Subchronic toxicity evaluation of isoeugenyl methyl ether in F344/DuCrj rats by 13-week oral administration

2019 ◽  
Vol 102 ◽  
pp. 34-39 ◽  
Author(s):  
Jun-ichi Akagi ◽  
Young-Man Cho ◽  
Yasuko Mizuta ◽  
Chiye Tatebe ◽  
Kyoko Sato ◽  
...  
Keyword(s):  
Oral Administration ◽  
Methyl Ether ◽  
Toxicity Evaluation ◽  
Subchronic Toxicity

Systematic acute and subchronic toxicity evaluation of polysaccharide–protein complex-functionalized selenium nanoparticles with anticancer potency

2019 ◽  
Vol 7 (12) ◽  
pp. 5112-5123 ◽  
Author(s):  
Zehang Zhang ◽  
Yanxin Du ◽  
Ting Liu ◽  
Ka-Hing Wong ◽  
Tianfeng Chen
Keyword(s):  
Oral Administration ◽  
Anticancer Activity ◽  
Surface Properties ◽  
Protein Complex ◽  
Large Scale ◽  
Selenium Nanoparticles ◽  
Toxicity Evaluation ◽  
Subchronic Toxicity ◽  
Reduced Toxicity

Herein we provide a strategy for facile and large-scale manufacturing of SeNPs with reduced toxicity and enhanced anticancer activity via oral administration through the regulation of the surface properties.

scholarly journals Mouse Model for Assessing the Subchronic Toxicity of Organophosphate Pesticides

Acta Naturae ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 125-128
Author(s):  
V. A. Palikov ◽  
S. S. Terekhov ◽  
Yu. A. Palikova ◽  
O. N. Khokhlova ◽  
V. A. Kazakov ◽  
...  
Keyword(s):  
Mouse Model ◽  
Oral Administration ◽  
High Activity ◽  
Rapid Recovery ◽  
In Vivo Model ◽  
Organophosphate Poisoning ◽  
Organophosphate Pesticides ◽  
Protective Agent ◽  
Subchronic Toxicity

The development of antidotes to organophosphate poisons is an important aspect of modern pharmacology. Recombinant acetylcholinesterase and butyrylcholinesterase are effective DNA-encoded acceptors of organophosphate poisons and, in particular, pesticides. Here, we present the results of a study on the effectiveness of recombinant butyrylcholinesterase (BChE) in modeling organophosphate poisoning caused by oral administration of paraoxon at a dose of 2 mg / kg. The study showed a high activity of BChE as a protective agent for subchronic anticholinesterase poisoning in an in vivo model. The administration of BChE in a dose of 20 mg / kg allows one to avoid mortality, and also contributed to rapid recovery after model poisoning.

Subchronic Toxicity Evaluation of Tridecyl Acetate in Rats

1990 ◽  
Vol 14 (1) ◽  
pp. 104-112
Author(s):  
WAYNE C. DAUGHTREY ◽  
JACQUELINE H. SMITH ◽  
JOHN P. HINZ ◽  
ROBERT W. BILES
Keyword(s):  
Toxicity Evaluation ◽  
Subchronic Toxicity

Subchronic toxicity study of gallic acid by oral administration in F344 rats

2001 ◽  
Vol 39 (11) ◽  
pp. 1063-1070 ◽  
Author(s):  
N Niho ◽  
M Shibutani ◽  
T Tamura ◽  
K Toyoda ◽  
C Uneyama ◽  
...  
Keyword(s):  
Oral Administration ◽  
Gallic Acid ◽  
Toxicity Study ◽  
Subchronic Toxicity ◽  
F344 Rats

Subchronic toxicity evaluation of potato protein isolates

2012 ◽  
Vol 50 (2) ◽  
pp. 373-384 ◽  
Author(s):  
B. Lynch ◽  
R.R. Simon ◽  
F.M. van Otterdijk ◽  
H.H. Emmen ◽  
M.L.F. Giuseppin ◽  
...  
Keyword(s):  
Toxicity Evaluation ◽  
Subchronic Toxicity ◽  
Potato Protein ◽  
Protein Isolates

Subchronic toxicity evaluation of γ-aminobutyric acid (GABA) in rats

2014 ◽  
Vol 68 ◽  
pp. 128-134 ◽  
Author(s):  
Kazuhito Takeshima ◽  
Atsushi Yamatsu ◽  
Yusuke Yamashita ◽  
Kazuya Watabe ◽  
Noriko Horie ◽  
...  
Keyword(s):  
Aminobutyric Acid ◽  
Toxicity Evaluation ◽  
Subchronic Toxicity
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