Preparation and Evaluation of Quinapyramine Sulphate-Docusate Sodium Ionic Complex Loaded Lipidic Nanoparticles and Its Scale Up Using Geometric Similarity Principle

2021 ◽  
Vol 110 (5) ◽  
pp. 2241-2249
Author(s):  
Kedar S. Prayag ◽  
Atish T. Paul ◽  
Samar Kumar Ghorui ◽  
Anil B. Jindal
Metals ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 979 ◽  
Author(s):  
Lv ◽  
Zhang ◽  
Hao

Micro- and nano-sized cerium oxide particles can be prepared through pyrolyzing cerium chloride solution directly in the venturi jet pyrolysis reactor. Micro- and nano-sized cerium oxide particles have better performance and higher application value. To increase the production of micro-and nano-sized cerium oxide, it is necessary to scale up the venturi jet pyrolysis reactor. According to the geometric similarity principle, the scale-up of the venturi jet pyrolysis reactors utilize dimensional analysis methods, with FLUENT13.0 and user-defined functions, following the mathematical simulation of the resulting enlarged reactors. After the dimensional analysis, the empirical formula obtained between the reactants and all the parameters is Q = 2.240727 × 10−4P0.004568ρ0.26223d−0.24801V1.25714n0.076479μ−0.26628, and the geometrical scale-up of the reactors needs to follow V = 0.0209d0.196. The results in this study can provide data support for the future optimization and amplification of reactors.


2013 ◽  
Vol 586 ◽  
pp. 47-50
Author(s):  
Jaroslav Menčík

The paper summarizes principles of similarity and shows where they loose their validity in material tests by indentation and what should be considered in their preparation and evaluation.


Author(s):  
L.E. Murr ◽  
J.S. Dunning ◽  
S. Shankar

Aluminum additions to conventional 18Cr-8Ni austenitic stainless steel compositions impart excellent resistance to high sulfur environments. However, problems are typically encountered with aluminum additions above about 1% due to embrittlement caused by aluminum in solid solution and the precipitation of NiAl. Consequently, little use has been made of aluminum alloy additions to stainless steels for use in sulfur or H2S environments in the chemical industry, energy conversion or generation, and mineral processing, for example.A research program at the Albany Research Center has concentrated on the development of a wrought alloy composition with as low a chromium content as possible, with the idea of developing a low-chromium substitute for 310 stainless steel (25Cr-20Ni) which is often used in high-sulfur environments. On the basis of workability and microstructural studies involving optical metallography on 100g button ingots soaked at 700°C and air-cooled, a low-alloy composition Fe-12Cr-5Ni-4Al (in wt %) was selected for scale up and property evaluation.


Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
RS Barboza ◽  
BR Rocha ◽  
AC Siani ◽  
LMM Valente ◽  
JL Mazzei
Keyword(s):  

1970 ◽  
Vol 23 (02) ◽  
pp. 202-210 ◽  
Author(s):  
R Bishop ◽  
H Ekert ◽  
G Gilchrist ◽  
E Shanbrom ◽  
L Fekete

SummaryA new fibrin plate technic for evaluating components of the fibrinolytic system has been developed. It provides quick, accurate, and easily interpreted results for the fibrinolytic profile. The standardized human plasminogen-free fibrin plates can be produced in bulk and stored for prolonged periods of time. A test specimen placed in a well punched in the buffered agarose gel diffuses into the agar and lyses the fibrin clot, forming a clear reaction zone. The zone diameter is directly proportional to the log of the percent concentration of available fibrinolytic enzyme in the specimen. The plates may be used to quantitate total plasminogen, and estimate available plasmin and active plasmin. A good correlation between results obtained using these fibrin plates and caseinolytic methods was found. Performance and interpretation of tests of fibrinolysis done on these new fibrin plates indicate that it may be the most sensitive technic available for clinical laboratory work.


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