irrigation methods gave the highest yield per hectare and had the same weight, while the sprinkler gave the lowest yield per hectare, although not significantly different from other irrigation methods. The cultivar that gave the highest yield per hectare was Sanbei, while the lowest was Situ Patenggang, and the cultivar that gave the highest 1000 grain weight was Inpago-5, while the lowest was Sanbei, although it was not significantly different from other cultivars.

Abstract 1122‐000024: Stereotactic IntraCerebral Underwater Blood Aspiration Improves Survival Following Intracerebral Hemorrhage as Compared to Predicted Mortality

Introduction : Intracerebral hemorrhage (ICH) is a devastating form of neurological injury with substantial mortality. Recent publications on minimal invasive surgery (MIS) for hematoma evacuation have suggested survival benefits in select patients. Since 2015, our center has been performing an MIS technique using continuous irrigation with aspiration through an endoscope (SCUBA). SCUBA does not require a stability scan and can be performed despite hematoma expansion, intraventricular hemorrhage or radiographic spot sign. We present the 30‐day mortality of our initial experience and compare it to predicted mortality by presenting ICH score. Methods : We performed a retrospective review of consecutively admitted patients with spontaneous non‐traumatic supratentorial ICH who underwent SCUBA between 12/2015 – 03/2019. The primary outcome was observed 30‐day mortality compared to predicted mortality by ICH score on presentation. Key secondary outcomes were operative markers, hospital length of stay, and discharge disposition. Results : One hundred and fifteen patients were identified, with mean (SD) ICH volume of 51.4mL (33.9mL) and median ICH score of 2. The median evacuation was 97% of the hematoma volume and 85% of patients had a residual clot burden of less than 15mL. Twelve patients died within one month of SCUBA for an overall mortality rate of 10.4%. This was significantly lower than the predicted mortality by ICH score of 35.1%, with an absolute risk reduction of 24.7%. When analyzed by presenting ICH score, significant mortality benefits were observed for all ICH scores > 2, with more pronounced differences at higher ICH scores (Table 1). Conclusions : This study suggests that MIS with the SCUBA technique for ICH may reduce predicted 30‐day mortality, with a number need to treat of 4 to prevent one mortality. Further evaluation of this technique in a randomized clinical trial is required.

Assessment of post-operative analgesia in modified radical mastectomy patients using surgical wound irrigation with 0.25% bupivacaine

Modified Radical Mastectomy is the widely followed treatment for operable breast cancers. Among the methods used to alleviate pain, irrigation of wound with 0.25% Bupivacaine is one of the under-utilized methods with good efficiency compared to other drugs.To evaluate the role of local irrigation of 0.25% bupivacaine in alleviating the post-operative pain. This observational study was conducted among 60 female patients who underwent Modified Radical Mastectomy in a tertiary care teaching hospital between January 2017 and July 2018. Thirty (30) patients were randomly allotted to control group, where the routine post-operative pain management was followed. Another 30 were randomly allotted to study group where, before closure of the wound, a 20G scalp vein set was used along the length of the incision with multiple punctures in it for continuous irrigation with 0.25% Bupivacaine. Post operatively Visual analogue scale was used to measure the pain sensation at every six hours for 24 hours. The adverse effects like pain, hematoma, wound dehiscence, infection was noted on all the post-operative days.Both the groups were similar with respect to basic parameters measured. There was a significant reduction in need for rescue analgesia in the study group. There was a significant difference in mean VAS score between both groups from 6 hour of surgery. Post-operative nausea and vomiting was significantly less in the study group. Irrigation of wound with 0.25% Bupivacaine is found to reduce the pain sensation with minimal side effects without systemic compromise.

Effects of post-veraison irrigation on the phenolic composition of Vitis vinifera L. cv. ‘Xinomavro’ grapes

‘Xinomavro’ (the second planted red Greek variety behind ‘Agiorgitiko’) generally produces wines that are light in colour but with increased astringency, possibly related to grape flavonoid amount and composition; although irrigation is accepted as an effective means to enhance grape phenolic maturity, its role has not yet been sufficiently studied in the case of Xinomavro. This study aimed to determine the effect of post-veraison irrigation on berry anthocyanin and proanthocyanidin amount and composition, of field-grown Xinomavro vines (Vitis vinifera L.), under the typical summer conditions of Northern Greece. In a 10-year-old Xinomavro vineyard, two post-veraison watering regimes were applied—irrigation starting 20 days after veraison (mid-ripening irrigation, MRI) and irrigation starting immediately after veraison was completed (after veraison irrigation, AVI)—alongside non irrigated vines (NI), and vines irrigated continuously from berry set through harvest (continuous irrigation, CI). Proanthocyanidin composition was determined in both skins and seeds by employing phloroglucinolysis followed by HPLC-UV and MS detection (high-performance liquid chromatographic with tandem mass spectrometric and ultraviolet absorbance detection), and the anthocyanin profile was identified only in the skin extracts by HPLC-UV (high-performance liquid chromatographic with ultraviolet absorbance detection). Post-veraison irrigation increased yield parameters and reduced anthocyanin levels and the proportion of their stable forms (acylated vs. non-acylated, tri-oxygenated and methoxylated on the B-ring vs. di-oxygenated and hydroxylated), compared to NI vines; however, these effects were more pronounced in the case of early post-veraison irrigation (AVI) than late-season irrigation (MRI). Irrigation also increased the mean Degree of Polymerization (mDP) and prodelphinidin percentage of skin tannins and decreased mDP of seed tannins. In the light of the necessity to control the accelerated ripening under the increasingly hotter and drier climatic conditions, late irrigation (MRI) might provide a solution to avoid excessive sugar levels and allow a slightly higher yield without significant reductions in berry phenolic content. The results suggest that the optimisation of the timing of irrigation could provide an effective adaptation strategy to climate change in Mediterranean viticultural areas.

