Poor Prognosis and Challenging Treatment of Optic Nerve Malignant Gliomas: Literature Review and Case Report Series

Purpose: To report on posterior ischemic optic neuropathies, a vascular disorder that happens in the posterior part of the optic nerve and therefore, usually does not present with optic disc edema. Case Report: This is a case report on a posterior ischemic optic neuropathy with an uncharacteristic presentation. It highlights the importance of understanding the different pathophysiology of PION vs anterior ischemic optic neuropathies in order to help differentiate the two clinically and includes a literature review of posterior ischemic optic neuropathy.

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Optic nerve aplasia: A case report and literature review

Journal of Pediatric Neurosciences ◽

10.4103/1817-1745.43645 ◽

2008 ◽

Vol 3 (2) ◽

pp. 150 ◽

Cited By ~ 2

Author(s):

Jerman Alqahtani

Keyword(s):

Case Report ◽

Optic Nerve ◽

Literature Review

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Adding Water to the Mill: Olmesartan-Induced Collagenous Sprue—A Case Report and Brief Literature Review

Canadian Journal of Gastroenterology and Hepatology ◽

10.1155/2016/4837270 ◽

2016 ◽

Vol 2016 ◽

pp. 1-2 ◽

Cited By ~ 5

Author(s):

Claudine Desruisseaux ◽

Michaël Bensoussan ◽

Etienne Désilets ◽

Hanh-Khiem Tran ◽

Robert Arcand ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Clinical Remission ◽

Poor Prognosis ◽

Significant Proportion ◽

Rare Condition ◽

Gluten Free Diet ◽

Gluten Free ◽

Unique Case

Collagenous sprue (CS) is a distinct clinicopathological disorder histologically defined by a thickened subepithelial band (Freeman, 2011). It is a rare condition which has been recently observed in a significant proportion of sprue-like enteropathy associated with olmesartan, a novel entity described by Rubio-Tapia et al. in 2012. CS is historically associated with a poor prognosis (Marthey et al., 2014). However, histological and clinical improvements have been described in most studies with concomitant usage of corticosteroids and/or gluten-free diet (Marthey et al., 2014). We report a unique case of olmesartan-induced collagenous sprue in a 79-year-old man that showed complete histological and clinical remission with the sole withdrawal of the incriminating drug. The literature on this topic is briefly reviewed.

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Mixed adenocarcinoma-neuroendocrine cancer – a case report

European Journal of Clinical and Experimental Medicine ◽

10.15584/ejcem.2020.4.13 ◽

2021 ◽

Vol 18 (4) ◽

pp. 335-337

Author(s):

Joanna Gustalik ◽

◽

David Aebisher ◽

Ewa Kaznowska ◽

Dorota Bartusik-Aebisher ◽

...

Keyword(s):

Ischemic Stroke ◽

Case Report ◽

Literature Review ◽

Poor Prognosis ◽

Neuroendocrine Cells ◽

Double Vision ◽

Rare Cancer ◽

Clinical Behavior ◽

Neuroendocrine Cancer ◽

Intermediate Cells

Introduction. Mixed adenocarcinoma-neuroendocrine cancer (MANEC) is a rare cancer that is characterized by aggressive course and poor prognosis. Aim. A case report and literature review. Description of the case. This article presents the case of a 63-year-old patient who was hospitalized due to the occurrence of neurological symptoms such as nausea, dizziness and headache as well as double vision and numbness of the hands. Suspected ischemic stroke, meningitis with bacterial etiology or brainstem pathology. Conclusion. MANEC composed of large neuroendocrine cells have better survival and clinical behavior than patients with small, intermediate or mixed large and intermediate cells.

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Paraneoplastic leukemoid reaction associated with poor prognosis in oral squamous cell carcinoma: A case report and literature review

Journal of Medical Sciences ◽

10.4103/jmedsci.jmedsci_86_19 ◽

2020 ◽

Vol 40 (1) ◽

pp. 42

Author(s):

Sheng-Yow Ho ◽

Li-Tsun Hsieh ◽

Chien-Liang Lin ◽

Yu-Kang Chang

Keyword(s):

Squamous Cell Carcinoma ◽

Case Report ◽

Oral Squamous Cell Carcinoma ◽

Literature Review ◽

Cell Carcinoma ◽

Squamous Cell ◽

Poor Prognosis ◽

Leukemoid Reaction

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Malignant Mesothelioma of the Epididymis: A Case Report of a Rare Paratesticular Neoplasm and Literature Review

Surgical Case Reports ◽

10.31487/j.scr.2020.12.16 ◽

2020 ◽

pp. 1-3

Author(s):

Jasser Maatougui ◽

Mehdi Raboudi ◽

Tarek Taktak ◽

Issam Msakni ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Malignant Mesothelioma ◽

Poor Prognosis ◽

Histopathological Examination ◽

Multidisciplinary Management ◽

Case Presentation ◽

Scrotal Ultrasound ◽

Disease Free

Background: Malignant mesothelioma of the epididymis is an extremely rare neoplasm with a poor prognosis and high potential of recurrence. Case Presentation: We report a case of a 28-year-old male with a left painless epididymal nodule. Scrotal ultrasound revealed a nodular mass with mixed echogenicity and Doppler showed increased vascularity. Radical orchidectomy was performed. Histopathological examination concluded to a malignant mesothelioma involving the epididymis. Metastatic workup was negative. The patient has undergone a regular follow-up and has been disease-free within 6 months. Conclusion: Malignant mesothelium of the epididymis is a diagnosis challenge. Surgery remains the main treatment. A multidisciplinary management should be offered in those cases.

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