Nanometre size wear debris generated from crosslinked and non-crosslinked ultra high molecular weight polyethylene in artificial joints

Wear ◽  
2005 ◽  
Vol 259 (7-12) ◽  
pp. 977-983 ◽  
Author(s):  
Alison L. Galvin ◽  
Joanne L. Tipper ◽  
Eileen Ingham ◽  
John Fisher
Wear ◽  
2009 ◽  
Vol 266 (1-2) ◽  
pp. 349-355 ◽  
Author(s):  
Monika Lapcikova ◽  
Miroslav Slouf ◽  
Jiri Dybal ◽  
Eva Zolotarevova ◽  
Gustav Entlicher ◽  
...  

Author(s):  
J L Hailey ◽  
E Ingham ◽  
M Stone ◽  
B M Wroblewski ◽  
J Fisher

The objective of this study was to investigate the effect of counterface roughness and lubricant on the morphology of ultra-high molecular weight polyethylene (UHMWPE) wear debris generated in laboratory wear tests, and to compare this with debris isolated from explanted tissue. Laboratory tests used UHMWPE pins sliding against stainless steel counterfaces. Both water and serum lubricants were used in conjunction with rough and smooth counterfaces. The lubricants and tissue from revision hip surgery were processed to digest the proteins and permit filtration. This involved denaturing the proteins with potassium hydroxide (KOH), sedimentation of any remaining proteins, and further digestion of these proteins with chromic acid. All fractions were then passed through a 0.2 μm membrane, and the debris examined using scanning electron microscopy. The laboratory studies showed that the major variable influencing debris morphology was counterface roughness. The rougher counter-faces produced larger numbers of smaller particles, with a size range extending below 1 μm. For smooth counterfaces there were fewer of these small particles, and evidence of larger platelets, greater than 10 μm in diameter. Analysis of the debris from explanted tissues showed a wide variation in the particle size distribution, ranging from below 1 μm up to several millimetres in size. Of major clinical significance in relation to osteolysis and loosening is roughening of the femoral components, which may lead to greater numbers of the sub-micron-sized particles.


Author(s):  
Takuya NANBU ◽  
Tatsuki MATSUURA ◽  
Yoshitaka NAKANISHI ◽  
Mutsumi TOUGE ◽  
Hiroshi MIZUTA ◽  
...  

2021 ◽  
Vol 11 (4) ◽  
pp. 1703
Author(s):  
Jack Turicek ◽  
Nicole Ratts ◽  
Matey Kaltchev ◽  
Nazieh Masoud

Ultra-high molecular weight polyethylene (UHMWPE) is one of the most commonly used polymers in joint replacements because of its biologically inert properties and low friction coefficient. However, it has downfalls relating to its wear, adhesion, and lubrication. In this study, UHMWPE samples were treated with a tubular helium cold atmospheric pressure (CAP) plasma source in order to improve three properties of the polymer: (1) its wear resistance, which was characterized by durometer hardness, (2) its lubrication characterized by water contact angle, and (3) its adhesion characterized by both root mean square surface roughness (Rq) and water contact angle. The polymer was treated by two different parts of the plasma plume (the base and the tip) at two different helium flow rates (1 L/min and 2.5 L/min), for different treatment times. Results of the plasma treatment showed a decrease in the contact angle of between 32 and 54 degrees, a significant increase in the roughness by up to 10 times the pristine surface, and no substantial change in the hardness. These improvements to the adhesion and lubrication properties of the polymer examined suggest that the treated surface could be more suitable for use in artificial joints.


Author(s):  
Kimberly D. Mimnaugh ◽  
Alex P. Stoller

The function of the locking mechanism between the ultra high molecular weight polyethylene (UHMWPE) articular surface and the tibial baseplate is to ensure that the two components remain connected and to minimize the relative motion that may occur between them. This relative motion that can occur between the two components has the potential to generate wear debris, which may eventually lead to bone osteolysis [1–2].


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