Impacts of drought and herbicide stress on seed germination and early seedling growth in a legume crop mung bean (Vigna radiata L.)

Abiotic stress such as drought and agrochemicals leads the drastic reductions in legume yields, hence, in order to mitigate the loss of yields due to abiotic stresses, the production of stress tolerance genotypes of the legumes could be a rewarding approach. Therefore, the aim of the present study was to evaluate the drought and herbicide stress effects under ex-vitro conditions on seed germination and early seedling growth in a legume crop mung bean (Vigna radiata L.). To begin with, drought stress was induced by employing various concentrations of mannitol (50mM, 100mM, 250mM, 500mM, 750mM, and 1000mM) and polyethylene glycol (PEG-5%, 10%, 15%, 20%, and 25%) while during herbicide stress experiments, dicamba (3,6-dichloro-2-methoxybenzoic acid) and picloram (4-Amino-3,5,6-trichloro-2-pyridine carboxylic acid) were considered in various concentrations (5mg/L, 25mg/L, 50mg/L, and 100mg/L) of each. Moreover, data were collected as partial and full seed germination after 3- and 7-days of stress treatments respectively. After 7-days of mannitol stress treatments, results reveals that even the high concentration of mannitol (500mM) could be proved as weak osmotic stressor for seed germination (35%±0.14) in comparison to control (91%±0.74) while further increase in mannitol concentration (750mM) was proved to be lethal, toxic and inhibits seed germination completely. Furthermore, in comparison to mannitol, PEG turns out as strong osmotic stressors and (15%) of PEG was proved to very lethal for seed germination. Even during early seedling growth, increased concentrations of both mannitol and PEG were found to be inhibitory. Among two herbicides, the result shows that both herbicides (dicamba and picloram) were proved to be completely toxic and lethal even at very low concentrations (5mg/L) and induced abnormal seed germination and inhibited completely seedling growth. However, the inhibitory response of picloram herbicide stress on seed germination was found to be more pronounced and severe than dicamba herbicide. Hence, the present study reveals that in comparison to mannitol, PEG turns out as a strong osmotic stressor while picloram proves to be a relatively more toxic herbicide than dicamba for seed germination. Additionally, drought stress induced seedlings on transfer to soil exhibit inhibited growth under continuous irrigation with either mannitol or PEG solutions.

