Prokineticin-2 and ghrelin robustly influence the sexual and ingestive behaviors of female Syrian hamsters

2018 ◽  
Vol 106 ◽  
pp. 135-143 ◽  
Author(s):  
S. Burroughs ◽  
W.F. Schwindinger ◽  
J.J. Venditti ◽  
T. Trautwein ◽  
A. Dalsania ◽  
...  
Keyword(s):  
Syrian Hamsters ◽  
Prokineticin 2 ◽  
Ingestive Behaviors

Postnatal growth rate and gonadal development in circadian tau mutant hamsters reared in constant dim red light

Reproduction ◽  
2000 ◽  
pp. 327-330 ◽  
Author(s):  
RJ Lucas ◽  
JA Stirland ◽  
YN Mohammad ◽  
AS Loudon
Keyword(s):  
Time Course ◽  
Red Light ◽  
Somatic Growth ◽  
Postnatal Growth ◽  
Gonadal Development ◽  
Testicular Development ◽  
Wild Type ◽  
Similar Time ◽  
Syrian Hamsters ◽  
Body Weights

The role of the circadian clock in the reproductive development of Syrian hamsters (Mesocricetus auratus was examined in wild type and circadian tau mutant hamsters reared from birth to 26 weeks of age under constant dim red light. Testis diameter and body weights were determined at weekly intervals in male hamsters from 4 weeks of age. In both genotypes, testicular development, subsequent regression and recrudescence exhibited a similar time course. The age at which animals displayed reproductive photosensitivity, as exhibited by testicular regression, was unrelated to circadian genotype (mean +/- SEM: 54 +/- 3 days for wild type and 59 +/- 5 days for tau mutants). In contrast, our studies revealed a significant impact of the mutation on somatic growth, such that tau mutants weighed 18% less than wild types at the end of the experiment. Our study reveals that the juvenile onset of reproductive photoperiodism in Syrian hamsters is not timed by the circadian system.

Flaxseed and Vitamin E Exert Synergic Antioxidant Action on Diabetic Nephropathy in Experimental Diabetes

2017 ◽  
Vol 68 (7) ◽  
pp. 1449-1452 ◽  
Author(s):  
Raluca Ecaterina Haliga ◽  
Doina Butcovan ◽  
Teodor Oboroceanu ◽  
Alin Constantin Pinzariu ◽  
Victor Vlad Costan ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Vitamin E ◽  
Intraperitoneal Injection ◽  
Experimental Diabetes ◽  
Histological Evaluation ◽  
Standard Diet ◽  
Antioxidant Action ◽  
Syrian Hamsters

This study investigated the effects of flaxseed and vitamin E on diabetic nephropathy lesions in an experimental-induced model of diabetes in hamsters. Diabetes was induced by intraperitoneal injection of streptozotocin (STZ) in male Golden Syrian hamsters, and diabetic animals were fed either standard diet, or standard diet supplemented with flaxseed (150 g/kg diet), vitamin E (400 mg a-tocopherol/kg diet) or combination of flaxseed and vitamin E in the same dosages, for 20 weeks. Kidney histological evaluation of the diabetic hamsters revealed histological lesions characteristic for diabetic nephropathy, while supplementation of the diet with flaxseed and/or vitamin E improved histological aspects of diabetic nephropathy.

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

2020 ◽  
Author(s):  
Andrew Chak-Yiu Lee ◽  
Anna Jinxia Zhang ◽  
Jasper Fuk-Woo Chan ◽  
Can Li ◽  
Zhimeng Fan ◽  
...  
Keyword(s):  
Respiratory Infection ◽  
Virus Shedding ◽  
Syrian Hamsters

Rust, a New Mutation in Syrian Hamsters

1964 ◽  
Vol 98 (899) ◽  
pp. 121-122 ◽  
Author(s):  
Rae Whitney ◽  
Gail Burns ◽  
C. W. Nixon
Keyword(s):  
New Mutation ◽  
Syrian Hamsters

scholarly journals Protective efficacy of a SARS-CoV-2 DNA vaccine in wild-type and immunosuppressed Syrian hamsters

npj Vaccines ◽  
2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Rebecca L. Brocato ◽  
Steven A. Kwilas ◽  
Robert K. Kim ◽  
Xiankun Zeng ◽  
Lucia M. Principe ◽  
...  
Keyword(s):  
Dna Vaccine ◽  
Neutralizing Antibodies ◽  
Protective Efficacy ◽  
Phase 1 ◽  
Severe Disease ◽  
Disease Model ◽  
Wild Type ◽  
Jet Injection ◽  
Syrian Hamsters ◽  
Dna Targeting

AbstractA worldwide effort to counter the COVID-19 pandemic has resulted in hundreds of candidate vaccines moving through various stages of research and development, including several vaccines in phase 1, 2 and 3 clinical trials. A relatively small number of these vaccines have been evaluated in SARS-CoV-2 disease models, and fewer in a severe disease model. Here, a SARS-CoV-2 DNA targeting the spike protein and delivered by jet injection, nCoV-S(JET), elicited neutralizing antibodies in hamsters and was protective in both wild-type and transiently immunosuppressed hamster models. This study highlights the DNA vaccine, nCoV-S(JET), we developed has a great potential to move to next stage of preclinical studies, and it also demonstrates that the transiently-immunosuppressed Syrian hamsters, which recapitulate severe and prolonged COVID-19 disease, can be used for preclinical evaluation of the protective efficacy of spike-based COVID-19 vaccines.

scholarly journals The G614 pandemic SARS-CoV-2 variant is not more pathogenic than the original D614 form in adult Syrian hamsters

Virology ◽  
2021 ◽  
Vol 556 ◽  
pp. 96-100
Author(s):  
Charles B. Stauft ◽  
Christopher Z. Lien ◽  
Prabhuanand Selvaraj ◽  
Shufeng Liu ◽  
Tony T. Wang
Keyword(s):  
Syrian Hamsters
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