scholarly journals A novel diagnostic nomogram based on serological and ultrasound findings for preoperative prediction of malignancy in patients with ovarian masses

Author(s):  
Yunyun Guo ◽  
Tengjia Jiang ◽  
Linglong Ouyang ◽  
Xiaohui Li ◽  
Weipeng He ◽  
...  
BMJ Open ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. e046334
Author(s):  
Mohammed Bukar ◽  
Asta Umar Mana ◽  
Nasiru Ikunaiye

ObjectiveTo determine if the presence or absence of sonographic sliding sign preoperatively is a good predictor of the presence and type of intra-abdominal adhesions; and to determine the time taken to demonstrate this sign.DesignA prospective, observational, triple-blind study using tests of diagnostic accuracy.SettingSingle-centre tertiary health institution in north-east Nigeria.Participants67 women in the third trimester scheduled for repeat elective caesarean sections (CS) had transabdominal sonography to determine the absence or presence and degree of sliding sign. The time taken to make these decisions were noted. Surgeons blinded to the ultrasound findings graded adhesions intraoperatively and comparison between sonographic and intraoperative findings made. Women who were scheduled for emergency CS were excluded.Main outcome measuresAccuracy of preoperative ultrasound to determine no/mild, moderate and severe adhesions. Secondary outcomes were interobserver correlations and time taken to determine sliding.ResultsWhen classified as adhesion and no adhesion, the sliding sign demonstrated a sensitivity of 100.00% (CI95 85.18% to 100.00%), specificity of 100.00% (CI95 92.13% to 100.00%). In predicting presence of moderate intra-abdominal adhesions, a sensitivity of 65.0% (CI95 40.78% to 84.61%) and specificity of 82.98% (CI95 69.19% to 92.35%) was found. For predicting severe intra-abdominal adhesions, it had a sensitivity of 25.00% (CI95 0.63% to 80.59%) and specificity of 98.41 (CI95 91.47 to 99.96). Disease prevalence for mild, moderate and severe adhesions was 33.82% (CI95 22.79% to 46.32%), 29.85% (CI95 19.28% to 42.27%) and 5.97% (CI95 1.65% to 14.59%), respectively. Interobserver Cohen’s kappa coefficient and PPA were 0.58 (CI95 0.39 to 0.76) and 58.82 (CI95 52.82 to 64.82), respectively. The mean duration to determine sliding sign was 7.56±2.86 s.ConclusionThis study supports the role of transabdominal sliding sign in preoperative prediction of intra-abdominal adhesions in women with previous CS without significant increase in sonography duration. This information can encourage planning for CS by ensuring that surgeons of appropriate seniority are deployed to undertake anticipated complex operations.


1968 ◽  
Vol 54 (4) ◽  
pp. 267-289
Author(s):  
Bruno Damascelli ◽  
Angelo Lattuada ◽  
Renato Musumeci ◽  
Aldo Severini

Ultrasound scanning of the soft tissues has been used increasingly at clinical level for some years now, especially for investigating abdominal organs and abdominopelvic space-occupying lesions, whose intrinsic structure they delineate. This paper deals with the practical applications of ultrasound and compares the information it supplies with that supplied by the simpler and least traumatic radiologic investigations in 60 cases of abdominopelvic swellings. In all the patients ultrasound demonstrated space-occupying lesions and in 52 cases specified whether the mass was cystic or solid, whether a cyst was uni- or multilocular and whether a solid mass was homogeneous or not. In this series only one multilocular ovarian cystocarcinoma was mistaken for a solid mass. Compared with routine X-ray investigations, the ultrasound findings proved to be superfluous in 33 cases and contributory in 27. The latter were mainly utero-ovarian masses, hepatomegalies, swellings of nonfunctioning kidneys or gallbladders and serous cysts.


BMC Cancer ◽  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Denise da Rocha Pitta ◽  
Luis Otávio Sarian ◽  
Amilcar Barreta ◽  
Elisabete Aparecida Campos ◽  
Liliana Lucci de Angelo Andrade ◽  
...  

Diagnostics ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 106
Author(s):  
Katherine Jane C. Chua ◽  
Ricky D. Patel ◽  
Radhika Trivedi ◽  
Patricia Greenberg ◽  
Kyle Beiter ◽  
...  

Ovarian cancer is one of the most lethal gynecological cancers in women due to late diagnosis. Despite technological advancements, experienced physicians have high sensitivities and specificities in subjective assessments when combining ultrasound findings and clinical history in analyzing adnexal masses. This study aims to demonstrate general obstetricians and gynecologists’ (OB/GYN) appropriateness in gynecologic oncologist referrals for malignant ovarian masses based on history and physical (H&P), imaging, and available tumor markers. Three board certified OB/GYNs were given 148 cases and determined whether or not they would refer them to a gynecologic oncologist. Results showed that OB/GYNs were 81–85% accurate in diagnosing patients with a benign or malignant disease. Among the malignant cases, reviewers had a high sensitivity ranging from 74–81% in appropriately referring a malignancy. In our study, OB/GYNs referred between 23–32% of ovarian masses to a gynecologic oncologist with only 9.5% of cases found to be malignant. Despite the high referral rates, generalists showed a high degree of sensitivity in accurately referring malignant diseases based solely on clinical experience and imaging studies, which could improve survival rates with early intervention by gynecologic oncologists.


2015 ◽  
Vol 21 ◽  
pp. 200
Author(s):  
Adriana Herrera ◽  
Claudia Zapata ◽  
Parul Jayakar ◽  
Aparna Rajadhyaksha ◽  
Ricardo Restrepo ◽  
...  

Author(s):  
Yale Tung Chen ◽  
Milagros Martí de Gracia ◽  
Maria Luz Parra Gordo ◽  
Silvia Ossaba Velez ◽  
Sergio Agudo-Fernández

Choonpa Igaku ◽  
2013 ◽  
Vol 40 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Yukio MITSUZUKA ◽  
Shinsaku KANAZAWA ◽  
Hideaki OGATA ◽  
Kenichi MARUYAMA ◽  
Tsuneyoshi YAKUWA ◽  
...  

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