PEGADA HÍDRICA DO ARROZ CULTIVADO SOB DIFERENTES MANEJOS DE IRRIGAÇÃO

PEGADA HÍDRICA DO ARROZ CULTIVADO SOB DIFERENTES MANEJOS DE IRRIGAÇÃO EMANUELE BAIFUS MANKE1; ARYANE FARIAS DOS SANTOS2; MARÍLIA ALVES BRITO PINTO²; JOSÉ MARIA BARBART PARFITT3; ADILSON LUÍS BAMBERG3 E LESSANDRO COLL FARIA2 1Doutora em Ciências, Faculdade de Agronomia Eliseu Maciel, Universidade Federal de Pelotas, UFPel. Capão do Leão, RS, Brasil, [email protected] ²Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, UFPel. Pelotas, RS, Brasil, [email protected]; [email protected]; [email protected] 3Embrapa Clima Temperado, Empresa Brasileira de Pesquisa Agropecuária, Embrapa, Pelotas, RS, [email protected]; [email protected] 1 RESUMO O arroz é um dos cereais mais produzidos e consumidos no mundo. O manejo da água na orizicultura é complexo, sendo os estudos acerca da pegada hídrica do arroz menos frequentes em relação a outras culturas. O objetivo deste trabalho foi estimar de forma simplificada a pegada hídrica do arroz irrigado por aspersão e inundação sob diferentes manejos de irrigação, adotando como base a metodologia tradicional de estimativa da pegada hídrica. Os dados utilizados são provenientes de dois experimentos conduzidos na Estação Experimental Terras Baixas, Empresa Brasileira de Pesquisa Agropecuária (Embrapa) Clima Temperado, Capão do Leão, RS, Brasil. No Experimento 1 foram analisados três manejos de irrigação na safra do arroz de 2011/2012 e quatro na safra de 2012/2013. No Experimento 2 foram analisados quatro manejos de irrigação nas safras 2015/2016 e 2016/2017. Os manejos nas tensões de 20 e 10 kPa (aspersão) e por irrigação contínua (inundação) apresentaram menor pegada hídrica simplificada. Comparando-se a irrigação por aspersão e inundação, concluiu-se que na inundação, o manejo de irrigação contínua resultou em uma pegada hídrica simplificada menor. Palavras-chave: Oryza sativa, métodos de irrigação, inundação, aspersão MANKE, E. B.; SANTOS, A. F. dos; PINTO, M. A. B.; PARFITT, J. M. B.; BAMBERG, A. L.; FARIA, L. C. WATER FOOTPRINT OF RICE CULTIVATED UNDER DIFFERENT IRRIGATION MANAGEMENTS 2 ABSTRACT Rice is one of the most produced and consumed cereals in the world. The water management in rice farming is complex, and studies on the rice water footprint are less frequent than other cultures. The objective was to estimate the simplified water footprint of a sprinkler and flood-irrigated rice under different irrigation management, taking as model the traditional methodology of water footprint estimation. The raw data used are from two experiments performed using rice in the “Terras Baixas”, Experimental Station, Brazilian Agricultural Research Corporation (Embrapa) Temperate Climate, located in Capão do Leão, RS, Brazil. In Experiment 1, three irrigation management applied in the rice cropping season of 2011/2012 and four in the cropping season of 2012/2013 were analyzed. In Experiment 2, four irrigation managements in the 2015/2016 and 2016/2017 cropping seasons were evaluated. The irrigation managements in the tensions of 20 and 10 kPa (sprinkler) and continuous irrigation (flood) presented smallest simplified water footprint. Comparing sprinkler and flood irrigation, it can be concluded that the flood method, under continuous irrigation, resulted in a smallest simplified water footprint. Keywords: Oryza sativa, irrigation methods, flooded, sprinkler

Enhancement of water productivity with surge irrigation

Surge irrigation is the intermittent application of water to surface irrigated furrows or borders in a series of relatively short on and off time periods during the irrigation which may be between 20 minutes to two hours. In this technique, water is usually applied intermittently rather than with a continuous stream, as in conventional surface irrigation..Water productivity and water saving of six crops viz. wheat, cotton, maize, capsicum, onion and fennel under surge irrigation were compared with traditional method for the crops grown in different environmental conditions at different location of the world.It is concluded that surge flow irrigation performs better than continuous flow irrigation in terms of water saving and yield resulting in enhancement of water productivity. In case of wheat crop, surge irrigation saved and decreased irrigation water by 27, 33.4 and 37.4 % and increased yield by 15.1, 17.7 and 12.7 % under slope of 0.0, 0.1 and 0.2 % respectively compared with continuous flow irrigation for the same discharge. It had the maximum water use efficiency values of 1.39, 1.56 and 1.59 kg/m3 for surge flow irrigation under slopes of 0.0, 0.1 and 0.2 %, respectively.Surge irrigation system for maize obtained the highest value of WUE (1.63 kg/m3) with 40 m furrow length under 12.24 l/min inflow rate, while the lowest value of WUE obtained by continuous irrigation system, with 20 m furrow length under 44.4 l/min inflow rate (1.05 kg/m3). It can be applied by farmers in areas where irrigation water is limiting factor in crop production and farmers cannot afford costly micro-irrigation system.

Physiological and root morphological responses in different combinations of rootstock-scion of cacao to water deficit

Grafting is a common practice in cacao cultivation, but it has not been reported whether rootstock-scion combinations respond differently in terms of water transport, growth, or nutrient uptake under varying soil water availability conditions. The effects of water deficits on water potential (Ψf), basal diameter (db), root growth, chlorophyll and leaf concentrations of nitrogen (N) were evaluated in 16 rootstock-scion combinations that resulted from four rootstocks and four scion clones. Grafted seedlings were subjected to two water regimes: 21 days without irrigation (WD) and continuous irrigation (I). Under WD conditions, Ψf tended to be lower when using the EETP800 clone with the four rootstocks, indicating that this clone may have a higher rate of transpiration. The greater Ψf (p <0.05) obtained with the EET400 and EET399 rootstocks-scion combinations indicate higher water uptake capacity by the root systems of these rootstocks, which permits the maintenance of adequate transpiration rates and higher Ψf. The higher db, chlorophyll content and leaf N content obtained in the combinations of scions with the EET400 rootstock under WD impart on this rootstock a more favorable degree of adaptability for tolerating water deficits. However, this tolerance is not associated with increased root growth, which indicates that higher efficiency of water uptake is related to metabolic and physiological processes rather than a larger root surface.